biosciences/Wellcome Open Res

An optimization of four SARS-CoV-2 qRT-PCR assays in a Kenyan laboratory to support the national COVID-19 rapid response teams.Mohammed, K. S. de Laurent, Z. R. Omuoyo, D. O. Lewa, C. Gicheru, E. Cheruiyot, R. Bartilol, B. Mutua, S. Musyoki, J. Gumba, H. Mwacharo, J. Riako, D. Mwangi, S. J. Gichuki, B. M. Nyamako, L. Karani, A. Karanja, H. Mugo, D. Gitonga, J. N. Njuguna, S. Gumbi, W. Tawa, B. Tendwa, M. Cheruiyot, W. Sein, Y. Nyambu, J. K. Patta, S. O. Thani, T. S. Maitha, E. K. Kitole, B. Mwakinangu, M. S. Muslih, B. S. Otieno, J. O. Nyiro, J. U. Kiyuka, P. Ndwiga, L. Wamae, K. Kimani, D. Makale, J. Morobe, J. M. Osoti, V. Lambisia, A. W. Odundo, C. Mwarumba, S. Mutunga, M. Bejon, P. Tsofa, B. Agoti, C. N. Ochola-Oyier, L. I.
Wellcome Open Res, (2020). 5:162

Plasma calprotectin as a biomarker of mortality at antiretroviral treatment initiation in advanced HIV - pilot study.Kamau, F. W. Gwela, A. Nyerere, A. K. Riitho, V. Njunge, J. M. Ngari, M. M. Prendergast, A. J. Berkley, J. A.
Wellcome Open Res, (2020). 5:46

Pooled testing conserves SARS-CoV-2 laboratory resources and improves test turn-around time: experience on the Kenyan Coast.Agoti, C. N. Mutunga, M. Lambisia, A. W. Kimani, D. Cheruiyot, R. Kiyuka, P. Lewa, C. Gicheru, E. Tendwa, M. Said Mohammed, K. Osoti, V. Makale, J. Tawa, B. Odundo, C. Cheruiyot, W. Nyamu, W. Gumbi, W. Mwacharo, J. Nyamako, L. Otieno, E. Amadi, D. Thoya, J. Karani, A. Mugo, D. Musyoki, J. Gumba, H. Mwarumba, S. M. Gichuki B Njuguna, S. Riako, D. Mutua, S. Gitonga, J. N. Sein, Y. Bartilol, B. Mwangi, S. J. O. Omuoyo D M. Morobe J de Laurent, Z. R. Bejon, P. Ochola-Oyier, L. I. Tsofa, B.
Wellcome Open Res, (2020). 5:186

Interferon-gamma polymorphisms and risk of iron deficiency and anaemia in Gambian children.Abuga, K. M. Rockett, K. A. Muriuki, J. M. Koch, O. Nairz, M. Sirugo, G. Bejon, P. Kwiatkowski, D. P. Prentice, A. M. Atkinson, S. H.
Wellcome Open Res, (2020). 5:40

Cost-effectiveness of oral versus intravenous antibiotics (OVIVA) in patients with bone and joint infection: evidence from a non-inferiority trial.McMeekin, N. Geue, C. Briggs, A. Rombach, I. Li, H. K. Bejon, P. McNally, M. Atkins, B. L. Ferguson, J. Scarborough, M. Oviva collaborators
Wellcome Open Res, (2019). 4:108

Bayesian evaluation of the performance of three diagnostic tests for Plasmodium falciparum infection in a low-transmission setting in Kilifi County, Kenya.Mweu, M. M. Wambua, J. Njuga, F. Bejon, P. Mwanga, D.
Wellcome Open Res, (2019). 4:67

Gametocyte carriage in an era of changing malaria epidemiology: A 19-year analysis of a malaria longitudinal cohort.Muthui, M. K. Mogeni, P. Mwai, K. Nyundo, C. Macharia, A. Williams, T. N. Nyangweso, G. Wambua, J. Mwanga, D. Marsh, K. Bejon, P. Kapulu, M. C.
Wellcome Open Res, (2019). 4:66

