Nairobi Programme

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Dr. Sam Akech

Principal Investigator


Current Work

His main research interests are; • Understanding the aetiology, management, and impact of interventions in children with severe febrile illnesses, focussing on malaria and severe infections • Improving triage and treatment of children with febrile illnesses presenting to hospitals • Antimicrobial resistance (AMR) in paediatric inpatient settings • Hospital inpatient surveillance for understanding impact of interventions and burden of diseases in children The studies inform case management of common childhood infections which lead to admission while also identifying areas that need further research evidence. He has led the sentinel surveillance in Kenya for the WHO-led evaluation of RTS, S/AS01 malaria vaccine following its pilot introduction in 2019 in Kenya, Ghana, Malawi. He leads the childhood severe febrile illness study group (cSEFI Group) within the Nairobi hub of KWTRP. He also supported publication of evidence briefs on COVID-19 that supported Kenya’s MoH response to COVID-19. Research Projects • An evaluation of the cluster-randomised pilot implementation of the RTS, S/AS01 malaria vaccine through routine health systems in western Kenya: a post-authorization observational study • The CINAMR (Clinical Information Network-Antimicrobial Resistance) Project: A pilot microbial surveillance using hospitals linked to regional laboratories in Kenya • Strengthening the evidence for policy on the RTS,S/AS01 malaria vaccine: assessment of safety and effectiveness using case-control studies embedded in the Malaria Vaccine Pilot Evaluation • A Clinically Oriented Antimicrobial Resistance Network (ACORN 2.0) • Triage and management of sepsis in children using the point-of-care Paediatric Rapid Sepsis Trigger tool

Collaborations

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