Bioscience

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Dr Eunice Nduati

Principal Investigator


Publications

Chlorproguanil-dapsone for treatment of drug-resistant falciparum malaria in Tanzania.
Mutabingwa, T., Nzila, A., Mberu, E., Nduati, E., Winstanley, P., Hills, E., Watkins, W.
Lancet, (2001). 358:1218-23

Plasmodium falciparum: in vitro activity of sulfadoxine and dapsone in field isolates from Kenya: point mutations in dihydropteroate synthase may not be the only determinants in sulfa resistance.
Mberu, E. K., Nzila, A. M., Nduati, E., Ross, A., Monks, S. M., Kokwaro, G. O., Watkins, W. M., Hopkins Sibley, C.
Exp Parasitol, (2002). 101:90-6

Genetic diversity of Plasmodium falciparum parasites from Kenya is not affected by antifolate drug selection.
Nzila, A. M., Mberu, E. K., Nduati, E., Ross, A., Watkins, W. M., Sibley, C. H.
Int J Parasitol, (2002). 32:1469-76

In vitro activities of 2,4-diaminoquinazoline and 2,4-diaminopteridine derivatives against Plasmodium falciparum.
Ommeh, S., Nduati, E., Mberu, E., Kokwaro, G., Marsh, K., Rosowsky, A., Nzila, A.
Antimicrob Agents Chemother, (2004). 48:3711-4

Why has the dihydrofolate reductase 164 mutation not consistently been found in Africa yet?.
Nzila, A., Ochong, E., Nduati, E., Gilbert, K., Winstanley, P., Ward, S., Marsh, K.
Trans R Soc Trop Med Hyg, (2005). 99:341-6

2,4-diaminopteridine-based compounds as precursors for de novo synthesis of antifolates: a novel class of antimalarials.
Nduati, E., Hunt, S., Kamau, E. M., Nzila, A.
Antimicrob Agents Chemother, (2005). 49:3652-7

Effect of folate derivatives on the activity of antifolate drugs used against malaria and cancer.
Nduati, E., Diriye, A., Ommeh, S., Mwai, L., Kiara, S., Masseno, V., Kokwaro, G., Nzila, A.
Parasitol Res, (2008). 102:1227-34

Distinct kinetics of memory B-cell and plasma-cell responses in peripheral blood following a blood-stage Plasmodium chabaudi infection in mice.
Nduati, E. W., Ng, D. H., Ndungu, F. M., Gardner, P., Urban, B. C., Langhorne, J.
PLoS One, (2010). 5:e15007