Eunice Nduati

Effect of folate derivatives on the activity of antifolate drugs used against malaria and cancer.Nduati E, Diriye A, Ommeh S, Mwai L, Kiara S, Masseno V, Kokwaro G, Nzila A
Parasitol Res, (2008). 102:1227-34

Multiple synergistic interactions between atovaquone and antifolates against Plasmodium falciparum in vitro: a rational basis for combination therapy.Nduati EW, Kamau EM
Acta Trop, (2006). 97:357-63

2,4-diaminopteridine-based compounds as precursors for de novo synthesis of antifolates: a novel class of antimalarials.Nduati E, Hunt S, Kamau EM, Nzila A
Antimicrob Agents Chemother, (2005). 49:3652-7

Why has the dihydrofolate reductase 164 mutation not consistently been found in Africa yet?.Nzila A, Ochong E, Nduati E, Gilbert K, Winstanley P, Ward S, Marsh K
Trans R Soc Trop Med Hyg, (2005). 99:341-6

In vitro activities of 2,4-diaminoquinazoline and 2,4-diaminopteridine derivatives against Plasmodium falciparum.Ommeh S, Nduati E, Mberu E, Kokwaro G, Marsh K, Rosowsky A, Nzila A
Antimicrob Agents Chemother, (2004). 48:3711-4

Plasmodium falciparum: in vitro activity of sulfadoxine and dapsone in field isolates from Kenya: point mutations in dihydropteroate synthase may not be the only determinants in sulfa resistance.Mberu EK, Nzila AM, Nduati E, Ross A, Monks SM, Kokwaro GO, Watkins WM, Hopkins Sibley C
Exp Parasitol, (2002). 101:90-6

Genetic diversity of Plasmodium falciparum parasites from Kenya is not affected by antifolate drug selection.Nzila AM, Mberu EK, Nduati E, Ross A, Watkins WM, Sibley CH
Int J Parasitol, (2002). 32:1469-76

Chlorproguanil-dapsone for treatment of drug-resistant falciparum malaria in Tanzania.Mutabingwa T, Nzila A, Mberu E, Nduati E, Winstanley P, Hills E, Watkins W
Lancet, (2001). 358:1218-23

Molecular evidence of greater selective pressure for drug resistance exerted by the long-acting antifolate Pyrimethamine/Sulfadoxine compared with the shorter-acting chlorproguanil/dapsone on Kenyan Plasmodium falciparum.Nzila AM, Nduati E, Mberu EK, Hopkins Sibley C, Monks SA, Winstanley PA, Watkins WM
J Infect Dis, (2000). 181:2023-8