Francis Ndungu

Pre-COVID-19 ex vivo cross-reactive IFN-gamma cellular response to SARS-CoV-2 spike overlapping peptides is more prevalent among Kenyan compared to Swedish adults.Wanjiku P Orindi B Mwacharo J Chemweno J Karanja HK Kronsteiner B Kai O Wright D Ochola-Oyier LI Sundling C Dunachie S Warimwe GM Farnert A Bejon P Ndungu FM Nduati EW
BMC Infect Dis, (2026). 26:174

Induction of an early IFN-gamma cellular response and high plasma levels of SDF-1alpha are inversely associated with COVID-19 severity and residence in rural areas in Kenyan patients.Wanjiku P Orindi B Kimotho J Sayed S Shah R Saleh M Mwacharo J Maronga C Olouch V Karanu A Shah J Nneka Z Ochola-Oyier LI Abdi AI Dunachie S Bejon P Nduati EW Ndungu FM
PLoS One, (2025). 20:e0316967

OSBPL11 is an African-specific locus associated with 25-hydroxyvitamin D concentrations and cardiometabolic health.Mogire RM Muriuki JM Bayimenye RF Mentzer AJ Chong A Gouveia MH Bentley AR Band G King'ori P Mitchell R Webb EL Sengupta D Ekunwe L Ndungu FM Morovat A Macharia AW Cutland CL Hemani G Sirima SB Ramsay M Figueiredo CA Prentice AM Madhi SA Raffield LM Sandhu MS Bejon P Smith GD Elliott AM Williams TN Rotimi C Bourne CR Burgett A Adeyemo A Atkinson SH
medRxiv, (2025). :

Development of an oral regimen of unithiol for the treatment of snakebite envenoming: a phase 1 open-label dose-escalation safety trial and pharmacokinetic analysis in healthy Kenyan adults.Abouyannis M Nyambura YK Ngome S Riako D Musyoki J Muiruri C Orindi B Else L Amara A Dickinson L Clare RH Albulescu LO Westhorpe AP Kool J Adetifa I Ndungu FM FitzGerald R Khoo S Lalloo DG Casewell NR Hamaluba M
EBioMedicine, (2025). 113:105600

Kinetics of naturally induced binding and neutralising anti-SARS-CoV-2 antibody levels and potencies among SARS-CoV-2 infected Kenyans with diverse grades of COVID-19 severity: an observational study.Kimotho J Sein Y Sayed S Shah R Mwai K Saleh M Wanjiku P Mwacharo J Nyagwange J Karanja H Kutima B Gitonga JN Mugo D Karanu A Moranga L Oluoch V Shah J Mutiso J Mburu A Nneka Z Betti P Usyu Mutinda W Abdi AI Bejon P Ochola-Oyier LI Warimwe GM Nduati EW Ndungu FM
Wellcome Open Res, (2025). 8:350

Evaluation of copromicroscopy, multiplex-qPCR and antibody serology for monitoring of human ascariasis in endemic settings.Mugo RM Rausch S Musimbi ZD Strube C Raulf MK Landt O Gichuki PM Ebner F Mwacharo J Odiere MR Ndungu FM Njomo DW Hartmann S
PLoS Negl Trop Dis, (2024). 18:e0012279

Correlations between three ELISA protocols measurements of RTS,S/AS01-induced anti-CSP IgG antibodies.Mugo RM Orindi B Shee FM Bellamy D Mwacharo J Ewer KJ Bejon P Ndungu FM
PLoS One, (2023). 18:e0286117

Transcriptomic signatures induced by the Ebola virus vaccine rVSVDeltaG-ZEBOV-GP in adult cohorts in Europe, Africa, and North America: a molecular biomarker study.Vianello E Gonzalez-Dias P van Veen S Engele CG Quinten E Monath TP Medaglini D Vsv-Ebovac Consortium Vsv-Eboplus Consortium Santoro F Huttner A Dubey S Eichberg M Ndungu FM Kremsner PG Essone PN Agnandji ST Siegrist CA Nakaya HI Ottenhoff THM Haks MC
Lancet Microbe, (2022). 3:e113-e123

Vitamin D Deficiency and Its Association with Iron Deficiency in African Children.Mogire RM Muriuki JM Morovat A Mentzer AJ Webb EL Kimita W Ndungu FM Macharia AW Cutland CL Sirima SB Diarra A Tiono AB Lule SA Madhi SA Prentice AM Bejon P Pettifor JM Elliott AM Adeyemo A Williams TN Atkinson SH
Nutrients, (2022). 14:

