Publications

Biosciences

Low-Dose Yellow Fever Vaccine in Adults in Africa.Kimathi D, Juan-Giner A, Bob NS, Orindi B, Namulwana ML, Diatta A, Cheruiyot S, Fall G, Dia M, Hamaluba MM, Nyehangane D, Karanja HK, Gitonga JN, Mugo D, Omuoyo DO, Hussein M, Oloo E, Kamau N, Wafula J, Bendera J, Silvester N, Mwavita J, Joshua M, Mwendwa J, Agababyona C, Ngetsa C, Aisha N, Moki F, Buluku T, Munene M, Mwanga-Amumpaire J, Lutwama J, Kayiwa J, Kamaara E, Barrett AD, Kaleebu P, Bejon P, Sall AA, Grais RF, Warimwe GM
N Engl J Med, (2025). 392:788-797

Beyond mosquitoes and malaria-ivermectin in Africa.Hammann F, Maia MF
Lancet Infect Dis, (2025). :

Elevating larval source management as a key strategy for controlling malaria and other vector-borne diseases in Africa.Okumu F, Moore SJ, Selvaraj P, Yafin AH, Juma EO, Shirima GG, Majambere S, Hardy A, Knols BGJ, Msugupakulya BJ, Finda M, Kahamba N, Thomsen E, Ahmed A, Zohdy S, Chaki P, DeChant P, Fornace K, Govella N, Gowelo S, Hakizimana E, Hamainza B, Ijumba JN, Jany W, Kafy HT, Kaindoa EW, Kariuki L, Kiware S, Kweka EJ, Lobo NF, Marrenjo D, Matoke-Muhia D, Mbogo C, McCann RS, Monroe A, Ndenga BA, Ngowo HS, Ochomo E, Opiyo M, Reithinger R, Sikaala CH, Tatarsky A, Takudzwa D, Trujillano F, Sherrard-Smith E
Parasit Vectors, (2025). 18:45

Detection of low frequency artemisinin resistance mutations, C469Y, P553L and A675V, and fixed antifolate resistance mutations in asymptomatic primary school children in Kenya.Osoti V, Wamae K, Ndwiga L, Gichuki PM, Okoyo C, Kepha S, Keitany K, Kandie R, Aricha S, Kiplagat R, Mwandawiro C, Bejon P, Snow RW, Ochola-Oyier LI
BMC Infect Dis, (2025). 25:73

Identification of novel PfEMP1 variants containing domain cassettes 11, 15 and 8 that mediate the Plasmodium falciparum virulence-associated rosetting phenotype.McLean FE, Omondi BR, Diallo N, Otoboh S, Kifude C, Abdi A, Lim R, Otto TD, Ghumra A, Rowe JA
PLoS Pathog, (2025). 21:e1012434

Regional action needed to halt antimalarial drug resistance in Africa.Martinez-Vega R, Ishengoma DS, Gosling R, Rosenthal PJ, Dondorp A, Barnes KI, Nsanzabana C, Djimde AA, Ochola-Oyier LI, Tibenderana J, Chimumbwa J, Golassa L, Kapologwe NA, Mbacham WF, Kamya MR, Fidock DA, Komatsu R, von Seidlein L, Dhorda M
Lancet, (2025). 405:7-10

Evaluation of population immunity against SARS-CoV-2 variants, EG.5.1, FY.4, BA.2.86, JN.1, JN.1.4, and KP.3.1.1 using samples from two health demographic surveillance systems in Kenya.Lugano D, Kutima B, Kimani M, Sigilai A, Gitonga J, Karani A, Akech D, Karia B, Ziraba AK, Maina A, Lambisia A, Omuoyo D, Mugo D, Lucinde R, Owuor S, Konyino G, Newman J, Bailey D, Nduati E, Githinji G, Agoti CN, Bejon P, Scott JAG, Agweyu A, Kagucia W, Warimwe GM, Sande C, Ochola-Oyier LI, Nyagwange J
BMC Infect Dis, (2024). 24:1474

Systemic biological mechanisms underpin poor post-discharge growth among severely wasted children with HIV.Mudibo EO, Bogaert J, Tigoi C, Ngari MM, Singa BO, Lancioni CL, Diallo AH, Mbale E, Mupere E, Mukisa J, Thitiri J, Timbwa M, Omer E, Ngao N, Musyimi R, Kahindi E, Bamouni RM, Bandsma RHJ, Kelly P, Prendergast AJ, McGrath CJ, Tickell KD, Walson JL, Berkley JA, Njunge JM, Gonzales GB
Nat Commun, (2024). 15:10299

Identification of complex Plasmodium falciparum genetic backgrounds circulating in Africa: a multicountry genomic epidemiology analysis.Miotto O, Amambua-Ngwa A, Amenga-Etego LN, Abdel Hamid MM, Adam I, Aninagyei E, Apinjoh T, Awandare GA, Bejon P, Bertin GI, Bouyou-Akotet M, Claessens A, Conway DJ, D'Alessandro U, Diakite M, Djimde A, Dondorp AM, Duffy P, Fairhurst RM, Fanello CI, Ghansah A, Ishengoma DS, Lawniczak M, Maiga-Ascofare O, Auburn S, Rosanas-Urgell A, Wasakul V, White NFD, Harrott A, Almagro-Garcia J, Pearson RD, Goncalves S, Ariani C, Bozdech Z, Hamilton WL, Simpson V, Kwiatkowski DP
Lancet Microbe, (2024). :100941

