Publications

Biosciences

Linking Cerebral Malaria Pathogenesis to APOE-Mediated Amyloidosis: Observations and Hypothesis.Kioko M Mwangi S Njunge JM Berkley JA Bejon P Abdi AI
Mol Neurobiol, (2025). 62:1720-1725

Malaria Chemotherapeutics What Next for Africa.Ochola L Gitaka J Kanoi B Kimani CN Akala HM Alfred MO Ochola-Oyier LI Ogutu B
Advanced Therapeutics, (2025). 8:2400453

Comparative performance of the InBios SCoV-2 Detect (TM) IgG ELISA and the in-house KWTRP ELISA in detecting SARS-CoV-2 spike IgG antibodies in Kenyan populations.Kutima B Kagucia EW Mwai K Kimani M Sigilai A Mugo D Karanja H Gitonga JN Karani A Akech D Toroitich M Karia B Tuju J Ziraba AK Bigogo G Ochieng C Onyango C Lidechi S Munywoki PK Uyoga S Adetifa IMO Oyier LIO Bejon P Scott JAG Agweyu A Warimwe GM Nyagwange J Kenya Sars-CoV-Serology Consortium
Wellcome Open Res, (2024). 9:349

Evaluation of population immunity against SARS-CoV-2 variants, EG.5.1, FY.4, BA.2.86, JN.1, JN.1.4, and KP.3.1.1 using samples from two health demographic surveillance systems in Kenya.Lugano D Kutima B Kimani M Sigilai A Gitonga J Karani A Akech D Karia B Ziraba AK Maina A Lambisia A Omuoyo D Mugo D Lucinde R Owuor S Konyino G Newman J Bailey D Nduati E Githinji G Agoti CN Bejon P Scott JAG Agweyu A Kagucia W Warimwe GM Sande C Ochola-Oyier LI Nyagwange J
BMC Infect Dis, (2024). 24:1474

Identification of complex Plasmodium falciparum genetic backgrounds circulating in Africa: a multicountry genomic epidemiology analysis.Miotto O Amambua-Ngwa A Amenga-Etego LN Abdel Hamid MM Adam I Aninagyei E Apinjoh T Awandare GA Bejon P Bertin GI Bouyou-Akotet M Claessens A Conway DJ D'Alessandro U Diakite M Djimde A Dondorp AM Duffy P Fairhurst RM Fanello CI Ghansah A Ishengoma DS Lawniczak M Maiga-Ascofare O Auburn S Rosanas-Urgell A Wasakul V White NFD Harrott A Almagro-Garcia J Pearson RD Goncalves S Ariani C Bozdech Z Hamilton WL Simpson V Kwiatkowski DP
Lancet Microbe, (2024). 5:100941

Prospective clinical surveillance for severe acute respiratory illness and COVID-19 vaccine effectiveness in Kenyan hospitals during the COVID-19 pandemic.Lucinde RK Gathuri H Isaaka L Ogero M Mumelo L Kimego D Mbevi G Wanyama C Otieno EO Mwakio S Saisi M Isinde E Oginga IN Wachira A Manuthu E Kariuki H Nyikuli J Wekesa C Otedo A Bosire H Okoth SB Ongalo W Mukabi D Lusamba W Muthui B Adembesa I Mithi C Sood M Ahmed N Gituma B Giabe M Omondi C Aman R Amoth P Kasera K Were F Nganga W Berkley JA Tsofa B Mwangangi J Bejon P Barasa E English M Scott JAG Akech S Kagucia EW Agweyu A Etyang AO
BMC Infect Dis, (2024). 24:1246

ONT sequencing identifies a high prevalence of crt sensitive, triple mutant dhfr and single mutant dhps parasites within an ANC population in Nigeria.Adegbola AJ Ndwiga L Wamae K Osoti V Bolaji OO Bejon P Ochola-Oyier LI
Front Genet, (2024). 15:1470156

Molecular xenomonitoring reveals Anopheles funestus and An. rivulorum as the primary vectors of lymphatic filariasis in coastal Kenya.Bartilol B Babu L Garama K Karisa J Kamau A Mwandawiro C Wanjiku C Mbogo C Maia M Mwangangi J Rono MK
Parasit Vectors, (2024). 17:425

A cross-sectional analysis identifies a low prevalence of Plasmodium ovale species infections in symptomatic and asymptomatic individuals in Kilifi county, Kenya.Akinyi MY Chifwete M Ndwiga L Kimenyi KM Osoti V Ochola-Oyier LI
Wellcome Open Res, (2024). 7:207

