Publications

Epidemiology and Demography

Human Rhinovirus B and C Genomes from Rural Coastal Kenya.Agoti CN, Kiyuka PK, Kamau E, Munywoki PK, Bett A, van der Hoek L, Kellam P, Nokes DJ, Cotten M
Genome Announc, (2016). 4:

Age, Spatial, and Temporal Variations in Hospital Admissions with Malaria in Kilifi County, Kenya: A 25-Year Longitudinal Observational Study.Mogeni P, Williams TN, Fegan G, Nyundo C, Bauni E, Mwai K, Omedo I, Njuguna P, Newton CR, Osier F, Berkley JA, Hammitt LL, Lowe B, Mwambingu G, Awuondo K, Mturi N, Peshu N, Snow RW, Noor A, Marsh K, Bejon P
PLoS Med, (2016). 13:e1002047

Human metapneumovirus epidemiological and evolutionary patterns in Coastal Kenya, 2007-11.Owor BE, Masankwa GN, Mwango LC, Njeru RW, Agoti CN, Nokes DJ
BMC Infect Dis, (2016). 16:301

Polymorphism in a lincRNA Associates with a Doubled Risk of Pneumococcal Bacteremia in Kenyan Children.Kenyan Bacteraemia Study Group, Wellcome Trust Case Control Consortium, Rautanen A, Pirinen M, Mills TC, Rockett KA, Strange A, Ndungu AW, Naranbhai V, Gilchrist JJ, Bellenguez C, Freeman C, Band G, Bumpstead SJ, Edkins S, Giannoulatou E, Gray E, Dronov S, Hunt SE, Langford C, Pearson RD, Su Z, Vukcevic D, Macharia AW, Uyoga S, Ndila C, Mturi N, Njuguna P, Mohammed S, Berkley JA, Mwangi I, Mwarumba S, Kitsao BS, Lowe BS, Morpeth SC, Khandwalla I, Kilifi Bacteraemia Surveillance Group, Blackwell JM, Bramon E, Brown MA, Casas JP, Corvin A, Duncanson A, Jankowski J, Markus HS, Mathew CG, Palmer CNA, Plomin R, Sawcer SJ, Trembath RC, Viswanathan AC, Wood NW, Deloukas P, Peltonen L, Williams TN, Scott JAG, Chapman SJ, Donnelly P, Hill AVS, Spencer CCA
Am J Hum Genet, (2016). 98:1092-1100

The Malaria-High Blood Pressure Hypothesis.Etyang AO, Smeeth L, Cruickshank JK, Scott JA
Circ Res, (2016). 119:36-40

Influenza activity in Kenya, 2007-2013: timing, association with climatic factors, and implications for vaccination campaigns.Emukule GO, Mott JA, Spreeuwenberg P, Viboud C, Commanday A, Muthoka P, Munywoki PK, Nokes DJ, van der Velden K, Paget JW
Influenza Other Respir Viruses, (2016). 10:375-85

Building Learning Health Systems to Accelerate Research and Improve Outcomes of Clinical Care in Low- and Middle-Income Countries.English M, Irimu G, Agweyu A, Gathara D, Oliwa J, Ayieko P, Were F, Paton C, Tunis S, Forrest CB
PLoS Med, (2016). 13:e1001991

Sickle Cell Disease in Sub-Saharan Africa.Williams TN
Hematol Oncol Clin North Am, (2016). 30:343-58

Molecular Evolutionary Dynamics of Respiratory Syncytial Virus Group A in Recurrent Epidemics in Coastal Kenya.Otieno JR, Agoti CN, Gitahi CW, Bett A, Ngama M, Medley GF, Cane PA, Nokes DJ
J Virol, (2016). 90:4990-5002

Effect of Haemophilus influenzae type b vaccination without a booster dose on invasive H influenzae type b disease, nasopharyngeal carriage, and population immunity in Kilifi, Kenya: a 15-year regional surveillance study.Hammitt LL, Crane RJ, Karani A, Mutuku A, Morpeth SC, Burbidge P, Goldblatt D, Kamau T, Sharif S, Mturi N, Scott JA
Lancet Glob Health, (2016). 4:e185-94

Red blood cell complement receptor one level varies with Knops blood group, alpha(+)thalassaemia and age among Kenyan children.Opi DH, Uyoga S, Orori EN, Williams TN, Rowe JA
Genes Immun, (2016). 17:171-8

Increased adhesion of Plasmodium falciparum infected erythrocytes to ICAM-1 in children with acute intestinal injury.Church JA, Nyamako L, Olupot-Olupot P, Maitland K, Urban BC
Malar J, (2016). 15:54

Invasive Group A Streptococcus Infection among Children, Rural Kenya.Seale AC, Davies MR, Anampiu K, Morpeth SC, Nyongesa S, Mwarumba S, Smeesters PR, Efstratiou A, Karugutu R, Mturi N, Williams TN, Scott JA, Kariuki S, Dougan G, Berkley JA
Emerg Infect Dis, (2016). 22:224-32

Environmental Correlation Analysis for Genes Associated with Protection against Malaria.Mackinnon MJ, Ndila C, Uyoga S, Macharia A, Snow RW, Band G, Rautanen A, Rockett KA, Kwiatkowski DP, Williams TN
Mol Biol Evol, (2016). 33:1188-204

Observed and expected frequencies of structural hemoglobin variants in newborn screening surveys in Africa and the Middle East: deviations from Hardy-Weinberg equilibrium.Piel FB, Adamkiewicz TV, Amendah D, Williams TN, Gupta S, Grosse SD
Genet Med, (2016). 18:265-74

Hydroxyurea Therapy for Children With Sickle Cell Anemia in Sub-Saharan Africa: Rationale and Design of the REACH Trial.McGann PT, Tshilolo L, Santos B, Tomlinson GA, Stuber S, Latham T, Aygun B, Obaro SK, Olupot-Olupot P, Williams TN, Odame I, Ware RE, REACH Investigators
Pediatr Blood Cancer, (2016). 63:98-104

Host Genetics.Williams TN
Advances in Malaria research, (2016). :

Infectious disease and health systems modelling for local decision making to control neglected tropical diseases.Hollingsworth TD, Langley I, Nokes DJ, Macpherson EE, McGivern G, Adams ER, Bockarie MJ, Mortimer K, Reimer LJ, Squire B, Torr SJ, Medley GF
BMC Proc, (2015). 9:S6

Erratum to "Mechanistic Studies of the Negative Epistatic Malaria-protective Interaction Between Sickle Cell Trait and alpha(+)thalassemia" [EBioMedicine 1 (2014) 29-36].Opi DH, Ochola LB, Tendwa M, Siddondo BR, Ocholla H, Fanjo H, Ghumra A, Ferguson DJ, Rowe JA, Williams TN
EBioMedicine, (2015). 2:1001

Transfusion and Treatment of severe anaemia in African children (TRACT): a study protocol for a randomised controlled trial.Mpoya A, Kiguli S, Olupot-Olupot P, Opoka RO, Engoru C, Mallewa M, Chimalizeni Y, Kennedy N, Kyeyune D, Wabwire B, M'Baya B, Bates I, Urban B, von Hensbroek MB, Heyderman R, Thomason MJ, Uyoga S, Williams TN, Gibb DM, George EC, Walker AS, Maitland K
Trials, (2015). 16:593