Prospective clinical surveillance for severe acute respiratory illness and COVID-19 vaccine effectiveness in Kenyan hospitals during the COVID-19 pandemic.Lucinde RK, Gathuri H, Isaaka L, Ogero M, Mumelo L, Kimego D, Mbevi G, Wanyama C, Otieno EO, Mwakio S, Saisi M, Isinde E, Oginga IN, Wachira A, Manuthu E, Kariuki H, Nyikuli J, Wekesa C, Otedo A, Bosire H, Okoth SB, Ongalo W, Mukabi D, Lusamba W, Muthui B, Adembesa I, Mithi C, Sood M, Ahmed N, Gituma B, Giabe M, Omondi C, Aman R, Amoth P, Kasera K, Were F, Nganga W, Berkley JA, Tsofa B, Mwangangi J, Bejon P, Barasa E, English M, Scott JAG, Akech S, Kagucia EW, Agweyu A, Etyang AO
BMC Infect Dis, (2024). 24:1246

ONT sequencing identifies a high prevalence of crt sensitive, triple mutant dhfr and single mutant dhps parasites within an ANC population in Nigeria.Adegbola AJ, Ndwiga L, Wamae K, Osoti V, Bolaji OO, Bejon P, Ochola-Oyier LI
Front Genet, (2024). 15:1470156

Molecular xenomonitoring reveals Anopheles funestus and An.�rivulorum as the primary vectors of lymphatic filariasis in coastal Kenya.Bartilol B, Babu L, Garama K, Karisa J, Kamau A, Mwandawiro C, Wanjiku C, Mbogo C, Maia M, Mwangangi J, Rono MK
Parasit Vectors, (2024). 17:425

Mosquitocidal efficacy and pharmacokinetics of single-dose ivermectin versus three-day dose regimen for malaria vector control in comparison with albendazole and no treatment: an open-label randomized controlled trial.Kamau Y, Tuwei M, Wanjiku C, Ominde K, Ngama M, Karisa J, Babu L, Muturi M, Mwatasa M, Adetifa J, Kern C, Duthaler U, Hammann F, Rabinovich R, Chaccour C, Maia MF
Int J Infect Dis, (2024). 148:107236

Mosquitocidal efficacy and pharmacokinetics of single-dose ivermectin versus three-day dose regimen for malaria vector control compared with albendazole and no treatment: An open-label randomized controlled trial.Kamau Y, Tuwei M, Wanjiku C, Ominde K, Ngama M, Karisa J, Babu L, Muturi M, Mwatasa M, Adetifa J, Kern C, Duthaler U, Hammann F, Rabinovich R, Chaccour C, Maia MF
Int J Infect Dis, (2024). 148:107236

Antibodies to PfEMP1 and Variant Surface Antigens: Protection after Controlled Human Malaria Infection in Semi-immune Kenyan Adults.Kinyua AW, Turner L, Kimingi HW, Mwai K, Mwikali K, Andisi C, Sim BKL, Bejon P, Kapulu MC, Kinyanjui SM, Lavstsen T, Abdi AI
J Infect, (2024). 89:106252

The mRNA content of plasma extracellular vesicles provides a window into molecular processes in the brain during cerebral malaria.Kioko M, Mwangi S, Pance A, Ochola-Oyier LI, Kariuki S, Newton C, Bejon P, Rayner JC, Abdi AI
Sci Adv, (2024). 10:eadl2256

A retrospective analysis of P. falciparum drug resistance markers detects an early (2016/17) high prevalence of the k13 C469Y mutation in asymptomatic infections in Northern Uganda.Ogwang R, Osoti V, Wamae K, Ndwiga L, Muteru K, Ningwa A, Tuju J, Kinyanjui S, Osier F, Marsh K, Bejon P, Idro R, Ochola-Oyier LI
Antimicrob Agents Chemother, (2024). 68:e0157623

Lactoferrin and lysozyme to promote nutritional, clinical and enteric recovery: a protocol for a factorial, blinded, placebo-controlled randomised trial among children with diarrhoea and malnutrition (the Boresha Afya trial).Tiwari R, Tickell KD, Yoshioka E, Otieno J, Shah A, Richardson BA, Keter L, Okello M, Nyabinda C, Trehan I, McGrath CJ, Means AR, Houpt ER, Liu J, Platts-Mills JA, Njunge JM, Rwigi D, Diakhate MM, Nyaoke J, Ochola E, John-Stewart G, Walson JL, Pavlinac PB, Singa BO
BMJ Open, (2024). 14:e079448

Profiling IgG and IgA antibody responses during vaccination and infection in a high-risk gonorrhoea population.Stejskal L, Thistlethwaite A, Ramirez-Bencomo F, Rashmi S, Harrison O, Feavers IM, Maiden MCJ, Jerse A, Barnes G, Chirro O, Chemweno J, Nduati E, Cehovin A, Tang C, Sanders EJ, Derrick JP
Nat Commun, (2024). 15:6712

Linking Cerebral Malaria Pathogenesis to APOE-Mediated Amyloidosis: Observations and Hypothesis.Kioko M, Mwangi S, Njunge JM, Berkley JA, Bejon P, Abdi AI
Mol Neurobiol, (2024). :Online ahead of print