A seven-year study on the effect of the pre-erythrocytic malaria vaccine candidate RTS,S/AS01 (E) on blood stage immunity in young Kenyan children.Ndungu, F. M. Mwacharo, J. Wambua, J. Njuguna, P. Marsh, K. Drakeley, C. Bejon, P.
Wellcome Open Res, (2019). 4:42

Long read assemblies of geographically dispersed Plasmodium falciparum isolates reveal highly structured subtelomeres.Otto, T. D. Bohme, U. Sanders, M. Reid, A. Bruske, E. I. Duffy, C. W. Bull, P. C. Pearson, R. D. Abdi, A. Dimonte, S. Stewart, L. B. Campino, S. Kekre, M. Hamilton, W. L. Claessens, A. Volkman, S. K. Ndiaye, D. Amambua-Ngwa, A. Diakite, M. Fairhurst, R. M. Conway, D. J. Franck, M. Newbold, C. I. Berriman, M.
Wellcome Open Res, (2018). 3:52

Ethical considerations in Controlled Human Malaria Infection studies in low resource settings: Experiences and perceptions of study participants in a malaria Challenge study in Kenya.Njue, M. Njuguna, P. Kapulu, M. C. Sanga, G. Bejon, P. Marsh, V. Molyneux, S. Kamuya, D.
Wellcome Open Res, (2018). 3:39

Variation in the effectiveness of insecticide treated nets against malaria and outdoor biting by vectors in Kilifi, Kenya.Kamau, A. Mwangangi, J. M. Rono, M. K. Mogeni, P. Omedo, I. Midega, J. Scott, J. A. G. Bejon, P.
Wellcome Open Res, (2017). 2:22

Amodiaquine resistance in Plasmodium berghei is associated with PbCRT His95Pro mutation, loss of chloroquine, artemisinin and primaquine sensitivity, and high transcript levels of key transporters.Ndung'u, L. Langat, B. Magiri, E. Ng'ang'a, J. Irungu, B. Nzila, A. Kiboi, D.
Wellcome Open Res, (2017). 2:44

A framework for Controlled Human Infection Model (CHIM) studies in Malawi: Report of a Wellcome Trust workshop on CHIM in Low Income Countries held in Blantyre, Malawi.Gordon, S. B. Rylance, J. Luck, A. Jambo, K. Ferreira, D. M. Manda-Taylor, L. Bejon, P. Ngwira, B. Littler, K. Seager, Z. Gibani, M. Gmeiner, M. Roestenberg, M. Mlombe, Y. Wellcome Trust, Chim workshop participants
Wellcome Open Res, (2017). 2:70

Proteomic analysis of extracellular vesicles from a Plasmodium falciparum Kenyan clinical isolate defines a core parasite secretome.Abdi, A. Yu, L. Goulding, D. Rono, M. K. Bejon, P. Choudhary, J. Rayner, J.
Wellcome Open Res, (2017). 2:50

Geographic-genetic analysis of Plasmodium falciparum parasite populations from surveys of primary school children in Western Kenya.Omedo, I. Mogeni, P. Rockett, K. Kamau, A. Hubbart, C. Jeffreys, A. Ochola-Oyier, L. I. de Villiers, E. P. Gitonga, C. W. Noor, A. M. Snow, R. W. Kwiatkowski, D. Bejon, P.
Wellcome Open Res, (2017). 2:29

A geo-coded inventory of anophelines in the Afrotropical Region south of the Sahara: 1898-2016.Kyalo, D. Amratia, P. Mundia, C. W. Mbogo, C. M. Coetzee, M. Snow, R. W.
Wellcome Open Res, (2017). 2:57

Micro-epidemiological structuring of Plasmodium falciparum parasite populations in regions with varying transmission intensities in Africa.Omedo, I. Mogeni, P. Bousema, T. Rockett, K. Amambua-Ngwa, A. Oyier, I. C. Stevenson J Y. Baidjoe A de Villiers, E. P. Fegan, G. Ross, A. Hubbart, C. Jeffreys, A. N. Williams T Kwiatkowski, D. Bejon, P.
Wellcome Open Res, (2017). 2:10