Francis Ndungu

The ferroportin Q248H mutation protects from anemia, but not malaria or bacteremia.Muriuki JM Mentzer AJ Band G Gilchrist JJ Carstensen T Lule SA Goheen MM Joof F Kimita W Mogire R Cutland CL Diarra A Rautanen A Pomilla C Gurdasani D Rockett K Mturi N Ndungu FM Scott JAG Sirima SB Morovat A Prentice AM Madhi SA Webb EL Elliott AM Bejon P Sandhu MS Hill AVS Kwiatkowski DP Williams TN Cerami C Atkinson SH
Sci Adv, (2019). 5:eaaw0109

A seven-year study on the effect of the pre-erythrocytic malaria vaccine candidate RTS,S/AS01 (E) on blood stage immunity in young Kenyan children.Ndungu FM Mwacharo J Wambua J Njuguna P Marsh K Drakeley C Bejon P
Wellcome Open Res, (2019). 4:42

Repeated clinical malaria episodes are associated with modification of the immune system in children.Bediako Y Adams R Reid AJ Valletta JJ Ndungu FM Sodenkamp J Mwacharo J Ngoi JM Kimani D Kai O Wambua J Nyangweso G de Villiers EP Sanders M Lotkowska ME Lin JW Manni S Addy JWG Recker M Newbold C Berriman M Bejon P Marsh K Langhorne J
BMC Med, (2019). 17:60

Longitudinal Analysis of Infant Stool Bacteria Communities Before and After Acute Febrile Malaria and Artemether-Lumefantrine Treatment.Mandal RK Crane RJ Berkley JA Gumbi W Wambua J Ngoi JM Ndungu FM Schmidt NW
J Infect Dis, (2019). 220:687-698

Iron Status and Associated Malaria Risk Among African Children.Muriuki JM Mentzer AJ Kimita W Ndungu FM Macharia AW Webb EL Lule SA Morovat A Hill AVS Bejon P Elliott AM Williams TN Atkinson SH
Clin Infect Dis, (2019). 68:1807-1814

Determinants of antibody persistence across doses and continents after single-dose rVSV-ZEBOV vaccination for Ebola virus disease: an observational cohort study.Huttner A Agnandji ST Combescure C Fernandes JF Bache EB Kabwende L Ndungu FM Brosnahan J Monath TP Lemaitre B Grillet S Botto M Engler O Portmann J Siegrist D Bejon P Silvera P Kremsner P Siegrist CA Vebcon, Vsv Ebovac Vsv-Eboplus Consortia
Lancet Infect Dis, (2018). 18:738-748

Public antibodies to malaria antigens generated by two LAIR1 insertion modalities.Pieper K Tan J Piccoli L Foglierini M Barbieri S Chen Y Silacci-Fregni C Wolf T Jarrossay D Anderle M Abdi A Ndungu FM Doumbo OK Traore B Tran TM Jongo S Zenklusen I Crompton PD Daubenberger C Bull PC Sallusto F Lanzavecchia A
Nature, (2017). 548:597-601

The effect of declining exposure on T cell-mediated immunity to Plasmodium falciparum - an epidemiological "natural experiment".Bediako Y Ngoi JM Nyangweso G Wambua J Opiyo M Nduati EW Bejon P Marsh K Ndungu FM
BMC Med, (2016). 14:143

Identifying children with excess malaria episodes after adjusting for variation in exposure: identification from a longitudinal study using statistical count models.Ndungu FM Marsh K Fegan G Wambua J Nyangweso G Ogada E Mwangi T Nyundo C Macharia A Uyoga S Williams TN Bejon P
BMC Med, (2015). 13:183

Avidity of anti-circumsporozoite antibodies following vaccination with RTS,S/AS01E in young children.Olotu A Clement F Jongert E Vekemans J Njuguna P Ndungu FM Marsh K Leroux-Roels G Bejon P
PLoS One, (2014). 9:e115126

Chronic exposure to Plasmodium falciparum is associated with phenotypic evidence of B and T cell exhaustion.Illingworth J Butler NS Roetynck S Mwacharo J Pierce SK Bejon P Crompton PD Marsh K Ndungu FM
J Immunol, (2013). 190:1038-47

Lack of avidity maturation of merozoite antigen-specific antibodies with increasing exposure to Plasmodium falciparum amongst children and adults exposed to endemic malaria in Kenya.Ibison F Olotu A Muema DM Mwacharo J Ohuma E Kimani D Marsh K Bejon P Ndungu FM
PLoS One, (2012). 7:e52939

A statistical interaction between circumsporozoite protein-specific T cell and antibody responses and risk of clinical malaria episodes following vaccination with RTS,S/AS01E.Ndungu FM Mwacharo J Kimani D Kai O Moris P Jongert E Vekemans J Olotu A Bejon P
PLoS One, (2012). 7:e52870

Memory B cells are a more reliable archive for historical antimalarial responses than plasma antibodies in no-longer exposed children.Ndungu FM Olotu A Mwacharo J Nyonda M Apfeld J Mramba LK Fegan GW Bejon P Marsh K
Proc Natl Acad Sci U S A, (2012). 109:8247-52

High efficiency human memory B cell assay and its application to studying Plasmodium falciparum-specific memory B cells in natural infections.Weiss GE Ndungu FM McKittrick N Li S Kimani D Crompton PD Marsh K Pierce SK
J Immunol Methods, (2012). 375:68-74

Effect of HIV infection on the acute antibody response to malaria antigens in children: an observational study.Muema DK Ndungu FM Kinyanjui SM Berkley JA
Malar J, (2011). 10:55

Distinct kinetics of memory B-cell and plasma-cell responses in peripheral blood following a blood-stage Plasmodium chabaudi infection in mice.Nduati EW Ng DH Ndungu FM Gardner P Urban BC Langhorne J
PLoS One, (2010). 5:e15007

Germinal centre and marginal zone B cells expand quickly in a second Plasmodium chabaudi malaria infection producing mature plasma cells.Stephens R Ndungu FM Langhorne J
Parasite Immunol, (2009). 31:20-31

Immunity to malaria: more questions than answers.Langhorne J Ndungu FM Sponaas AM Marsh K
Nat Immunol, (2008). 9:725-32

CD4 T cells from malaria-nonexposed individuals respond to the CD36-Binding Domain of Plasmodium falciparum erythrocyte membrane protein-1 via an MHC class II-TCR-independent pathway.Ndungu FM Sanni L Urban B Stephens R Newbold CI Marsh K Langhorne J
J Immunol, (2006). 176:5504-12