Tom Williams

The Epidemiology of Sickle Cell Disease in Sub-Saharan Africa: Current Knowledge and Gaps to be Filled.Ranque B Tshilolo L Williams TN
Am J Hematol, (2026). 101 Suppl 1:5-16

Nasopharyngeal Microbiome Composition and its Clinical Correlates in Children Hospitalized with Severe Pneumonia in East Africa.Makori TO Gicheru ET Mburu MW Sada MS Nyawa O Mutunga M Lewa C Cheruiyot R Kiguli S Olupot-Olupot P Muhindo R Mogaka C Williams TN Agoti CN Maitland K Sande CJ
J Infect Dis, (2026). :

A cost-consequence analysis of the children's administration oxygenation strategies trial (COAST) in severe pneumonia.Carroll OU Grieve R Kiguli S Olupot-Olupot P Opoka RO Alaroker F Tagoola A Hamaluba M Nabawanuka E Nalwanga D Williams TN Thomas K Harrison DA Mouncey P Giallongo E Rowan K Maitland K Sadique Z
PLOS Glob Public Health, (2026). 6:e0005654

Hydroxyurea pharmacokinetics in children with sickle cell anemia across different global populations.Power-Hays A McElhinney KE Williams TN Mochamah G Olupot-Olupot P Paasi G Reid ME Rankine-Mullings AE Opoka RO John CC McGann PT Quinn CT Punt NC Smart LR Stuber SE Latham TS Vinks AA Ware RE
Blood Adv, (2026). 10:418-427

Plasma folate dynamics in Plasmodium falciparum-infected African children treated with artemisinin combination therapy and single low-dose primaquine or placebo.Ajayi S Onyamboko MA Olupot-Olupot P Ayuen DS Chimjinda N Taya C Williams TN Uyoga S Maitland K Fanello C Day NPJ Mukaka M Taylor WRJ
Malar J, (2025). 24:342

Single low dose primaquine to block the transmission of Plasmodium falciparum-proposed stand-alone and ACT-adapted regimens.Taylor WRJ Olupot-Olupot P Onyamboko MA Chimjinda N Taya C Pouplin JNN Williams TN Maitland K Fanello CA Day NPJ Tarning J White NJ Mukaka M
BMC Med, (2025). 23:397

Early weaning from oxygen therapy in African children with severe pneumonia.Maitland K Giallongo E Hamaluba M Alaroker F Opoka RO Tagoola A Nalwanga D Nabawanuka E Okiror W Nakuya M Aromut D Williams TN Thomas K Harrison DA Mouncey P Bush A Fraser JF Rowan K Olupot-Olupot P Kiguli S Coast trial group
BMC Med, (2025). 23:366

OSBPL11 is an African-specific locus associated with 25-hydroxyvitamin D concentrations and cardiometabolic health.Mogire RM Muriuki JM Bayimenye RF Mentzer AJ Chong A Gouveia MH Bentley AR Band G King'ori P Mitchell R Webb EL Sengupta D Ekunwe L Ndungu FM Morovat A Macharia AW Cutland CL Hemani G Sirima SB Ramsay M Figueiredo CA Prentice AM Madhi SA Raffield LM Sandhu MS Bejon P Smith GD Elliott AM Williams TN Rotimi C Bourne CR Burgett A Adeyemo A Atkinson SH
medRxiv, (2025). :

Comparing HemoCue(R) and Quantitative Buffy Coat(R) and Coulter Counter-measured haemoglobin concentrations in African children with acute uncomplicated malaria: a Bland-Altman analysis.Ayuen DS Olupot-Olupot P Muhindo R Onyamboko MA Ajayi S Chimjinda N Taya C Uyoga S Williams TN Maitland K Fanello C Day NPJ Taylor WR Mukaka M
Malar J, (2025). 24:77

Malaria prophylaxis in sickle cell anaemia: some answers, more questions.Williams TN Ware RE
Lancet Infect Dis, (2025). 25:601-602

Infections in sickle cell disease.Scourfield LEA Nardo-Marino A Williams TN Rees DC
Haematologica, (2025). 110:546-561

Relation Between the Dantu Blood Group Variant and Bacteremia in Kenyan Children: A Population-Based Case-Control Study.Kariuki SN Gilchrist JJ Uyoga S Macharia A Makale J Rayner JC Williams TN
J Infect Dis, (2025). 231:e10-e16

Azithromycin in severe malaria bacterial co-infection in African children (TABS-PKPD): a phase II randomised controlled trial.Connon R Olupot-Olupot P Pistorius AMA Okiror W Ssenyondo T Muhindo R Uyoga S Mpoya A Williams TN Gibb DM Walker AS Ter Heine R George EC Maitland K
BMC Med, (2024). 22:516

SEVUparin as a potential Adjunctive Treatment in children with severe malaria: A phase I trial safety and dose finding trial (SEVUSMAART).Maitland K Hamaluba M Obonyo N Oguda E Mogoka C Williams TN Chaponda M Miti S Kamavu LK Jonathan Gwasupika J Connon R Gibb DM Dondorp A Day N White N Walker AS George EC Severe Malaria in African Children AResearch Trials consortium
Wellcome Open Res, (2024). 8:484

A Phase I trial of Non-invasive Ventilation and seizure prophylaxis with levetiracetam In Children with Cerebral Malaria Trial (NOVICE-M Trial).Maitland K Obonyo N Hamaluba M Ogoda E Mogaka C Williams TN Newton C Kariuki SM Gibb DM Walker AS Connon R George EC
Wellcome Open Res, (2024). 9:281

Nutritional supplementation in children with severe pneumonia in Uganda and Kenya (COAST-Nutrition): a phase 2 randomised controlled trial.Kiguli S Olupot-Olupot P Hamaluba M Giallongo E Thomas K Alaroker F Opoka RO Tagoola A Oyella S Nalwanga D Nabawanuka E Okiror W Nakuya M Amorut D Muhindo R Ayub Mpoya Mnjalla H Oguda E Williams TN Harrison DA Rowan K Briend A Maitland K
EClinicalMedicine, (2024). 72:102640

Hydroxyurea dose optimisation for children with sickle cell anaemia in sub-Saharan Africa (REACH): extended follow-up of a multicentre, open-label, phase 1/2 trial.Aygun B Lane A Smart LR Santos B Tshilolo L Williams TN Olupot-Olupot P Stuber SE Tomlinson G Latham T Ware RE Reach Investigators
Lancet Haematol, (2024). 11:e425-e435

Reducing transfusion utilization for children with sickle cell anemia in sub-Saharan Africa with hydroxyurea: Analysis from the phase I/II REACH trial.Power-Hays A Tomlinson GA Tshilolo L Santos B Williams TN Olupot-Olupot P Smart LR Aygun B Lane A Stuber SE Latham T Ware RE
Am J Hematol, (2024). 99:625-632

Dantu Blood Group Erythrocytes Form Large Plasmodium falciparum Rosettes Less Commonly.Carlier MSA Nyamu W Makale J Williams TN Rowe JA Kariuki SN
Am J Trop Med Hyg, (2024). 110:436-443

Impact of COVID-19 on mortality in coastal Kenya: a longitudinal open cohort study.Otiende M Nyaguara A Bottomley C Walumbe D Mochamah G Amadi D Nyundo C Kagucia EW Etyang AO Adetifa IMO Brand SPC Maitha E Chondo E Nzomo E Aman R Mwangangi M Amoth P Kasera K Ng'ang'a W Barasa E Tsofa B Mwangangi J Bejon P Agweyu A Williams TN Scott JAG
Nat Commun, (2023). 14:6879