Recent publications

Parasite antigens on the infected red cell surface are targets for naturally acquired immunity to malaria.Bull, P. C. Lowe, B. S. Kortok, M. Molyneux, C. S. Newbold, C. I. Marsh, K.
Nat Med, (1998). 4:358-60

Chlorproguanil/dapsone for uncomplicated Plasmodium falciparum malaria in young children: pharmacokinetics and therapeutic range.Winstanley, P. Watkins, W. Muhia, D. Szwandt, S. Amukoye, E. Marsh, K.
Trans R Soc Trop Med Hyg, (1997). 91:322-7

Poor efficacy of antimalarial biguanide-dapsone combinations in the treatment of acute, uncomplicated, falciparum malaria in Thailand.Wilairatana, P. Kyle, D. E. Looareesuwan, S. Chinwongprom, K. Amradee, S. White, N. J. Watkins, W. M.
Ann Trop Med Parasitol, (1997). 91:125-32

The efficacy of antifolate antimalarial combinations in Africa: a predictive model based on pharmacodynamic and pharmacokinetic analyses.Watkins, W. M. Mberu, E. K. Winstanley, P. A. Plowe, C. V.
Parasitol Today, (1997). 13:459-64

Resistance to antifolates in Plasmodium falciparum monitored by sequence analysis of dihydropteroate synthetase and dihydrofolate reductase alleles in a large number of field samples of diverse origins.Wang, P. Lee, C. S. Bayoumi, R. Djimde, A. Doumbo, O. Swedberg, G. Dao, L. D. Mshinda, H. Tanner, M. Watkins, W. M. Sims, P. F. Hyde, J. E.
Mol Biochem Parasitol, (1997). 89:161-77

Resistance to pyrimethamine/sulfadoxine in Plasmodium falciparum in 12 villages in north east Tanzania and a test of chlorproguanil/dapsone.Trigg, J. K. Mbwana, H. Chambo, O. Hills, E. Watkins, W. Curtis, C. F.
Acta Trop, (1997). 63:185-9

Relation between severe malaria morbidity in children and level of Plasmodium falciparum transmission in Africa.Snow, R. W. Omumbo, J. A. Lowe, B. Molyneux, C. S. Obiero, J. O. Palmer, A. Weber, M. W. Pinder, M. Nahlen, B. Obonyo, C. Newbold, C. Gupta, S. Marsh, K.
Lancet, (1997). 349:1650-4

The effects of malaria control on nutritional status in infancy.Snow, R. W. Molyneux, C. S. Njeru, E. K. Omumbo, J. Nevill, C. G. Muniu, E. Marsh, K.
Acta Trop, (1997). 65:1-10

Epidemiological features of severe paediatric malaria in north western Ethiopia.Seboxa, T. Snow, R. W.
East Afr Med J, (1997). 74:780-3

Inflammatory mediators in children with protein-energy malnutrition.Sauerwein, R. W. Mulder, J. A. Mulder, L. Lowe, B. Peshu, N. Demacker, P. N. van der Meer, J. W. Marsh, K.
Am J Clin Nutr, (1997). 65:1534-9

Autopsy findings in HIV-1-infected adults in Kenya.Rana, F. Hawken, M. P. Meme, H. K. Chakaya, J. M. Githui, W. A. Odhiambo, J. A. Porter, J. D. McAdam, K. P. Lucas, S. J.
J Acquir Immune Defic Syndr Hum Retrovirol, (1997). 14:83-5

Mutations in Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase and epidemiologic patterns of pyrimethamine-sulfadoxine use and resistance.Plowe, C. V. Cortese, J. F. Djimde, A. Nwanyanwu, O. C. Watkins, W. M. Winstanley, P. A. Estrada-Franco, J. G. Mollinedo, R. E. Avila, J. C. Cespedes, J. L. Carter, D. Doumbo, O. K.
J Infect Dis, (1997). 176:1590-6

Bronchial hyperresponsiveness: what causes twitchy airways?.Page, C.
J Pharm Pharmacol, (1997). 49 Suppl 3:9-11

Severe anaemia in children living in a malaria endemic area of Kenya.Newton, C. R. Warn, P. A. Winstanley, P. A. Peshu, N. Snow, R. W. Pasvol, G. Marsh, K.
Trop Med Int Health, (1997). 2:165-78

Intracranial hypertension in Africans with cerebral malaria.Newton, C. R. Crawley, J. Sowumni, A. Waruiru, C. Mwangi, I. English, M. Murphy, S. Winstanley, P. A. Marsh, K. Kirkham, F. J.
Arch Dis Child, (1997). 76:219-26

Coma scales for children with severe falciparum malaria.Newton, C. R. Chokwe, T. Schellenberg, J. A. Winstanley, P. A. Forster, D. Peshu, N. Kirkham, F. J. Marsh, K.
Trans R Soc Trop Med Hyg, (1997). 91:161-5

PfEMP1, polymorphism and pathogenesis.Newbold, C. I. Craig, A. G. Kyes, S. Berendt, A. R. Snow, R. W. Peshu, N. Marsh, K.
Ann Trop Med Parasitol, (1997). 91:551-7

Receptor-specific adhesion and clinical disease in Plasmodium falciparum.Newbold, C. Warn, P. Black, G. Berendt, A. Craig, A. Snow, B. Msobo, M. Peshu, N. Marsh, K.
Am J Trop Med Hyg, (1997). 57:389-98

The disposition of intramuscular artemether in children with cerebral malaria; a preliminary study.Murphy, S. A. Mberu, E. Muhia, D. English, M. Crawley, J. Waruiru, C. Lowe, B. Newton, C. R. Winstanley, P. Marsh, K. Watkins, W. M.
Trans R Soc Trop Med Hyg, (1997). 91:331-4

Host-parasite interaction and morbidity in malaria endemic areas.Marsh, K. Snow, R. W.
Philos Trans R Soc Lond B Biol Sci, (1997). 352:1385-94