Biosciences
Protein-specific immune response elicited by the Shigella sonnei 1790GAHB GMMA-based candidate vaccine in adults with varying exposure to Shigella.Randall AZ, Conti V, Nakakana U, Liang X, Teng AA, Di Pasquale AL, Kapulu M, Frenck RJr, Launay O, Ferruzzi P, Sciré AS, Marchetti E, Obiero C, Pablo JV, Edgar J, Bejon P, Shandling AD, Campo JJ, Yee A, Martin LB, Podda A, Micoli F
mSphere, (2025). :e0105724
Identification of coxsackievirus A24 variant during an acute hemorrhagic conjunctivitis outbreak in coastal Kenya, 2024.Lambisia AW, Mwita Morobe J, Moraa E, Mwarumba S, Korir FKN, Seif Athman R, Kiptui R, Mbee M, Mugo N, Amoth P, Muange P, Houldcroft JC, Barasa E, Mwangangi J, Githinji G, Holmes CE, Ochola-Oyier LI, Agoti CN
Wellcome Open Res, (2025). 10:28
Insecticide resistance intensity in Anopheles gambiae (s.l.) from five malaria epidemiological zones in Kenya.Ramaita E, Agumba S, Mwangangi J, Kitur S, Wachira L, Otieno S, Mburu D, Matoke-Muhia D, Juma E, Mbogo C, Ochomo E, Kamau L
Curr Res Parasitol Vector Borne Dis, (2025). 7:100252
Plasmodium falciparum reticulocyte-binding homologues are targets of human inhibitory antibodies and play a role in immune evasion.Reiling L, Persson KEM, McCallum FJ, Gicheru N, Kinyanjui SM, Chitnis CE, Fowkes FJI, Marsh K, Beeson JG
Front Immunol, (2025). 16:1532451
Rethinking the evidence on COVID-19 in Africa.Bejon P, Agweyu A, Ochola-Oyier LI, Hamaluba M, Kamuya D, Kinyanjui S, Barasa E
Lancet Infect Dis, (2025). 25:S1473-3099
Multiple insecticide resistance in Anopheles funestus from Mopeia, Central Mozambique.Kiuru C, Constantino L, Cole G, Karisa J, Wanjiku C, Okoko M, Candrinho B, Saute F, Rabinovich NR, Chaccour C, Maia MF
Malar J, (2025). 24:81
Through the eyes of the participant: using photovoice to understand the experiences and effects of ivermectin MDA in the context of the BOHEMIA clinical trial in Kwale, Kenya.Onyango T, Nuru K, Kazungu K, Wangari W, Chaccour C, Regina Rabinovich N, Mwangangi J, Maia M, Jones C
Malar J, (2025). 24:79
Development of an oral regimen of unithiol for the treatment of snakebite envenoming: a phase 1 open-label dose-escalation safety trial and pharmacokinetic analysis in healthy Kenyan adults.Abouyannis M, Nyambura YK, Ngome S, Riako D, Musyoki J, Muiruri C, Orindi B, Else L, Amara A, Dickinson L, Clare RH, Albulescu LO, Westhorpe AP, Kool J, Adetifa I, Ndungu FM, FitzGerald R, Khoo S, Lalloo DG, Casewell NR, Hamaluba M
EBioMedicine, (2025). 113:105600
Low-Dose Yellow Fever Vaccine in Adults in Africa.Kimathi D, Juan-Giner A, Bob NS, Orindi B, Namulwana ML, Diatta A, Cheruiyot S, Fall G, Dia M, Hamaluba MM, Nyehangane D, Karanja HK, Gitonga JN, Mugo D, Omuoyo DO, Hussein M, Oloo E, Kamau N, Wafula J, Bendera J, Silvester N, Mwavita J, Joshua M, Mwendwa J, Agababyona C, Ngetsa C, Aisha N, Moki F, Buluku T, Munene M, Mwanga-Amumpaire J, Lutwama J, Kayiwa J, Kamaara E, Barrett AD, Kaleebu P, Bejon P, Sall AA, Grais RF, Warimwe GM
N Engl J Med, (2025). 392:788-797
Beyond mosquitoes and malaria-ivermectin in Africa.Hammann F, Maia MF
Lancet Infect Dis, (2025). 24:S1473-3099
Elevating larval source management as a key strategy for controlling malaria and other vector-borne diseases in Africa.Okumu F, Moore SJ, Selvaraj P, Yafin AH, Juma EO, Shirima GG, Majambere S, Hardy A, Knols BGJ, Msugupakulya BJ, Finda M, Kahamba N, Thomsen E, Ahmed A, Zohdy S, Chaki P, DeChant P, Fornace K, Govella N, Gowelo S, Hakizimana E, Hamainza B, Ijumba JN, Jany W, Kafy HT, Kaindoa EW, Kariuki L, Kiware S, Kweka EJ, Lobo NF, Marrenjo D, Matoke-Muhia D, Mbogo C, McCann RS, Monroe A, Ndenga BA, Ngowo HS, Ochomo E, Opiyo M, Reithinger R, Sikaala CH, Tatarsky A, Takudzwa D, Trujillano F, Sherrard-Smith E
