Sophie Uyoga

Improving the diagnosis of severe malaria in African children using platelet counts and plasma PfHRP2 concentrations.Watson JA Uyoga S Wanjiku P Makale J Nyutu GM Mturi N George EC Woodrow CJ Day NPJ Bejon P Opoka RO Dondorp AM John CC Maitland K Williams TN White NJ
Sci Transl Med, (2022). 14:eabn5040

Sickle cell anaemia and severe Plasmodium falciparum malaria: a secondary analysis of the Transfusion and Treatment of African Children Trial (TRACT).Uyoga S Olupot-Olupot P Connon R Kiguli S Opoka RO Alaroker F Muhindo R Macharia AW Dondorp AM Gibb DM Walker AS George EC Maitland K Williams TN
Lancet Child Adolesc Health, (2022). 6:606-613

The impact of malaria-protective red blood cell polymorphisms on parasite biomass in children with severe Plasmodium falciparum malaria.Uyoga S Watson JA Wanjiku P Rop JC Makale J Macharia AW Kariuki SN Nyutu GM Shebe M Mosobo M Mturi N Rockett KA Woodrow CJ Dondorp AM Maitland K White NJ Williams TN
Nat Commun, (2022). 13:3307

A Clinical and Physiological Prospective Observational Study on the Management of Pediatric Shock in the Post-Fluid Expansion as Supportive Therapy Trial Era.Obonyo NG Olupot-Olupot P Mpoya A Nteziyaremye J Chebet M Uyoga S Muhindo R Fanning JP Shiino K Chan J Fraser JF Maitland K
Pediatr Crit Care Med, (2022). 23:502-513

Whole blood versus red cell concentrates for children with severe anaemia: a secondary analysis of the Transfusion and Treatment of African Children (TRACT) trial.George EC Uyoga S M'Baya B Kyeyune Byabazair D Kiguli S Olupot-Olupot P Opoka RO Chagaluka G Alaroker F Williams TN Bates I Mbanya D Gibb DM Walker AS Maitland K Tract trial study group
Lancet Glob Health, (2022). 10:e360-e368

A predictive algorithm for identifying children with sickle cell anemia among children admitted to hospital with severe anemia in Africa.Olupot-Olupot P Connon R Kiguli S Opoka RO Alaroker F Uyoga S Nakuya M Okiror W Nteziyaremye J Ssenyondo T Nabawanuka E Kayaga J Williams Mukisa C Amorut D Muhindo R Frost G Walsh K Macharia AW Gibb DM Walker AS George EC Maitland K Williams TN
Am J Hematol, (2022). 97:527-536

Comparative performance of WANTAI ELISA for total immunoglobulin to receptor binding protein and an ELISA for IgG to spike protein in detecting SARS-CoV-2 antibodies in Kenyan populations.Nyagwange J Kutima B Mwai K Karanja HK Gitonga JN Mugo D Uyoga S Tuju J Ochola-Oyier LI Ndungu F Bejon P Agweyu A Adetifa IMO Scott JAG Warimwe GM
J Clin Virol, (2022). 146:105061

Seroprevalence of Antibodies to Severe Acute Respiratory Syndrome Coronavirus 2 Among Healthcare Workers in Kenya.Etyang AO Lucinde R Karanja H Kalu C Mugo D Nyagwange J Gitonga J Tuju J Wanjiku P Karani A Mutua S Maroko H Nzomo E Maitha E Kamuri E Kaugiria T Weru J Ochola LB Kilimo N Charo S Emukule N Moracha W Mukabi D Okuku R Ogutu M Angujo B Otiende M Bottomley C Otieno E Ndwiga L Nyaguara A Voller S Agoti CN Nokes DJ Ochola-Oyier LI Aman R Amoth P Mwangangi M Kasera K Ng'ang'a W Adetifa IMO Wangeci Kagucia E Gallagher K Uyoga S Tsofa B Barasa E Bejon P Scott JAG Agweyu A Warimwe GM
Clin Infect Dis, (2022). 74:288-293

Quantifying previous SARS-CoV-2 infection through mixture modelling of antibody levels.Bottomley C Otiende M Uyoga S Gallagher K Kagucia EW Etyang AO Mugo D Gitonga J Karanja H Nyagwange J Adetifa IMO Agweyu A Nokes DJ Warimwe GM Scott JAG
Nat Commun, (2021). 12:6196

Anti-Severe Acute Respiratory Syndrome Coronavirus 2 Immunoglobulin G Antibody Seroprevalence Among Truck Drivers and Assistants in Kenya.Kagucia EW Gitonga JN Kalu C Ochomo E Ochieng B Kuya N Karani A Nyagwange J Karia B Mugo D Karanja HK Tuju J Mutiso A Maroko H Okubi L Maitha E Ajuck H Mukabi D Moracha W Bulimu D Andanje N Aman R Mwangangi M Amoth P Kasera K Ng'ang'a W Nyaguara A Voller S Otiende M Bottomley C Agoti CN Ochola-Oyier LI Adetifa IMO Etyang AO Gallagher KE Uyoga S Barasa E Bejon P Tsofa B Agweyu A Warimwe GM Scott JAG Magarini Sub-County Tda Sars-CoV-2 Serosurveillance Team The Busia County TDASars-CoV-Serosurveillance Team
Open Forum Infect Dis, (2021). 8:ofab314

