Williams TN

Malaria in patients with sickle cell anemia: burden, risk factors, and outcome at the outpatient clinic and during hospitalization.Makani J, Komba AN, Cox SE, Oruo J, Mwamtemi K, Kitundu J, Magesa P, Rwezaula S, Meda E, Mgaya J, Pallangyo K, Okiro E, Muturi D, Newton CR, Fegan G, Marsh K, Williams TN
Blood, (2010). 115:215-20

NFKBIZ polymorphisms and susceptibility to pneumococcal disease in European and African populations.Chapman SJ, Khor CC, Vannberg FO, Rautanen A, Segal S, Moore CE, Davies RJ, Day NP, Peshu N, Crook DW, Berkley JA, Williams TN, Scott JA, Hill AV
Genes Immun, (2010). 11:319-25

Preventable deaths in sickle-cell anaemia in African children - Authors' reply.Williams TN, Uyoga S, Macharia A, Sharif SK, Scott JA
Lancet, (2010). 375:461

Bacteraemia in Kenyan children with sickle-cell anaemia: a retrospective cohort and case-control study.Williams TN, Uyoga S, Macharia A, Ndila C, McAuley CF, Opi DH, Mwarumba S, Makani J, Komba A, Ndiritu MN, Sharif SK, Marsh K, Berkley JA, Scott JA
Lancet, (2009). 374:1364-70

Transmission-dependent tolerance to multiclonal Plasmodium falciparum infection.Farnert A, Williams TN, Mwangi TW, Ehlin A, Fegan G, Macharia A, Lowe BS, Montgomery SM, Marsh K
J Infect Dis, (2009). 200:1166-75

An observational study of children with sickle cell disease in Kilifi, Kenya.Sadarangani M, Makani J, Komba AN, Ajala-Agbo T, Newton CR, Marsh K, Williams TN
Br J Haematol, (2009). 146:675-82

HIV infection, malnutrition, and invasive bacterial infection among children with severe malaria.Berkley JA, Bejon P, Mwangi T, Gwer S, Maitland K, Williams TN, Mohammed S, Osier F, Kinyanjui S, Fegan G, Lowe BS, English M, Peshu N, Marsh K, Newton CR
Clin Infect Dis, (2009). 49:336-43

Epidemiological studies of the 'non-specific effects' of vaccines: I--data collection in observational studies.Fine PE, Williams TN, Aaby P, Kallander K, Moulton LH, Flanagan KL, Smith PG, Benn CS
Trop Med Int Health, (2009). 14:969-76

Homozygosity and risk of childhood death due to invasive bacterial disease.Lyons EJ, Amos W, Berkley JA, Mwangi I, Shafi M, Williams TN, Newton CR, Peshu N, Marsh K, Scott JA, Hill AV
BMC Med Genet, (2009). 10:55

Malaria as a cause of morbidity and mortality in children with homozygous sickle cell disease on the coast of Kenya.Komba AN, Makani J, Sadarangani M, Ajala-Agbo T, Berkley JA, Newton CR, Marsh K, Williams TN
Clin Infect Dis, (2009). 49:216-22

Genome-wide and fine-resolution association analysis of malaria in West Africa.Jallow M, Teo YY, Small KS, Rockett KA, Deloukas P, Clark TG, Kivinen K, Bojang KA, Conway DJ, Pinder M, Sirugo G, Sisay-Joof F, Usen S, Auburn S, Bumpstead SJ, Campino S, Coffey A, Dunham A, Fry AE, Green A, Gwilliam R, Hunt SE, Inouye M, Jeffreys AE, Mendy A, Palotie A, Potter S, Ragoussis J, Rogers J, Rowlands K, Somaskantharajah E, Whittaker P, Widden C, Donnelly P, Howie B, Marchini J, Morris A, SanJoaquin M, Achidi EA, Agbenyega T, Allen A, Amodu O, Corran P, Djimde A, Dolo A, Doumbo OK, Drakeley C, Dunstan S, Evans J, Farrar J, Fernando D, Hien TT, Horstmann RD, Ibrahim M, Karunaweera N, Kokwaro G, Koram KA, Lemnge M, Makani J, Marsh K, Michon P, Modiano D, Molyneux ME, Mueller I, Parker M, Peshu N, Plowe CV, Puijalon O, Reeder J, Reyburn H, Riley EM, Sakuntabhai A, Singhasivanon P, Sirima S, Tall A, Taylor TE, Thera M, Troye-Blomberg M, Williams TN, Wilson M, Kwiatkowski DP
Nat Genet, (2009). 41:657-65

