Clinical Research

1119 results

Identifying children with neurological impairment and disability in resource-poor countries.Mung'ala-Odera V, Newton CR
Child Care Health Dev, (2007). 33:249-56

Phase III trials required to resolve clinical equipoise over optimal fluid management in children with severe malaria.Maitland K, Akech S, Gwer S, Idro R, Fegan G, Eziefula AC, Levin M, Newton CR
PLoS Clin Trials, (2007). 2:e2

Population pharmacokinetics of a single daily intramuscular dose of gentamicin in children with severe malnutrition.Seaton C, Ignas J, Muchohi S, Kokwaro G, Maitland K, Thomson AH
J Antimicrob Chemother, (2007). 59:681-9

A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis.Khor CC, Chapman SJ, Vannberg FO, Dunne A, Murphy C, Ling EY, Frodsham AJ, Walley AJ, Kyrieleis O, Khan A, Aucan C, Segal S, Moore CE, Knox K, Campbell SJ, Lienhardt C, Scott A, Aaby P, Sow OY, Grignani RT, Sillah J, Sirugo G, Peshu N, Williams TN, Maitland K, Davies RJ, Kwiatkowski DP, Day NP, Yala D, Crook DW, Marsh K, Berkley JA, O'Neill LA, Hill AV
Nat Genet, (2007). 39:523-8

Initiation of antiretroviral therapy leads to a rapid decline in cervical and vaginal HIV-1 shedding.Graham SM, Holte SE, Peshu NM, Richardson BA, Panteleeff DD, Jaoko WG, Ndinya-Achola JO, Mandaliya KN, Overbaugh JM, McClelland RS
AIDS, (2007). 21:501-7

Investigating the utility of the HIV-1 BED capture enzyme immunoassay using cross-sectional and longitudinal seroconverter specimens from Africa.Karita E, Price M, Hunter E, Chomba E, Allen S, Fei L, Kamali A, Sanders EJ, Anzala O, Katende M, Ketter N
AIDS, (2007). 21:403-8

Elevated plasma urokinase receptor predicts low birth weight in maternal malaria.Ostrowski SR, Shulman CE, Peshu N, Staalsoe T, Hoyer-Hansen G, Pedersen BK, Marsh K, Ullum H
Parasite Immunol, (2007). 29:37-46

A phase 2b randomised trial of the candidate malaria vaccines FP9 ME-TRAP and MVA ME-TRAP among children in Kenya.Bejon P, Mwacharo J, Kai O, Mwangi T, Milligan P, Todryk S, Keating S, Lang T, Lowe B, Gikonyo C, Molyneux C, Fegan G, Gilbert SC, Peshu N, Marsh K, Hill AV
PLoS Clin Trials, (2006). 1:e29

Medical informatics in medical research - the Severe Malaria in African Children (SMAC) Network's experience.Olola CH, Missinou MA, Issifou S, Anane-Sarpong E, Abubakar I, Gandi JN, Chagomerana M, Pinder M, Agbenyega T, Kremsner PG, Newton CR, Wypij D, Taylor TE
Methods Inf Med, (2006). 45:483-91

Volume expansion with albumin compared to gelofusine in children with severe malaria: results of a controlled trial.Akech S, Gwer S, Idro R, Fegan G, Eziefula AC, Newton CR, Levin M, Maitland K
PLoS Clin Trials, (2006). 1:e21

Early gamma interferon and interleukin-2 responses to vaccination predict the late resting memory in malaria-naive and malaria-exposed individuals.Bejon P, Keating S, Mwacharo J, Kai OK, Dunachie S, Walther M, Berthoud T, Lang T, Epstein J, Carucci D, Moris P, Cohen J, Gilbert SC, Peshu N, Marsh K, Hill AV
Infect Immun, (2006). 74:6331-8

The reliability of diagnostic techniques in the diagnosis and management of malaria in the absence of a gold standard.Ochola LB, Vounatsou P, Smith T, Mabaso ML, Newton CR
Lancet Infect Dis, (2006). 6:582-8

Life-threatening hyponatraemia and neurotoxicity during chemotherapy for Burkitt's lymphoma.Osier FH, Berkley JA, Newton CR
Trop Doct, (2006). 36:177-8

Implementation of a structured paediatric admission record for district hospitals in Kenya--results of a pilot study.Mwakyusa S, Wamae A, Wasunna A, Were F, Esamai F, Ogutu B, Muriithi A, Peshu N, English M
BMC Int Health Hum Rights, (2006). 6:9

Alternating vector immunizations encoding pre-erythrocytic malaria antigens enhance memory responses in a malaria endemic area.Bejon P, Kai OK, Mwacharo J, Keating S, Lang T, Gilbert SC, Peshu N, Marsh K, Hill AV
Eur J Immunol, (2006). 36:2264-72

Immunization coverage and risk factors for failure to immunize within the Expanded Programme on Immunization in Kenya after introduction of new Haemophilus influenzae type b and hepatitis b virus antigens.Ndiritu M, Cowgill KD, Ismail A, Chiphatsi S, Kamau T, Fegan G, Feikin DR, Newton CR, Scott JA
BMC Public Health, (2006). 6:132

Immunogenicity of the candidate malaria vaccines FP9 and modified vaccinia virus Ankara encoding the pre-erythrocytic antigen ME-TRAP in 1-6 year old children in a malaria endemic area.Bejon P, Mwacharo J, Kai OK, Todryk S, Keating S, Lang T, Gilbert SC, Peshu N, Marsh K, Hill AV
Vaccine, (2006). 24:4709-15

Safety profile of the viral vectors of attenuated fowlpox strain FP9 and modified vaccinia virus Ankara recombinant for either of 2 preerythrocytic malaria antigens, ME-TRAP or the circumsporozoite protein, in children and adults in Kenya.Bejon P, Peshu N, Gilbert SC, Lowe BS, Molyneux CS, Forsdyke J, Lang T, Hill AV, Marsh K
Clin Infect Dis, (2006). 42:1102-10

Standardized data collection for multi-center clinical studies of severe malaria in African children: establishing the SMAC network.Taylor T, Olola C, Valim C, Agbenyega T, Kremsner P, Krishna S, Kwiatkowski D, Newton C, Missinou M, Pinder M, Wypij D
Trans R Soc Trop Med Hyg, (2006). 100:615-22

Research priorities in the management of severe Plasmodium falciparum malaria in children.Idro R, Aketch S, Gwer S, Newton CR, Maitland K
Ann Trop Med Parasitol, (2006). 100:95-108