Mosquitocidal efficacy and pharmacokinetics of single-dose ivermectin versus three-day dose regimen for malaria vector control compared with albendazole and no treatment: An open-label randomized controlled trial.Kamau Y Tuwei M Wanjiku C Ominde K Ngama M Karisa J Babu L Muturi M Mwatasa M Adetifa J Kern C Duthaler U Hammann F Rabinovich R Chaccour C Maia MF
Int J Infect Dis, (2024). 148:107236

Antibodies to PfEMP1 and variant surface antigens: Protection after controlled human malaria infection in semi-immune Kenyan adults.Kinyua AW Turner L Kimingi HW Mwai K Mwikali K Andisi C Sim BKL Bejon P Kapulu MC Kinyanjui SM Lavstsen T Abdi AI Chmi-Sika Study Team
J Infect, (2024). 89:106252

The mRNA content of plasma extracellular vesicles provides a window into molecular processes in the brain during cerebral malaria.Kioko M Mwangi S Pance A Ochola-Oyier LI Kariuki S Newton C Bejon P Rayner JC Abdi AI
Sci Adv, (2024). 10:eadl2256

A retrospective analysis of P. falciparum drug resistance markers detects an early (2016/17) high prevalence of the k13 C469Y mutation in asymptomatic infections in Northern Uganda.Ogwang R Osoti V Wamae K Ndwiga L Muteru K Ningwa A Tuju J Kinyanjui S Osier F Marsh K Bejon P Idro R Ochola-Oyier LI
Antimicrob Agents Chemother, (2024). 68:e0157623

Profiling IgG and IgA antibody responses during vaccination and infection in a high-risk gonorrhoea population.Stejskal L Thistlethwaite A Ramirez-Bencomo F Rashmi S Harrison O Feavers IM Maiden MCJ Jerse A Barnes G Chirro O Chemweno J Nduati E Cehovin A Tang C Sanders EJ Derrick JP
Nat Commun, (2024). 15:6712

Utility of MALDI-TOF MS for determination of species identity and blood meal sources of primary malaria vectors on the Kenyan coast.Karisa J Ominde K Tuwei M Bartilol B Ondieki Z Musani H Wanjiku C Mwikali K Babu L Rono M Eminov M Mbogo C Bejon P Mwangangi J Laroche M Maia M
Wellcome Open Res, (2024). 8:151

Biomarkers of mortality in adults and adolescents with advanced HIV in sub-Saharan Africa.Riitho V Connon R Gwela A Namusanje J Nhema R Siika A Bwakura-Dangarembizi M Musiime V Berkley JA Szubert AJ Gibb DM Walker AS Klein N Prendergast AJ
Nat Commun, (2024). 15:5492

Evaluation of copromicroscopy, multiplex-qPCR and antibody serology for monitoring of human ascariasis in endemic settings.Mugo RM Rausch S Musimbi ZD Strube C Raulf MK Landt O Gichuki PM Ebner F Mwacharo J Odiere MR Ndungu FM Njomo DW Hartmann S
PLoS Negl Trop Dis, (2024). 18:e0012279

Barriers and enablers to the effective implementation of omics research in low- and middle-income countries.Nacis JS Kamande P Toni AT Mudibo E Musyimi R Popluechai S Dailey-Chwalibog T Voskuijl W Dable-Tupas G Shahid Asmsb Bascos NA Afroze F Chisti MJ Singa B Ngari M Tigoi C Mhango G Freitag H Potani I Mukisa J Kirolos A Mutasa K Ouedraogo LO Prentice AM Girma T Prendergast AJ Njunge J Kelly P Berkley JA Tickell KD Gonzales GB
Nat Biotechnol, (2024). 42:988-991

Tungiasis among children in Kenya is associated with poor nutrition status, absenteeism, poor school performance and high impact on quality of life.Elson L Kamau C Koech S Muthama C Gachomba G Sinoti E Chondo E Mburu E Wakio M Lore J Maia M Adetifa I Orindi B Bejon P Fillinger U
PLoS Negl Trop Dis, (2024). 18:e0011800

Reversible host cell surface remodelling limits immune recognition and maximizes transmission of Plasmodium falciparum gametocytes.Ngotho P Press KD Peedell M Muasya W Omondi BR Otoboh SE Seydel KB Kapulu M Laufer M Taylor T Bousema T Marti M
bioRxiv, (2024). :