Wellcome Open Res

Safety and immunogenicity of ChAdOx1 nCoV-19 (AZD1222) vaccine in adults in Kenya: a phase 1/2 single-blind, randomised controlled trial.Hamaluba, M. Sang, S. Orindi, B. Njau, I. Karanja, H. Kamau, N. Gitonga, J. N. Mugo, D. Wright, D. Nyagwange, J. Kutima, B. Omuoyo, D. Mwatasa, M. Ngetsa, C. Agoti, C. Cheruiyot, S. Nyaguara, A. Munene, M. Mturi, N. Oloo, E. Ochola-Oyier, L. Mumba, N. Mauncho, C. Namayi, R. Davies, A. Tsofa, B. Nduati, E. W. Aliyan, N. Kasera, K. Etyang, A. Boyd, A. Hill, A. Gilbert, S. Douglas, A. Pollard, A. Bejon, P. Lambe, T. Warimwe, G. C. O. V. Vaccine Trial Group
Wellcome Open Res, (2023). 8:182

Mortality among non-severely under nourished children with pneumonia globally: protocol for a systematic review and meta-analysis.Nalwanga, D. Bakker, C. Kiggwe, A. Negash, A. A. Ocan, M. Briend, A. Maitland, K. Musiiime, V. Karamagi, C.
Wellcome Open Res, (2023). 8:551

Ethical issues of involving people with intellectual disabilities in genomic research: a scoping review protocol.Chepkirui, D. Kipkemoi, P. Bitta, M. Harris, E. Musesengwa, R. Kamuya, D.
Wellcome Open Res, (2023). 8:340

Universal iron supplementation: the best strategy to tackle childhood anaemia in malaria-endemic countries?.Karthikappallil, R. Atkinson, S. H.
Wellcome Open Res, (2023). 8:345

A rapid review of community engagement and informed consent processes for adaptive platform trials and alternative design trials for public health emergencies.Davies, A. Ormel, I. Bernier, A. Harriss, E. Mumba, N. Gobat, N. Schwartz, L. Cheah, P. Y.
Wellcome Open Res, (2023). 8:194

Severe anaemia, iron deficiency, and susceptibility to invasive bacterial infections.Abuga, K. M. Nairz, M. MacLennan, C. A. Atkinson, S. H.
Wellcome Open Res, (2023). 8:48

Assessment of gestational age at antenatal care visits among Kenyan women to inform delivery of a maternal respiratory syncytial virus (RSV) vaccine in low- and middle-income countries.Nyiro, J. U. Nyawanda, B. O. Bukusi, E. Mureithi, M. W. Murunga, N. Nokes, D. J. Bigogo, G. Otieno, N. A. Opere, V. A. Ouma, A. Pecenka, C. Munywoki, P. K.
Wellcome Open Res, (2023). 8:154

