Francis Ndungu
Memory B-Cell Responses Against Merozoite Antigens After Acute Plasmodium falciparum Malaria, Assessed Over One Year Using a Novel Multiplexed FluoroSpot Assay.Jahnmatz P, Sundling C, Yman V, Widman L, Asghar M, Sonden K, Stenstrom C, Smedman C, Ndungu F, Ahlborg N, Farnert A
Front Immunol, (2020). 11:619398
Malaria exposure drives both cognate and bystander human B cells to adopt an atypical phenotype.Aye R, Sutton HJ, Nduati EW, Kai O, Mwacharo J, Musyoki J, Otieno E, Wambua J, Bejon P, Cockburn IA, Ndungu FM
Eur J Immunol, (2020). 50:1187-1194
Estimating the burden of iron deficiency among African children.Muriuki JM, Mentzer AJ, Webb EL, Morovat A, Kimita W, Ndungu FM, Macharia AW, Crane RJ, Berkley JA, Lule SA, Cutland C, Sirima SB, Diarra A, Tiono AB, Bejon P, Madhi SA, Hill AVS, Prentice AM, Suchdev PS, Elliott AM, Williams TN, Atkinson SH
BMC Med, (2020). 18:31
B-cell memory in malaria: Myths and realities.Perez-Mazliah D, Ndungu FM, Aye R, Langhorne J
Immunol Rev, (2020). 293:57-69
The ferroportin Q248H mutation protects from anemia, but not malaria or bacteremia.Muriuki JM, Mentzer AJ, Band G, Gilchrist JJ, Carstensen T, Lule SA, Goheen MM, Joof F, Kimita W, Mogire R, Cutland CL, Diarra A, Rautanen A, Pomilla C, Gurdasani D, Rockett K, Mturi N, Ndungu FM, Scott JAG, Sirima SB, Morovat A, Prentice AM, Madhi SA, Webb EL, Elliott AM, Bejon P, Sandhu MS, Hill AVS, Kwiatkowski DP, Williams TN, Cerami C, Atkinson SH
Sci Adv, (2019). 5:eaaw0109
A seven-year study on the effect of the pre-erythrocytic malaria vaccine candidate RTS,S/AS01 E on blood stage immunity in young Kenyan children.Ndungu FM, Mwacharo J, Wambua J, Njuguna P, Marsh K, Drakeley C, Bejon P
Wellcome Open Res, (2019). 4:42
Repeated clinical malaria episodes are associated with modification of the immune system in children.Bediako Y, Adams R, Reid AJ, Valletta JJ, Ndungu FM, Sodenkamp J, Mwacharo J, Ngoi JM, Kimani D, Kai O, Wambua J, Nyangweso G, de Villiers EP, Sanders M, Lotkowska ME, Lin JW, Manni S, Addy JWG, Recker M, Newbold C, Berriman M, Bejon P, Marsh K, Langhorne J
BMC Med, (2019). 17:60
Longitudinal Analysis of Infant Stool Bacteria Communities Before and After Acute Febrile Malaria and Artemether-Lumefantrine Treatment.Mandal RK, Crane RJ, Berkley JA, Gumbi W, Wambua J, Ngoi JM, Ndungu FM, Schmidt NW
J Infect Dis, (2019). 220:687-698
Transmission and Age Impact the Risk of Developing Febrile Malaria in Children with Asymptomatic Plasmodium falciparum Parasitemia.Wamae K, Wambua J, Nyangweso G, Mwambingu G, Osier F, Ndung'u F, Bejon P, Ochola-Oyier LI
J Infect Dis, (2019). 219:936-944
Iron Status and Associated Malaria Risk Among African Children.Muriuki JM, Mentzer AJ, Kimita W, Ndungu FM, Macharia AW, Webb EL, Lule SA, Morovat A, Hill AVS, Bejon P, Elliott AM, Williams TN, Atkinson SH
Clin Infect Dis, (2019). 68:1807-1814