Parasit Vectors, (2025). 18:45
Detection of low frequency artemisinin resistance mutations, C469Y, P553L and A675V, and fixed antifolate resistance mutations in asymptomatic primary school children in Kenya.Osoti V, Wamae K, Ndwiga L, Gichuki PM, Okoyo C, Kepha S, Keitany K, Kandie R, Aricha S, Kiplagat R, Mwandawiro C, Bejon P, Snow RW, Ochola-Oyier LI
BMC Infect Dis, (2025). 25:73
Identification of novel PfEMP1 variants containing domain cassettes 11, 15 and 8 that mediate the Plasmodium falciparum virulence-associated rosetting phenotype.McLean FE, Omondi BR, Diallo N, Otoboh S, Kifude C, Abdi A, Lim R, Otto TD, Ghumra A, Rowe JA
PLoS Pathog, (2025). 21:e1012434
Regional action needed to halt antimalarial drug resistance in Africa.Martinez-Vega R, Ishengoma DS, Gosling R, Rosenthal PJ, Dondorp A, Barnes KI, Nsanzabana C, Djimde AA, Ochola-Oyier LI, Tibenderana J, Chimumbwa J, Golassa L, Kapologwe NA, Mbacham WF, Kamya MR, Fidock DA, Komatsu R, von Seidlein L, Dhorda M
Lancet, (2025). 405:7-10
Ivermectin to Control Malaria — A Cluster-Randomized Trial.Chaccour C, Maia M, Kariuki M, Ruiz-Castillo P, Wanjiku C, Kasiwa L, Brazeal A, Casellas A, Ngama M, Onyango T, Elobolobo E, Kazungu K, Mael M, Wangari W, Nuru K, Otuko R, Sanz A, Ringera I, Matano A, Mitora S, Ribes M, Brew J, Gorski N, Nicolas P, Stanulovic S, Omondi I, Furnival-Adams J, Túnez L, Mbarak J, Vegove V, Yaa E, Mramba S, Kibet Y, Nyambura N, Rotich C, Wanjiru S, Vura M, Wanjiku F, Sam L, Collins L, Xia K, Hammann F, Saúte F, Rudd M, Rist C, Jones C, Mwangangi J, Rabinovich NR
New England Journal of Medicine, (2025). 393:362-375
Malaria Chemotherapeutics What Next for Africa.Ochola L, Gitaka J, Kanoi B, Kimani CN, Akala HM, Alfred MO, Ochola-Oyier LI, Ogutu B
Advanced Therapeutics, (2025). 8:2400453
Comparative performance of the InBios SCoV-2 Detect (TM) IgG ELISA and the in-house KWTRP ELISA in detecting SARS-CoV-2 spike IgG antibodies in Kenyan populations.Kutima B, Kagucia EW, Mwai K, Kimani M, Sigilai A, Mugo D, Karanja H, Gitonga JN, Karani A, Akech D, Toroitich M, Karia B, Tuju J, Ziraba AK, Bigogo G, Ochieng C, Onyango C, Lidechi S, Munywoki PK, Uyoga S, Adetifa IMO, Oyier LIO, Bejon P, Scott JAG, Agweyu A, Warimwe GM, Nyagwange J
Wellcome Open Res, (2024). 9:349
Profile: The Kenya Multi-Site Serosurveillance (KEMIS) collaboration.Kagucia EW, Voller S, Ziraba AK, Bigogo G, Munywoki PK, Makobu K, Nokes DJ, Nyagwange J, Orlendo C, Akech D, Sigilai A, Onyango C, Juma B, Herman-Roloff A, Munyua P, Apondi C, Lidechi S, Audi A, Ouma A, Aol G, Misore T, Nasimiyu C, Onyango D, Lo T, Kasera K, Jalang'o R, Kingwara L, Adetifa I, Etyang AO, Warimwe G, Agweyu A, Scott JAG
Gates Open Res, (2024). 8:60
Evaluation of population immunity against SARS-CoV-2 variants, EG.5.1, FY.4, BA.2.86, JN.1, JN.1.4, and KP.3.1.1 using samples from two health demographic surveillance systems in Kenya.Lugano D, Kutima B, Kimani M, Sigilai A, Gitonga J, Karani A, Akech D, Karia B, Ziraba AK, Maina A, Lambisia A, Omuoyo D, Mugo D, Lucinde R, Owuor S, Konyino G, Newman J, Bailey D, Nduati E, Githinji G, Agoti CN, Bejon P, Scott JAG, Agweyu A, Kagucia W, Warimwe GM, Sande C, Ochola-Oyier LI, Nyagwange J
BMC Infect Dis, (2024). 24:1474
Systemic biological mechanisms underpin poor post-discharge growth among severely wasted children with HIV.Mudibo EO, Bogaert J, Tigoi C, Ngari MM, Singa BO, Lancioni CL, Diallo AH, Mbale E, Mupere E, Mukisa J, Thitiri J, Timbwa M, Omer E, Ngao N, Musyimi R, Kahindi E, Bamouni RM, Bandsma RHJ, Kelly P, Prendergast AJ, McGrath CJ, Tickell KD, Walson JL, Berkley JA, Njunge JM, Gonzales GB
Nat Commun, (2024). 15:10299