Pf7: an open dataset of Plasmodium falciparum genome variation in 20,000 worldwide samples.MalariaGen, Abdel Hamid, M. M. Abdelraheem, M. H. Acheampong, D. O. Ahouidi, A. Ali, M. Almagro-Garcia, J. Amambua-Ngwa, A. Amaratunga, C. Amenga-Etego, L. Andagalu, B. Anderson, T. Andrianaranjaka, V. Aniebo, I. Aninagyei, E. Ansah, F. Ansah, P. O. Apinjoh, T. Arnaldo, P. Ashley, E. Auburn, S. Awandare, G. A. Ba, H. Baraka, V. Barry, A. Bejon, P. Bertin, G. I. Boni, M. F. Borrmann, S. Bousema, T. Bouyou-Akotet, M. Branch, O. Bull, P. C. Cheah, H. Chindavongsa, K. Chookajorn, T. Chotivanich, K. Claessens, A. Conway, D. J. Corredor, V. Courtier, E. Craig, A. D'Alessandro, U. Dama, S. Day, N. Denis, B. Dhorda, M. Diakite, M. Djimde, A. Dolecek, C. Dondorp, A. Doumbia, S. Drakeley, C. Drury, E. Duffy, P. Echeverry, D. F. Egwang, T. G. Enosse, S. M. M. Erko, B. Fairhurst, R. M. Faiz, A. Fanello, C. A. Fleharty, M. Forbes, M. Fukuda, M. Gamboa, D. Ghansah, A. Golassa, L. Goncalves, S. Harrison, G. L. A. Healy, S. A. Hendry, J. A. Hernandez-Koutoucheva, A. Hien, T. T. Hill, C. A. Hombhanje, F. Hott, A. Htut, Y. Hussein, M. Imwong, M. Ishengoma, D. Jackson, S. A. Jacob, C. G. Jeans, J. Johnson, K. J. Kamaliddin, C. Kamau, E. Keatley, J. Kochakarn, T. Konate, D. S. Konate, A. Kone, A. Kwiatkowski, D. P. Kyaw, M. P. Kyle, D. Lawniczak, M. Lee, S. K. Lemnge, M. Lim, P. Lon, C. Loua, K. M. Mandara, C. I. Marfurt, J. Marsh, K. Maude, R. J. Mayxay, M. Maiga-Ascofare, O. Miotto, O. Mita, T. Mobegi, V. Mohamed, A. O. Mokuolu, O. A. Montgomery, J. Morang'a, C. M. Mueller, I. Murie, K. Newton, P. N. Ngo Duc, T. Nguyen, T. Nguyen, T. N. Nguyen Thi Kim, T. Nguyen Van, H. Noedl, H. Nosten, F. Noviyanti, R. Ntui, V. N. Nzila, A. Ochola-Oyier, L. I. Ocholla, H. Oduro, A. Omedo, I. Onyamboko, M. A. Ouedraogo, J. B. Oyebola, K. Oyibo, W. A. Pearson, R. Peshu, N. Phyo, A. P. Plowe, C. V. Price, R. N. Pukrittayakamee, S. Quang, H. H. Randrianarivelojosia, M. Rayner, J. C. Ringwald, P. Rosanas-Urgell, A. Rovira-Vallbona, E. Ruano-Rubio, V. Ruiz, L. Saunders, D. Shayo, A. Siba, P. Simpson, V. J. Sissoko, M. S. Smith, C. Su, X. Z. Sutherland, C. Takala-Harrison, S. Talman, A. Tavul, L. Thanh, N. V. Thathy, V. Thu, A. M. Toure, M. Tshefu, A. Verra, F. Vinetz, J. Wellems, T. E. Wendler, J. White, N. J. Whitton, G. Yavo, W. van der Pluijm, R. W.
Wellcome Open Res, (2023). 8:22

A pragmatic randomized controlled trial of standard care versus corticosteroids plus standard care for treatment of pneumonia in adults admitted to Kenyan hospitals (SONIA).Lucinde, R. Abdi, A. Orindi, B. Mwakio, S. Gathuri, H. Onyango, E. Chira, S. Ogero, M. Isaaka, L. Shangala, J. Oginga, I. N. Wachira, A. Manuthu, E. Kariuki, H. Nyikuli, J. Wekesa, C. Otedo, A. Bosire, H. Okoth, S. B. Ongalo, W. Mukabi, D. Lusamba, W. Muthui, B. Kirui, N. Adembesa, I. Mithi, C. Sood, M. Ahmed, N. Gituma, B. Ongaki, V. B. Giabe, M. Omondi, C. Ombajo, L. A. Kagucia, W. English, M. Hamaluba, M. Ochola-Oyier, L. I. Kamuya, D. Bejon, P. Agweyu, A. Akech, S. Etyang, A. O.
Wellcome Open Res, (2022). 7:269

Examining the impact of implementing routine rotavirus vaccination on the number of paediatric admissions due to diarrhoea and dehydration in Kenyan hospitals: A study using interrupted time series analysis.Chelangat, D. Malla, L. Langat, R. C. Akech, S. Clinical Information Network Author, Group
Wellcome Open Res, (2022). 7:2

A cross-sectional analysis identifies a low prevalence of Plasmodium ovale species infections in symptomatic and asymptomatic individuals in Kilifi county, Kenya.Akinyi, M. Y. Chifwete, M. Ndwiga, L. Kimenyi, K. M. Osoti, V. Ochola-Oyier, L. I.
Wellcome Open Res, (2022). 7:207

