Publications

Biosciences

Systemic inflammation and metabolic disturbances underlie inpatient mortality among ill children with severe malnutrition.Wen B, Njunge JM, Bourdon C, Gonzales GB, Gichuki BM, Lee D, Wishart DS, Ngari M, Chimwezi E, Thitiri J, Mwalekwa L, Voskuijl W, Berkley JA, Bandsma RH
Sci Adv, (2022). 8:eabj6779

Readiness of the Kenyan public health sector to provide pre-referral care for severe paediatric malaria.Amboko B, Machini B, Githuka G, Bejon P, Zurovac D, Snow RW
Trop Med Int Health, (2022). 27:330-336

Malaria hospitalisation in East Africa: age, phenotype and transmission intensity.Kamau A, Paton RS, Akech S, Mpimbaza A, Khazenzi C, Ogero M, Mumo E, Alegana VA, Agweyu A, Mturi N, Mohammed S, Bigogo G, Audi A, Kapisi J, Sserwanga A, Namuganga JF, Kariuki S, Otieno NA, Nyawanda BO, Olotu A, Salim N, Athuman T, Abdulla S, Mohamed AF, Mtove G, Reyburn H, Gupta S, Lourenco J, Bejon P, Snow RW
BMC Med, (2022). 20:28

Controlled human malaria infection (CHMI) outcomes in Kenyan adults is associated with prior history of malaria exposure and anti-schizont antibody response.Kapulu MC, Kimani D, Njuguna P, Hamaluba M, Otieno E, Kimathi R, Tuju J, Sim BKL, CHMI-SIKA Study Team
BMC Infect Dis, (2022). 22:86

Distinct kinetics of antibodies to 111 Plasmodium falciparum proteins identifies markers of recent malaria exposure.Yman V, Tuju J, White MT, Kamuyu G, Mwai K, Kibinge N, Asghar M, Sundling C, Sonden K, Murungi L, Kiboi D, Kimathi R, Chege T, Chepsat E, Kiyuka P, Nyamako L, Osier FHA, Farnert A
Nat Commun, (2022). 13:331

Characterization of Anopheles gambiae D7 salivary proteins as markers of human-mosquito bite contact.Oseno B, Marura F, Ogwang R, Muturi M, Njunge J, Nkumama I, Mwakesi R, Mwai K, Rono MK, Mwakubambanya R, Osier F, Tuju J
Parasit Vectors, (2022). 15:11

Comparative performance of WANTAI ELISA for total immunoglobulin to receptor binding protein and an ELISA for IgG to spike protein in detecting SARS-CoV-2 antibodies in Kenyan populations.Nyagwange J, Kutima B, Mwai K, Karanja HK, Gitonga JN, Mugo D, Uyoga S, Tuju J, Ochola-Oyier LI, Ndungu F, Bejon P, Agweyu A, Adetifa IMO, Scott JAG, Warimwe GM
J Clin Virol, (2022). 146:105061

Malaria protection due to sickle haemoglobin depends on parasite genotype.Band G, Leffler EM, Jallow M, Sisay-Joof F, Ndila CM, Macharia AW, Hubbart C, Jeffreys AE, Rowlands K, Nguyen T, Goncalves S, Ariani CV, Stalker J, Pearson RD, Amato R, Drury E, Sirugo G, d'Alessandro U, Bojang KA, Marsh K, Peshu N, Saelens JW, Diakite M, Taylor SM, Conway DJ, Williams TN, Rockett KA, Kwiatkowski DP
Nature, (2022). 602:106-111

Neurological impairment and disability in children in rural Kenya.Abuga JA, Kariuki SM, Abubakar A, Nyundo C, Kinyanjui SM, Van Hensbroek MB, Newton CR
Dev Med Child Neurol, (2022). 64:347-356

Hepcidin regulation in Kenyan children with severe malaria and non-typhoidal Salmonella bacteremia.Abuga KM, Muriuki JM, Uyoga SM, Mwai K, Makale J, Mogire RM, Macharia AW, Mohammed S, Muthumbi E, Mwarumba S, Mturi N, Bejon P, Scott JAG, Nairz M, Williams TN, Atkinson SH
Haematologica, (2022). 107:1589-1598

