0709 203000 - Nairobi 0709 983000 - Kilifi
0709 203000 - NRB 0709 983000 - Kilifi
0709 203000 - NRB | 0709 983000 - Kilifi

Abstract

The aetiologies, mortality, and disability of non-traumatic coma in African children: a systematic review and meta-analysis

Ray STJ Fuller CE Boubour A Tshimangani T Kafoteka E Muiruri-Liomba A Malenga A Tebulo A Pensulo P Gushu MB Nielsen M Raees M Stockdale E Langton J Birbeck GL Waithira N Bonnett LJ Henrion MY Fink EL Postels DG O'Brien N Page AL Baron E Gordon SB Molyneux E Dondorp A George EC Maitland K Michael BD Solomon T Chimalizeni Y Lalloo DG Moxon CA Taylor T Mallewa M Idro R Seydel K Griffiths MJ
Lancet Glob Health. 2025;13e1043-e1056

Permenent descriptor
https://doi.org/10.1016/S2214-109X(25)00055-5


BACKGROUND: Non-traumatic coma in African children is a common life-threatening presentation often leading to hospital attendance. We aimed to estimate the distribution of non-traumatic coma causes and outcomes, including disease-specific outcomes, for which evidence is scarce. METHODS: We systematically reviewed MEDLINE, Embase, and Scopus databases from inception to Feb 6, 2024. We included studies recruiting children (aged 1 month to 16 years) with non-traumatic coma (Blantyre Coma Scale score