edd/Wellcome Open Res

Coxsackievirus A24 variant whole genome sequencing from clinical samples using a three overlapping amplicons strategy.Morobe JM Odoyo S Lambisia AW Moraa E Houldcroft CJ Holmes EC Githinji G Agoti CN
Wellcome Open Res, (2025). 10:316

GRAPEVNE - Graphical Analytical Pipeline Development Environment for Infectious Diseases.Brittain JS Tsui J Inward R Gutierrez B Mwanyika G Tegally H Huynh T Githinji G Tessema SK McCrone JT Bhatt S Dasgupta A Ratcliffe S Kraemer MUG
Wellcome Open Res, (2025). 10:279

A pragmatic randomized controlled trial of standard care versus corticosteroids plus standard care for treatment of pneumonia in adults admitted to Kenyan hospitals (SONIA).Lucinde R Abdi A Orindi B Mwakio S Gathuri H Onyango E Chira S Ogero M Isaaka L Shangala J Oginga IN Wachira A Manuthu E Kariuki H Nyikuli J Wekesa C Otedo A Bosire H Okoth SB Ongalo W Mukabi D Lusamba W Muthui B Kirui N Adembesa I Mithi C Sood M Ahmed N Gituma B Ongaki VB Giabe M Omondi C Ombajo LA Kagucia W English M Hamaluba M Ochola-Oyier LI Kamuya D Bejon P Agweyu A Akech S Etyang AO
Wellcome Open Res, (2025). 7:269

Identification of coxsackievirus A24 variant during an acute hemorrhagic conjunctivitis outbreak in coastal Kenya, 2024.Lambisia AW Mwita Morobe J Moraa E Mwarumba S Korir FKN Seif Athman R Kiptui R Mbee M Mugo N Amoth P Muange P JHouldcroft C Barasa E Mwangangi J Githinji G CHolmes E Ochola-Oyier LI Agoti CN
Wellcome Open Res, (2025). 10:28

Comparative performance of the InBios SCoV-2 Detect (TM) IgG ELISA and the in-house KWTRP ELISA in detecting SARS-CoV-2 spike IgG antibodies in Kenyan populations.Kutima B Kagucia EW Mwai K Kimani M Sigilai A Mugo D Karanja H Gitonga JN Karani A Akech D Toroitich M Karia B Tuju J Ziraba AK Bigogo G Ochieng C Onyango C Lidechi S Munywoki PK Uyoga S Adetifa IMO Oyier LIO Bejon P Scott JAG Agweyu A Warimwe GM Nyagwange J Kenya Sars-CoV-Serology Consortium
Wellcome Open Res, (2024). 9:349

SEVUparin as a potential Adjunctive Treatment in children with severe malaria: A phase I trial safety and dose finding trial (SEVUSMAART).Maitland K Hamaluba M Obonyo N Oguda E Mogoka C Williams TN Chaponda M Miti S Kamavu LK Jonathan Gwasupika J Connon R Gibb DM Dondorp A Day N White N Walker AS George EC Severe Malaria in African Children AResearch Trials consortium
Wellcome Open Res, (2024). 8:484

A Phase I trial of Non-invasive Ventilation and seizure prophylaxis with levetiracetam In Children with Cerebral Malaria Trial (NOVICE-M Trial).Maitland K Obonyo N Hamaluba M Ogoda E Mogaka C Williams TN Newton C Kariuki SM Gibb DM Walker AS Connon R George EC
Wellcome Open Res, (2024). 9:281

Gastroenteritis Rehydration Of children with Severe Acute Malnutrition (GASTROSAM): A Phase II Randomised Controlled trial: Trial Protocol.Olupot-Olupot P Aloroker F Mpoya A Mnjalla H Paasi G Nakuya M Houston K Obonyo N Hamaluba M Evans JA Dewez M Atti S Guindo O Ouattara SM Chara A Sainna HA Amos OO Ogundipe O Sunyoto T Coldiron M Langendorf C Scherrer MF Petrucci R Connon R George EC Gibb DM Maitland K
Wellcome Open Res, (2024). 6:160

Safety and immunogenicity of ChAdOx1 nCoV-19 (AZD1222) vaccine in adults in Kenya: a phase 1/2 single-blind, randomised controlled trial.Hamaluba M Sang S Orindi B Njau I Karanja H Kamau N Gitonga JN Mugo D Wright D Nyagwange J Kutima B Omuoyo D Mwatasa M Ngetsa C Agoti C Cheruiyot S Nyaguara A Munene M Mturi N Oloo E Ochola-Oyier L Mumba N Mauncho C Namayi R Davies A Tsofa B Nduati EW Aliyan N Kasera K Etyang A Boyd A Hill A Gilbert S Douglas A Pollard A Bejon P Lambe T Warimwe G COVVaccine Trial Group
Wellcome Open Res, (2023). 8:182