Determinants of antibody persistence across doses and continents after single-dose rVSV-ZEBOV vaccination for Ebola virus disease: an observational cohort study.Huttner A, Agnandji ST, Combescure C, Fernandes JF, Bache EB, Kabwende L, Ndungu FM, Brosnahan J, Monath TP, Lemaitre B, Grillet S, Botto M, Engler O, Portmann J, Siegrist D, Bejon P, Silvera P, Kremsner P, Siegrist CA, VEBCON, VSV-EBOVAC, VSV-EBOPLUS Consortia
Lancet Infect Dis, (2018). 18:738-748
Public antibodies to malaria antigens generated by two LAIR1 insertion modalities.Pieper K, Tan J, Piccoli L, Foglierini M, Barbieri S, Chen Y, Silacci-Fregni C, Wolf T, Jarrossay D, Anderle M, Abdi A, Ndungu FM, Doumbo OK, Traore B, Tran TM, Jongo S, Zenklusen I, Crompton PD, Daubenberger C, Bull PC, Sallusto F, Lanzavecchia A
Nature, (2017). 548:597-601
The effect of declining exposure on T cell-mediated immunity to Plasmodium falciparum - an epidemiological "natural experiment. .Bediako Y, Ngoi JM, Nyangweso G, Wambua J, Opiyo M, Nduati EW, Bejon P, Marsh K, Ndungu FM
BMC Med, (2016). 14:143
A LAIR1 insertion generates broadly reactive antibodies against malaria variant antigens.Tan J, Pieper K, Piccoli L, Abdi A, Perez MF, Geiger R, Tully CM, Jarrossay D, Maina Ndungu F, Wambua J, Bejon P, Fregni CS, Fernandez-Rodriguez B, Barbieri S, Bianchi S, Marsh K, Thathy V, Corti D, Sallusto F, Bull P, Lanzavecchia A
Nature, (2016). 529:105-109
Identifying children with excess malaria episodes after adjusting for variation in exposure: identification from a longitudinal study using statistical count models.Ndungu FM, Marsh K, Fegan G, Wambua J, Nyangweso G, Ogada E, Mwangi T, Nyundo C, Macharia A, Uyoga S, Williams TN, Bejon P
BMC Med, (2015). 13:183
Avidity of anti-circumsporozoite antibodies following vaccination with RTS,S/AS01E in young children.Olotu A, Clement F, Jongert E, Vekemans J, Njuguna P, Ndungu FM, Marsh K, Leroux-Roels G, Bejon P
PLoS One, (2014). 9:e115126
Chronic exposure to Plasmodium falciparum is associated with phenotypic evidence of B and T cell exhaustion.Illingworth J, Butler NS, Roetynck S, Mwacharo J, Pierce SK, Bejon P, Crompton PD, Marsh K, Ndungu FM
J Immunol, (2013). 190:1038-47
Lack of avidity maturation of merozoite antigen-specific antibodies with increasing exposure to Plasmodium falciparum amongst children and adults exposed to endemic malaria in Kenya.Ibison F, Olotu A, Muema DM, Mwacharo J, Ohuma E, Kimani D, Marsh K, Bejon P, Ndungu FM
PLoS One, (2012). 7:e52939
A statistical interaction between circumsporozoite protein-specific T cell and antibody responses and risk of clinical malaria episodes following vaccination with RTS,S/AS01E.Ndungu FM, Mwacharo J, Kimani D, Kai O, Moris P, Jongert E, Vekemans J, Olotu A, Bejon P
PLoS One, (2012). 7:e52870
Memory B cells are a more reliable archive for historical antimalarial responses than plasma antibodies in no-longer exposed children.Ndungu FM, Olotu A, Mwacharo J, Nyonda M, Apfeld J, Mramba LK, Fegan GW, Bejon P, Marsh K
Proc Natl Acad Sci U S A, (2012). 109:8247-52
