0709 203000 - Nairobi 0709 983000 - Kilifi
0709 203000 - NRB 0709 983000 - Kilifi
0709 203000 - NRB | 0709 983000 - Kilifi

Abstract

Temporal trends of SARS-CoV-2 seroprevalence during the first wave of the COVID-19 epidemic in Kenya

Adetifa IMO Uyoga S Gitonga JN Mugo D Otiende M Nyagwange J Karanja HK Tuju J Wanjiku P Aman R Mwangangi M Amoth P Kasera K Ng'ang'a W Rombo C Yegon C Kithi K Odhiambo E Rotich T Orgut I Kihara S Bottomley C Kagucia EW Gallagher KE Etyang A Voller S Lambe T Wright D Barasa E Tsofa B Bejon P Ochola-Oyier LI Agweyu A Scott JAG Warimwe GM
Nat Commun. 2021;123966

Permenent descriptor
https://doi.org/10.1038/s41467-021-24062-3


Observed SARS-CoV-2 infections and deaths are low in tropical Africa raising questions about the extent of transmission. We measured SARS-CoV-2 IgG by ELISA in 9,922 blood donors across Kenya and adjusted for sampling bias and test performance. By 1st September 2020, 577 COVID-19 deaths were observed nationwide and seroprevalence was 9.1% (95%CI 7.6-10.8%). Seroprevalence in Nairobi was 22.7% (18.0-27.7%). Although most people remained susceptible, SARS-CoV-2 had spread widely in Kenya with apparently low associated mortality.