Choice of fluids for resuscitation in children with severe infection and shock: systematic review

Akech S, Ledermann H, Maitland K
BMJ. 2010;341

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OBJECTIVE: To systemically review the evidence from clinical trials comparing the use of crystalloids and colloids for fluid resuscitation in children with severe infection. DATA SOURCES: Medline (1950-2008), PubMed, the Cochrane Library, Embase (1980-2008), and reference lists. Eligibility criteria Published studies comparing fluid resuscitation with crystalloid or colloidal solutions in severe infectious illness in children aged >1 month to