Pharmacokinetics and pharmacodynamics of azithromycin in severe malaria bacterial co-infection in African children (TABS-PKPD): a protocol for a Phase II randomised controlled trial.Olupot-Olupot P Okiror W Mnjalla H Muhindo R Uyoga S Mpoya A Williams TN terHeine R Burger DM Urban B Connon R George EC Gibb DM Walker AS Maitland K
Wellcome Open Res, (2023). 6:161

Assessment of gestational age at antenatal care visits among Kenyan women to inform delivery of a maternal respiratory syncytial virus (RSV) vaccine in low- and middle-income countries.Nyiro JU Nyawanda BO Bukusi E Mureithi MW Murunga N Nokes DJ Bigogo G Otieno NA Opere VA Ouma A Pecenka C Munywoki PK
Wellcome Open Res, (2023). 8:154

Revealing the extent of the first wave of the COVID-19 pandemic in Kenya based on serological and PCR-test data.Ojal J Brand SPC Were V Okiro EA Kombe IK Mburu C Aziza R Ogero M Agweyu A Warimwe GM Uyoga S Adetifa IMO Scott JAG Otieno E Ochola-Oyier LI Agoti CN Kasera K Amoth P Mwangangi M Aman R Ng'ang'a W Tsofa B Bejon P Barasa E Keeling MJ Nokes DJ
Wellcome Open Res, (2022). 6:127

Epidemiology of COVID-19 infections on routine polymerase chain reaction (PCR) and serology testing in Coastal Kenya.Nyagwange J Ndwiga L Muteru K Wamae K Tuju J Testing Team C Kutima B Gitonga J Karanja H Mugo D Kasera K Amoth P Murunga N Babu L Otieno E Githinji G Nokes DJ Tsofa B Orindi B Barasa E Warimwe G Agoti CN Bejon P Ochola-Oyier LI
Wellcome Open Res, (2022). 7:69

Efficiency of transplacental transfer of respiratory syncytial virus (RSV) specific antibodies among pregnant women in Kenya.Nyiro JU Bukusi E Mwaengo D Nyaguara A Nyawanda B Otieno N Bigogo G Murunga N Widdowson MA Verani JR Chaves SS Mwangudza H Odundo C Berkley JA Nokes DJ Munywoki PK
Wellcome Open Res, (2022). 7:43

TRUE-1: Trial of Repurposed Unithiol for snakebite Envenoming phase 1 (safety, tolerability, pharmacokinetics and pharmacodynamics in healthy Kenyan adults).Abouyannis M FitzGerald R Ngama M Mwangudzah H Nyambura YK Ngome S Riako D Babu L Lewa F Else L Dily Penchala S Orindi B Mumba N Kalama B Ndungu FM Adetifa I Khoo S Lalloo DG Casewell NR Hamaluba M
Wellcome Open Res, (2022). 7:90

Mortality in rural coastal Kenya measured using the Kilifi Health and Demographic Surveillance System: a 16-year descriptive analysis.Otiende M Bauni E Nyaguara A Amadi D Nyundo C Tsory E Walumbe D Kinuthia M Kihuha N Kahindi M Nyutu G Moisi J Deribew A Agweyu A Marsh K Tsofa B Bejon P Bottomley C Williams TN Scott JAG
Wellcome Open Res, (2021). 6:327

Children's Oxygen Administration Strategies And Nutrition Trial (COAST-Nutrition): a protocol for a phase II randomised controlled trial.Kiguli S Olopot-Olupot P Alaroker F Engoru C Opoka RO Tagoola A Hamaluba M Mnjalla H Mpoya A Mogaka C Nalwanga D Nabawanuka E Nokes J Nyaigoti C Briend A van Woensel JBM Grieve R Sadique Z Williams TN Thomas K Harrison DA Rowan K Maitland K
Wellcome Open Res, (2021). 6:221

Whole genome sequencing of two human rhinovirus A types (A101 and A15) detected in Kenya, 2016-2018.Luka MM Kamau E de Laurent ZR Morobe JM Alii LK Nokes DJ Agoti CN
Wellcome Open Res, (2021). 6:178

Haplotype heterogeneity and low linkage disequilibrium reduce reliable prediction of genotypes for the ÔÇæalpha (3.7I) form of alpha-thalassaemia using genome-wide microarray data.Ndila CM Nyirongo V Macharia AW Jeffreys AE Rowlands K Hubbart C Busby GBJ Band G Harding RM Rockett KA Williams TN Malaria GENConsortium
Wellcome Open Res, (2020). 5:287

Mortality during and following hospital admission among school-aged children: a cohort study.Ngari MM Obiero C Mwangome MK Nyaguara A Mturi N Murunga S Otiende M Iversen PO Fegan GW Walson JL Berkley JA
Wellcome Open Res, (2020). 5:234