Positive selection of a CD36 nonsense variant in sub-Saharan Africa, but no association with severe malaria phenotypes.Fry AE, Ghansa A, Small KS, Palma A, Auburn S, Diakite M, Green A, Campino S, Teo YY, Clark TG, Jeffreys AE, Wilson J, Jallow M, Sisay-Joof F, Pinder M, Griffiths MJ, Peshu N, Williams TN, Newton CR, Marsh K, Molyneux ME, Taylor TE, Koram KA, Oduro AR, Rogers WO, Rockett KA, Sabeti PC, Kwiatkowski DP
Hum Mol Genet, (2009). 18:2683-92

Risk factors for high cerebral blood flow velocity and death in Kenyan children with Sickle Cell Anaemia: role of haemoglobin oxygen saturation and febrile illness.Makani J, Kirkham FJ, Komba A, Ajala-Agbo T, Otieno G, Fegan G, Williams TN, Marsh K, Newton CR
Br J Haematol, (2009). 145:529-32

Tumor necrosis factor and lymphotoxin-alpha polymorphisms and severe malaria in African populations.Clark TG, Diakite M, Auburn S, Campino S, Fry AE, Green A, Richardson A, Small K, Teo YY, Wilson J, Jallow M, Sisay-Joof F, Pinder M, Griffiths MJ, Peshu N, Williams TN, Marsh K, Molyneux ME, Taylor TE, Rockett KA, Kwiatkowski DP
J Infect Dis, (2009). 199:569-75

Human genetic resistance to malaria.Williams TN
Adv Exp Med Biol, (2009). 634:243-53

Lack of association of interferon regulatory factor 1 with severe malaria in affected child-parental trio studies across three African populations.Mangano VD, Clark TG, Auburn S, Campino S, Diakite M, Fry AE, Green A, Richardson A, Jallow M, Sisay-Joof F, Pinder M, Griffiths MJ, Newton C, Peshu N, Williams TN, Marsh K, Molyneux ME, Taylor TE, Modiano D, Kwiatkowski DP, Rockett KA
PLoS One, (2009). 4:e4206

Population Genetics and Global Health Burden.Weatherall DJ, Williams TN
Disorders of Hemoglobin, (2009). :

Survival and haematological recovery of children with severe malaria transfused in accordance to WHO guidelines in Kilifi, Kenya.Akech SO, Hassall O, Pamba A, Idro R, Williams TN, Newton CR, Maitland K
Malar J, (2008). 7:256

Acquisition of growth-inhibitory antibodies against blood-stage Plasmodium falciparum.McCallum FJ, Persson KE, Mugyenyi CK, Fowkes FJ, Simpson JA, Richards JS, Williams TN, Marsh K, Beeson JG
PLoS One, (2008). 3:e3571

Association of the GNAS locus with severe malaria.Auburn S, Diakite M, Fry AE, Ghansah A, Campino S, Richardson A, Jallow M, Sisay-Joof F, Pinder M, Griffiths MJ, Peshu N, Williams TN, Marsh K, Molyneux ME, Taylor TE, Koram KA, Oduro AR, Rogers WO, Rockett KA, Haldar K, Kwiatkowski DP
Hum Genet, (2008). 124:499-506