Abstract

Brucellosis: imported and laboratory-acquired cases, and an overview of treatment trials

Luzzi, G. A. Brindle, R. Sockett, P. N. Solera, J. Klenerman, P. Warrell, D. A.
Trans R Soc Trop Med Hyg. 1993; 87138-41

Permanent descriptor

https://doi.org/10.1016/0035-9203(93)90460-8

Following the successful eradication of Brucella abortus infection in cattle, human brucellosis in England and Wales has become an uncommon imported disease. Culture of the organism presents a major laboratory hazard, and difficulties in identification may occur using a biochemical test-strip method. An overview of recent treatment trials of brucellosis indicates that regimens combining streptomycin and doxycycline are associated with a higher success rate (judged by the frequency of treatment failure and relapse following therapy) than combinations of rifampicin and doxycycline.