COVID-19 transmission dynamics underlying epidemic waves in Kenya.Brand SPC Ojal J Aziza R Were V Okiro EA Kombe IK Mburu C Ogero M Agweyu A Warimwe GM Nyagwange J Karanja H Gitonga JN Mugo D Uyoga S Adetifa IMO Scott JAG Otieno E Murunga N Otiende M Ochola-Oyier LI Agoti CN Githinji G Kasera K Amoth P Mwangangi M Aman R Ng'ang'a W Tsofa B Bejon P Keeling MJ Nokes DJ Barasa E
Science, (2021). 374:989-994

Prevalence of SARS-CoV-2 Antibodies From a National Serosurveillance of Kenyan Blood Donors, January-March 2021.Uyoga S Adetifa IMO Otiende M Yegon C Agweyu A Warimwe GM Scott JAG
JAMA, (2021). 326:1436-1438

Incidence and predictors of hospital readmission in children presenting with severe anaemia in Uganda and Malawi: a secondary analysis of TRACT trial data.Connon R George EC Olupot-Olupot P Kiguli S Chagaluka G Alaroker F Opoka RO Mpoya A Walsh K Engoru C Nteziyaremye J Mallewa M Kennedy N Nakuya M Namayanja C Nabawanuka E Sennyondo T Amorut D Williams Musika C Bates I Boele van Hensbroek M Evans JA Uyoga S Williams TN Frost G Gibb DM Maitland K Walker AS Tract trial group
BMC Public Health, (2021). 21:1480

Improving statistical power in severe malaria genetic association studies by augmenting phenotypic precision.Watson JA Ndila CM Uyoga S Macharia A Nyutu G Mohammed S Ngetsa C Mturi N Peshu N Tsofa B Rockett K Leopold S Kingston H George EC Maitland K Day NP Dondorp AM Bejon P Williams TN Holmes CC White NJ
Elife, (2021). 10:

Temporal trends of SARS-CoV-2 seroprevalence during the first wave of the COVID-19 epidemic in Kenya.Adetifa IMO Uyoga S Gitonga JN Mugo D Otiende M Nyagwange J Karanja HK Tuju J Wanjiku P Aman R Mwangangi M Amoth P Kasera K Ng'ang'a W Rombo C Yegon C Kithi K Odhiambo E Rotich T Orgut I Kihara S Bottomley C Kagucia EW Gallagher KE Etyang A Voller S Lambe T Wright D Barasa E Tsofa B Bejon P Ochola-Oyier LI Agweyu A Scott JAG Warimwe GM
Nat Commun, (2021). 12:3966

Point-of-care haemoglobin testing in African hospitals: a neglected essential diagnostic test.Uyoga S George EC Bates I Olupot-Olupot P Chimalizeni Y Molyneux EM Maitland K
Br J Haematol, (2021). 193:894-901

Transfusion management of severe anaemia in African children: a consensus algorithm.Maitland K Kiguli S Olupot-Olupot P Opoka RO Chimalizeni Y Alaroker F Uyoga S Kyeyune-Byabazaire D M'Baya B Bates I Williams TN Munube D Mbanya D Molyneux EM South A Walker AS Gibb DM George EC Tract Stakeholders meeting group
Br J Haematol, (2021). 193:1247-1259

Seroprevalence of anti-SARS-CoV-2 IgG antibodies in Kenyan blood donors.Uyoga S Adetifa IMO Karanja HK Nyagwange J Tuju J Wanjiku P Aman R Mwangangi M Amoth P Kasera K Ng'ang'a W Rombo C Yegon C Kithi K Odhiambo E Rotich T Orgut I Kihara S Otiende M Bottomley C Mupe ZN Kagucia EW Gallagher KE Etyang A Voller S Gitonga JN Mugo D Agoti CN Otieno E Ndwiga L Lambe T Wright D Barasa E Tsofa B Bejon P Ochola-Oyier LI Agweyu A Scott JAG Warimwe GM
Science, (2021). 371:79-82

Plasma Plasmodium falciparum Histidine-rich Protein 2 Concentrations in Children With Malaria Infections of Differing Severity in Kilifi, Kenya.Uyoga S Wanjiku P Rop JC Makale J Macharia AW Nyutu GM Shebe M Awuondo KA Mturi N Woodrow CJ Dondorp AM Maitland K Williams TN
Clin Infect Dis, (2021). 73:e2415-e2423

Serosurveillance for SARS-CoV-2 Antibodies in a cohort of Health Care Workers in Kenya..Etyang AO Lucinde R Gitonga JN Kalu C Karani A Nyagwange J Mugo D Karanja HK Tuju J Mutiso A Maroko H Okubi L Maitha E Mukabi D The HCW SARS-CoV-2 Serosurveillance Team, Aman R Mwangangi M Amoth P Kasera K NgÔÇÖangÔÇÖa W Nyaguara A Voller S Otiende M Bottomley C Agoti CN Ochola-Oyier LI Adetifa IMO Gallagher KE Uyoga S Barasa E Bejon P Tsofa B Agweyu A Warimwe GM Scott JAG
1st International Conference on Public Health in Africa (CPHIA), (2021). :