TRUE-1: Trial of Repurposed Unithiol for snakebite Envenoming phase 1 (safety, tolerability, pharmacokinetics and pharmacodynamics in healthy Kenyan adults).Abouyannis M FitzGerald R Ngama M Mwangudzah H Nyambura YK Ngome S Riako D Babu L Lewa F Else L Dily Penchala S Orindi B Mumba N Kalama B Ndungu FM Adetifa I Khoo S Lalloo DG Casewell NR Hamaluba M
Wellcome Open Res, (2022). 7:90

Plasmodium falciparum-Specific Memory B-Cell and Antibody Responses Are Associated With Immunity in Children Living in an Endemic Area of Kenya.Jahnmatz P Nyabundi D Sundling C Widman L Mwacharo J Musyoki J Otieno E Ahlborg N Bejon P Ndungu FM Farnert A
Front Immunol, (2022). 13:799306

10-year longitudinal study of malaria in children: Insights into acquisition and maintenance of naturally acquired immunity.Addy JWG Bediako Y Ndungu FM Valetta JJ Reid AJ Mwacharo J Ngoi JM Wambua J Otieno E Musyoki J Said K Berriman M Marsh K Bejon P Recker M Langhorne J
Wellcome Open Res, (2022). 6:79

Chronic Immune Activation and CD4(+) T Cell Lymphopenia in Healthy African Individuals: Perspectives for SARS-CoV-2 Vaccine Efficacy.Wolday D Ndungu FM Gomez-Perez GP de Wit TFR
Front Immunol, (2021). 12:693269

Prevalence and predictors of vitamin D deficiency in young African children.Mogire RM Morovat A Muriuki JM Mentzer AJ Webb EL Kimita W Ndungu FM Macharia AW Cutland CL Sirima SB Diarra A Tiono AB Lule SA Madhi SA Sandhu MS Prentice AM Bejon P Pettifor JM Elliott AM Adeyemo A Williams TN Atkinson SH
BMC Med, (2021). 19:115

Malaria is a cause of iron deficiency in African children.Muriuki JM Mentzer AJ Mitchell R Webb EL Etyang AO Kyobutungi C Morovat A Kimita W Ndungu FM Macharia AW Ngetsa CJ Makale J Lule SA Musani SK Raffield LM Cutland CL Sirima SB Diarra A Tiono AB Fried M Gwamaka M Adu-Afarwuah S Wirth JP Wegmuller R Madhi SA Snow RW Hill AVS Rockett KA Sandhu MS Kwiatkowski DP Prentice AM Byrd KA Ndjebayi A Stewart CP Engle-Stone R Green TJ Karakochuk CD Suchdev PS Bejon P Duffy PE Davey Smith G Elliott AM Williams TN Atkinson SH
Nat Med, (2021). 27:653-658

Atypical B cells are part of an alternative lineage of B cells that participates in responses to vaccination and infection in humans.Sutton HJ Aye R Idris AH Vistein R Nduati E Kai O Mwacharo J Li X Gao X Andrews TD Koutsakos M Nguyen THO Nekrasov M Milburn P Eltahla A Berry AA Kc N Chakravarty S Sim BKL Wheatley AK Kent SJ Hoffman SL Lyke KE Bejon P Luciani F Kedzierska K Seder RA Ndungu FM Cockburn IA
Cell Rep, (2021). 34:108684

Iron Deficiency Is Associated With Reduced Levels of Plasmodium falciparum-specific Antibodies in African Children.Bundi CK Nalwoga A Lubyayi L Muriuki JM Mogire RM Opi H Mentzer AJ Mugyenyi CK Mwacharo J Webb EL Bejon P Williams TN Gikunju JK Beeson JG Elliott AM Ndungu FM Atkinson SH
Clin Infect Dis, (2021). 73:43-49

Malaria exposure drives both cognate and bystander human B cells to adopt an atypical phenotype.Aye R Sutton HJ Nduati EW Kai O Mwacharo J Musyoki J Otieno E Wambua J Bejon P Cockburn IA Ndungu FM
Eur J Immunol, (2020). 50:1187-1194

Estimating the burden of iron deficiency among African children.Muriuki JM Mentzer AJ Webb EL Morovat A Kimita W Ndungu FM Macharia AW Crane RJ Berkley JA Lule SA Cutland C Sirima SB Diarra A Tiono AB Bejon P Madhi SA Hill AVS Prentice AM Suchdev PS Elliott AM Williams TN Atkinson SH
BMC Med, (2020). 18:31

B-cell memory in malaria: Myths and realities.Perez-Mazliah D Ndungu FM Aye R Langhorne J
Immunol Rev, (2020). 293:57-69