Bio

Ambrose is a paediatrician and clinical epidemiologist with a research career spanning more than ten years in epidemiology, implementation science, pragmatic clinical trials, and evidence synthesis with a focus on childhood respiratory infections. Some of his work has ignited debate around the appropriateness of WHO and Kenyan guidelines for the management of pneumonia in children. More recently, he has overseen a large programme of clinical and seroepidemiological surveillance of SARS-CoV-2, contributing towards the few published reports on the unique epidemiology of COVID-19 in Africa.

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Current Work

Ambrose currently co-leads the Clinical Information Network. This collaboration of researchers, policymakers, and practising health professionals at 22 Kenyan hospitals has supported the generation and use of routine data to improve care, understand patient outcomes, and evaluate interventions since 2013. Over the last five years, he has championed the regional growth of this Learning Network to Tanzania, where it is currently running under the leadership of the Paediatric Association of Tanzania. Nationally, Ambrose serves on various Ministry of Health technical panels where he has engaged in developing policy and strategy for newborn, child, and adolescent health. He is also the immediate former co-chair, and a member of the Child Health Accountability Tracking (CHAT) Technical Advisory Group convened by WHO and UNICEF. Collaborations;

  • Other Roles;
  • Adjunct Professor (Department of Pediatrics, Stanford University, USA)
  • Adjunct Faculty (Institute of Healthcare Management, Strathmore University, Kenya
  •  Member, Child Health Accountability Tracking (CHAT) Technical Advisory Group (WHO/UNICEF)
  • Member, Life Course Quality of Care Metrics Working Group (WHO)
  • Member, Child Health Panel of Experts (Ministry of Health, Kenya)
  • National Board member and member of the Scientific Committee (Kenya Paediatric Association)
  • Member, Research Committee Advisory Board (Kenya Medical Association)
  • Member, Keprecon
  • Committee member, Population and Public Health Early Career Advisory Group (Wellcome Trust)

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Recent publications

Pilot implementation of short message service for randomisation in a multisite pragmatic factorial clinical trial in Kenya.
Chepkirui, M., Kimego, D., Nzioki, C., Jowi, E., Opondo, C., Agweyu, A.
Pilot Feasibility Stud, (2025). 11:29

Evaluating the level of knowledge of HIV prevention methods and associated socio-demographic factors among adolescents before and after participating in health education in Nimule town of South Sudan.
Bojo, S., Kokwaro, G., Agweyu, A.
BMC Public Health, (2025). 25:746

Evaluation of population immunity against SARS-CoV-2 variants, EG.5.1, FY.4, BA.2.86, JN.1, JN.1.4, and KP.3.1.1 using samples from two health demographic surveillance systems in Kenya.
Lugano, D., Kutima, B., Kimani, M., Sigilai, A., Gitonga, J., Karani, A., Akech, D., Karia, B., Ziraba, A. K., Maina, A., Lambisia, A., Omuoyo, D., Mugo, D., Lucinde, R., Owuor, S., Konyino, G., Newman, J., Bailey, D., Nduati, E., Githinji, G., Agoti, C. N., Bejon, P., Scott, J. A. G., Agweyu, A., Kagucia, W., Warimwe, G. M., Sande, C., Ochola-Oyier, L. I., Nyagwange, J.
BMC Infect Dis, (2024). 24:1474

Profile: The Kenya Multi-Site Serosurveillance (KEMIS) collaboration .
Kagucia, E. W., Voller, S., Ziraba, A. K., Bigogo, G., Munywoki, P. K., Makobu, K., Nokes, D. J., Nyagwange, J., Orlendo, C., Akech, D., Sigilai, A., Onyango, C., Juma, B., Herman-Roloff, A., Munyua, P., Apondi, C., Lidechi, S., Audi, A., Ouma, A., Aol, G., Misore, T., Nasimiyu, C., Onyango, D., Lo, T., Kasera, K., Jalang'o, R., Kingwara, L., Adetifa, I., Etyang, A. O., Warimwe, G., Agweyu, A., Scott, J. A. G.
Gates Open Res, (2024). 8:

Recommendations for Using Health Service Coverage Cascades to Measure Effective Coverage for Maternal, Newborn, Child, and Adolescent Health Services or Interventions.
Strong, K., Konstantinou, G., Agweyu, A., Diaz, T., Jackson, D., Kim, M., Kubota, S., Leslie, H., Lazzerini, M., Marchant, T., Munos, M., Muzigaba, M., Quach, A., Sheffel, A., Yaqub, N. Jr.
Glob Health Sci Pract, (2024). :