The CINAMR (Clinical Information Network-Antimicrobial Resistance) Project: A pilot microbial surveillance using hospitals linked to regional laboratories in Kenya: Study Protocol.Akech, S. Nyamwaya, B. Gachoki, J. Ogero, M. Kigo, J. Maina, M. Mutua, E. Ooko, E. Bejon, P. Mwarumba, S. Bahati, F. Mvera, B. Musyimi, R. Onsare, R. Hutter, J. Tanui, E. Wesangula, E. Turner, P. Dunachie, S. Lucey, O. McKnight, J. Cinamr Investigators
Wellcome Open Res, (2022). 7:256

A network of empirical ethics teams embedded in research programmes across multiple sites: opportunities and challenges in contributing to COVID-19 research and responses.Ngwenya, N. Ilo Van Nuil, J. Nyirenda, D. Chambers, M. Cheah, P. Y. Seeley, J. Chi, P. Mafuleka, L. Nkosi, B. Kamuya, D. Davies, A. Schneiders, M. L. Mumba, N. Dlamini, S. Desmond, N. Marsh, V. Rippon, D. Parker, M. Molyneux, S.
Wellcome Open Res, (2022). 7:48

Targeted amplicon deep sequencing of ama1 and mdr1 to track within-host P. falciparum diversity throughout treatment in a clinical drug trial.Wamae, K. Ndwiga, L. Kharabora, O. Kimenyi, K. Osoti, V. de Laurent, Z. Wambua, J. Musyoki, J. Ngetsa, C. Kalume, P. Mwambingu, G. Hamaluba, M. van der Pluijm, R. Dondorp, A. M. Bailey, J. Juliano, J. Bejon, P. Ochola-Oyier, L.
Wellcome Open Res, (2022). 7:95

Strategies for improving mental health and wellbeing used by adults ageing with HIV from the Kenyan coast: a qualitative exploration.Mwangala, P. N. Wagner, R. G. Newton, C. R. Abubakar, A.
Wellcome Open Res, (2022). 7:221

Addressing the need for an appropriate skilled delivery care workforce in Burundi to support Maternal and Newborn Health Service Delivery Redesign (MNH-Redesign): a sequential study protocol.Habonimana, D. Leckcivilize, A. Nicodemo, C. English, M.
Wellcome Open Res, (2022). 7:196

Revealing the extent of the first wave of the COVID-19 pandemic in Kenya based on serological and PCR-test data.Ojal, J. Brand, S. P. C. Were, V. Okiro, E. A. Kombe, I. K. Mburu, C. Aziza, R. Ogero, M. Agweyu, A. Warimwe, G. M. Uyoga, S. Adetifa, I. M. O. Scott, J. A. G. Otieno, E. Ochola-Oyier, L. I. Agoti, C. N. Kasera, K. Amoth, P. Mwangangi, M. Aman, R. Ng'ang'a, W. Tsofa, B. Bejon, P. Barasa, E. Keeling, M. J. Nokes, D. J.
Wellcome Open Res, (2022). 6:127

Detection of pathogens associated with early-onset neonatal sepsis in cord blood at birth using quantitative PCR.Obiero, C. W. Gumbi, W. Mwakio, S. Mwangudzah, H. Seale, A. C. Taniuchi, M. Liu, J. Houpt, E. Berkley, J. A.
Wellcome Open Res, (2022). 7:3

Epidemiology of COVID-19 infections on routine polymerase chain reaction (PCR) and serology testing in Coastal Kenya.Nyagwange, J. Ndwiga, L. Muteru, K. Wamae, K. Tuju, J. Testing Team, C. Kutima, B. Gitonga, J. Karanja, H. Mugo, D. Kasera, K. Amoth, P. Murunga, N. Babu, L. Otieno, E. Githinji, G. Nokes, D. J. Tsofa, B. Orindi, B. Barasa, E. Warimwe, G. Agoti, C. N. Bejon, P. Ochola-Oyier, L. I.
Wellcome Open Res, (2022). 7:69

Missed nursing care in acute care hospital settings in low-middle income countries: a systematic review protocol.Imam, A. Obiesie, S. Aluvaala, J. Maina, M. Gathara, D. English, M.
Wellcome Open Res, (2022). 6:359