0709 203000 - Nairobi 0709 983000 - Kilifi
0709 203000 - NRB 0709 983000 - Kilifi
0709 203000 - NRB | 0709 983000 - Kilifi

Abstract

Epidemiological studies of the non-specific effects of vaccines: II--methodological issues in the design and analysis of cohort studies

Farrington CP, Firth MJ, Moulton LH, Ravn H, Andersen PK, Evans S
Trop Med Int Health. 2009;14977-85

Permenent descriptor
https://doi.org/10.1111/j.1365-3156.2009.02302.x


We review sources of bias which can affect non-randomized cohort studies of non-specific effects of vaccines on child mortality. Using examples from the literature on non-specific effects, we describe different sources of selection and information bias, and, where possible, outline analysis strategies to mitigate or eliminate such biases.