0709 203000 - Nairobi 0709 983000 - Kilifi
0709 203000 - NRB 0709 983000 - Kilifi
0709 203000 - NRB | 0709 983000 - Kilifi

Bio


Isabella Oyier is the Head of the Biosciences Department at KEMRI-Wellcome Trust Research Program (KWTRP), a Professor of Molecular Epidemiology, Nuffield Department of Medicine, University of Oxford a Calestous Juma Fellow, funded by BMGF and a Global Research Fellow at Reuben College, University of Oxford. Her current research focuses on integrating malaria molecular epidemiology into routine surveillance in Kenya. A project that partners with the Division of National Malaria Programme to implement malaria molecular surveillance activities. During the COVID-19 pandemic, she led the COVID-19 testing for the Coastal region. KWTRP was a regional COVID-19 genomic surveillance reference lab for Africa CDC and WHO-Afro and she led and coordinated this effort. In addition, she is coordinating the scale up COVID-19 immunological surveillance in the East Africa region, to determine genetic variants with immune escape potential. More recently she is co-leading a Wellcome funded 4 pathogen genomics surveillance grant that cuts across 8 countries, Cambodia, Indonesia, Kenya, Laos, Malawi, South Africa, Thailand and Vietnam.

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Current Work


Her research interests are in Plasmodium falciparum malaria molecular epidemiology, focusing on the spatial and temporal use of molecular tools to: 1) examine genetic variation in merozoite antigens that are potential candidates for blood stage vaccines and its impact on naturally acquired immunity; 2) define complexity of infection while examining the impact of interventions or changes in malaria epidemiology; 3) distinguish persistent infections and reinfections in both therapeutic efficacy studies and in longitudinal follow up of asymptomatic individuals; and 4) monitor drug resistance molecular markers.

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Recent publications


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