Seroprevalence of Antibodies to Severe Acute Respiratory Syndrome Coronavirus 2 Among Healthcare Workers in Kenya.Etyang AO, Lucinde R, Karanja H, Kalu C, Mugo D, Nyagwange J, Gitonga J, Tuju J, Wanjiku P, Karani A, Mutua S, Maroko H, Nzomo E, Maitha E, Kamuri E, Kaugiria T, Weru J, Ochola LB, Kilimo N, Charo S, Emukule N, Moracha W, Mukabi D, Okuku R, Ogutu M, Angujo B, Otiende M, Bottomley C, Otieno E, Ndwiga L, Nyaguara A, Voller S, Agoti CN, Nokes DJ, Ochola-Oyier LI, Aman R, Amoth P, Mwangangi M, Kasera K, Ng'ang'a W, Adetifa IMO, Wangeci Kagucia E, Gallagher K, Uyoga S, Tsofa B, Barasa E, Bejon P, Scott JAG, Agweyu A, Warimwe GM
Clin Infect Dis, (2022). 74:288-293

The global burden of Chikungunya fever among children: A systematic literature review and meta-analysis.Nyamwaya DK, Thumbi SM, Bejon P, Warimwe GM, Mokaya J
PLOS Global Public Health, (2022). 2:e0000914

Revealing the extent of the first wave of the COVID-19 pandemic in Kenya based on serological and PCR-test data.Ojal J, Brand SPC, Were V, Okiro EA, Kombe IK, Mburu C, Aziza R, Ogero M, Agweyu A, Warimwe GM, Uyoga S, Adetifa IMO, Scott JAG, Otieno E, Ochola-Oyier LI, Agoti CN, Kasera K, Amoth P, Mwangangi M, Aman R, Ng'ang'a W, Tsofa B, Bejon P, Barasa E, Keeling MJ, Nokes DJ
Wellcome Open Res, (2021). 6:127

Barriers to access and utilization of healthcare by children with neurological impairments and disability in low-and middle-income countries: a systematic review.Mwangi LW, Abuga JA, Cottrell E, Kariuki SM, Kinyanjui SM, Newton CR
Wellcome Open Res, (2021). 6:61

Toll-Like Receptor-Induced Immune Responses During Early Childhood and Their Associations With Clinical Outcomes Following Acute Illness Among Infants in Sub-Saharan Africa.Uebelhoer LS, Gwela A, Thiel B, Nalukwago S, Mukisa J, Lwanga C, Getonto J, Nyatichi E, Dena G, Makazi A, Mwaringa S, Mupere E, Berkley JA, Lancioni CL
Front Immunol, (2021). 12:748996

10-year longitudinal study of malaria in children: Insights into acquisition and maintenance of naturally acquired immunity.Addy JWG, Bediako Y, Ndungu FM, Valetta JJ, Reid AJ, Mwacharo J, Ngoi JM, Wambua J, Otieno E, Musyoki J, Said K, Berriman M, Marsh K, Bejon P, Recker M, Langhorne J
Wellcome Open Res, (2021). 6:79

Determinants of improvement trends in health workers' compliance with outpatient malaria case-management guidelines at health facilities with available "test and treat" commodities in Kenya.Amboko B, Stepniewska K, Malla L, Machini B, Bejon P, Snow RW, Zurovac D
PLoS One, (2021). 16:e0259020

Quantifying previous SARS-CoV-2 infection through mixture modelling of antibody levels.Bottomley C, Otiende M, Uyoga S, Gallagher K, Kagucia EW, Etyang AO, Mugo D, Gitonga J, Karanja H, Nyagwange J, Adetifa IMO, Agweyu A, Nokes DJ, Warimwe GM, Scott JAG
Nat Commun, (2021). 12:6196

Anti-Severe Acute Respiratory Syndrome Coronavirus 2 Immunoglobulin G Antibody Seroprevalence Among Truck Drivers and Assistants in Kenya.Kagucia EW, Gitonga JN, Kalu C, Ochomo E, Ochieng B, Kuya N, Karani A, Nyagwange J, Karia B, Mugo D, Karanja HK, Tuju J, Mutiso A, Maroko H, Okubi L, Maitha E, Ajuck H, Mukabi D, Moracha W, Bulimu D, Andanje N, Aman R, Mwangangi M, Amoth P, Kasera K, Ng'ang'a W, Nyaguara A, Voller S, Otiende M, Bottomley C, Agoti CN, Ochola-Oyier LI, Adetifa IMO, Etyang AO, Gallagher KE, Uyoga S, Barasa E, Bejon P, Tsofa B, Agweyu A, Warimwe GM, Scott JAG, Magarini Sub-County TDA SARS-CoV-2 Serosurveillance Team, The Busia County TDA SARS-CoV-Serosurveillance Team
Open Forum Infect Dis, (2021). 8:ofab314

Malaria vaccine roller coaster.Nkumama IN, Osier FHA
Nat Microbiol, (2021). 6:1345-1346