Bioscience

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Dr Abdirahman Abdi

Principal Investigator


Publications

Maintenance of high temporal Plasmodium falciparum genetic diversity and complexity of infection in asymptomatic and symptomatic infections in Kilifi, Kenya from 2007 to 2018.
Kimenyi, K. M., Wamae, K., Ngoi, J. M., de Laurent, Z. R., Ndwiga, L., Osoti, V., Obiero, G., Abdi, A. I., Bejon, P., Ochola-Oyier, L. I.
Malar J, (2022). 21:192

Breadth of Antibodies to Plasmodium falciparum Variant Surface Antigens Is Associated With Immunity in a Controlled Human Malaria Infection Study.
Kimingi, H. W., Kinyua, A. W., Achieng, N. A., Wambui, K. M., Mwangi, S., Nguti, R., Kivisi, C. A., Jensen, A. T. R., Bejon, P., Kapulu, M. C., Abdi, A. I., Kinyanjui, S. M., CHMI-SIKA Study Team
Front Immunol, (2022). 13:894770

Analysis of var Gene Transcription Pattern Using DBLalpha Tags.
Andisi, K. C., Abdi, A. I.
Methods Mol Biol, (2022). 2470:173-184

Extracellular vesicles isolated from milk can improve gut barrier dysfunction induced by malnutrition.
Maghraby, M. K., Li, B., Chi, L., Ling, C., Benmoussa, A., Provost, P., Postmus, A. C., Abdi, A., Pierro, A., Bourdon, C., Bandsma, R. H. J.
Sci Rep, (2021). 11:7635

Antigenic cartography of immune responses to Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1).
Tuju, J., Mackinnon, M. J., Abdi, A. I., Karanja, H., Musyoki, J. N., Warimwe, G. M., Gitau, E. N., Marsh, K., Bull, P. C., Urban, B. C.
PLoS Pathog, (2019). 15:e1007870

No evidence of P. falciparum K13 artemisinin conferring mutations over a 24-year analysis in Coastal Kenya, but a near complete reversion to chloroquine wild type parasites.
Wamae, K., Okanda, D., Ndwiga, L., Osoti, V., Kimenyi, K. M., Abdi, A. I., Bejon, P., Sutherland, C., Ochola-Oyier, L. I.
Antimicrob Agents Chemother, (2019). :

Exploring Plasmodium falciparum Var Gene Expression to Assess Host Selection Pressure on Parasites During Infancy.
Kivisi, C. A., Muthui, M., Hunt, M., Fegan, G., Otto, T. D., Githinji, G., Warimwe, G. M., Rance, R., Marsh, K., Bull, P. C., Abdi, A. I.
Front Immunol, (2019). 10:2328

Long read assemblies of geographically dispersed Plasmodium falciparum isolates reveal highly structured subtelomeres.
Otto, T. D., Bohme, U., Sanders, M., Reid, A., Bruske, E. I., Duffy, C. W., Bull, P. C., Pearson, R. D., Abdi, A., Dimonte, S., Stewart, L. B., Campino, S., Kekre, M., Hamilton, W. L., Claessens, A., Volkman, S. K., Ndiaye, D., Amambua-Ngwa, A., Diakite, M., Fairhurst, R. M., Conway, D. J., Franck, M., Newbold, C. I., Berriman, M.
Wellcome Open Res, (2018). 3:52

Plasmodium falciparum malaria parasite var gene expression is modified by host antibodies: longitudinal evidence from controlled infections of Kenyan adults with varying natural exposure.
Abdi, A. I., Hodgson, S. H., Muthui, M. K., Kivisi, C. A., Kamuyu, G., Kimani, D., Hoffman, S. L., Juma, E., Ogutu, B., Draper, S. J., Osier, F., Bejon, P., Marsh, K., Bull, P. C.
BMC Infect Dis, (2017). 17:585

Proteomic analysis of extracellular vesicles from a Plasmodium falciparum Kenyan clinical isolate defines a core parasite secretome.
Abdi, A., Yu, L., Goulding, D., Rono, M. K., Bejon, P., Choudhary, J., Rayner, J.
Wellcome Open Res, (2017). 2:50