Mainga Hamaluba/Wellcome Open Res

Pf8: an open dataset of Plasmodium falciparum genome variation in 33,325 worldwide samples.Malaria Genomic Epidemiology Network Abdel Hamid MM Abdelraheem MH Acheampong DO Adam I Aide P Ajibaye O Ali M Almagro-Garcia J Amambua-Ngwa A Amenga-Etego L Aniebo I Aninagyei E Ansah F Apinjoh TO Ariani CV Auburn S Awandare GA Balmer A Bejon P Boene S Bwire G Candrinho B Chidimatembue A Chindavongsa K Comiche K Conway D Dara A Diakite M Djimde A Dondorp A Doumbia S Drury E Fanello CA Ferdig M Figueroa K Gamboa D Golassa L Goncalves S Guindo MDA Hamaluba M Hanboonkunupakarn B Howe K Hussien M Imwong M Ishengoma D Jeans J Kabaghe A Kamuhabwa A Kindermans JM Konate DS Kwiatkowski DP Lee C Lee SK Lee SJ Ley B Llanos-Cuentas A Marfurt J Matambisso G Maude RR Maude RJ Mayor A Mayxay M Maiga-Ascofare O McCann RS Miles A Miotto O Mohamed AO Morang'a CM Murie K Ngasala BE Nguyen TN Nolasco O Nosten F Noviyanti R O'Connor I Oboh M Ochola-Oyier LI Olufunke Falade C Olukosi A Olumide A Olusola FI Onyamboko MA Oriero EC Oyibo WA Pannebaker D Pearson RD Phiri K van der Pluijm RW Price RN Quang HH Rajkumar Devaraju V Randrianarivelojosia M Ranford-Cartwright L Rayner JC Rovira-Vallbona E Rowlands K Ruano-Rubio V Sanchez JF Saute F Shettima S da Silva C Simpson VJ Suddaby S Takken W Thu AM Toure M Unlu E Valdivia HO van Vugt M Waithira N Wellems T Wendler J White N Wuendrich Ogidan R
Wellcome Open Res, (2025). 10:325

A pragmatic randomized controlled trial of standard care versus corticosteroids plus standard care for treatment of pneumonia in adults admitted to Kenyan hospitals (SONIA).Lucinde R Abdi A Orindi B Mwakio S Gathuri H Onyango E Chira S Ogero M Isaaka L Shangala J Oginga IN Wachira A Manuthu E Kariuki H Nyikuli J Wekesa C Otedo A Bosire H Okoth SB Ongalo W Mukabi D Lusamba W Muthui B Kirui N Adembesa I Mithi C Sood M Ahmed N Gituma B Ongaki VB Giabe M Omondi C Ombajo LA Kagucia W English M Hamaluba M Ochola-Oyier LI Kamuya D Bejon P Agweyu A Akech S Etyang AO
Wellcome Open Res, (2025). 7:269

SEVUparin as a potential Adjunctive Treatment in children with severe malaria: A phase I trial safety and dose finding trial (SEVUSMAART).Maitland K Hamaluba M Obonyo N Oguda E Mogoka C Williams TN Chaponda M Miti S Kamavu LK Jonathan Gwasupika J Connon R Gibb DM Dondorp A Day N White N Walker AS George EC Severe Malaria in African Children AResearch Trials consortium
Wellcome Open Res, (2024). 8:484

A Phase I trial of Non-invasive Ventilation and seizure prophylaxis with levetiracetam In Children with Cerebral Malaria Trial (NOVICE-M Trial).Maitland K Obonyo N Hamaluba M Ogoda E Mogaka C Williams TN Newton C Kariuki SM Gibb DM Walker AS Connon R George EC
Wellcome Open Res, (2024). 9:281

Targeted amplicon deep sequencing of ama1 and mdr1 to track within-host P. falciparum diversity throughout treatment in a clinical drug trial.Wamae K Ndwiga L Kharabora O Kimenyi K Osoti V de Laurent Z Wambua J Musyoki J Ngetsa C Kalume P Mwambingu G Hamaluba M van der Pluijm R Dondorp AM Bailey J Juliano J Bejon P Ochola-Oyier L
Wellcome Open Res, (2024). 7:95

Gastroenteritis Rehydration Of children with Severe Acute Malnutrition (GASTROSAM): A Phase II Randomised Controlled trial: Trial Protocol.Olupot-Olupot P Aloroker F Mpoya A Mnjalla H Paasi G Nakuya M Houston K Obonyo N Hamaluba M Evans JA Dewez M Atti S Guindo O Ouattara SM Chara A Sainna HA Amos OO Ogundipe O Sunyoto T Coldiron M Langendorf C Scherrer MF Petrucci R Connon R George EC Gibb DM Maitland K
Wellcome Open Res, (2024). 6:160

Safety and immunogenicity of varied doses of R21/Matrix-M vaccine at three years follow-up: A phase 1b age de-escalation, dose-escalation trial in adults, children, and infants in Kilifi-Kenya.Sang S Datoo MS Otieno E Muiruri C Bellamy D Gathuri E Ngoto O Musembi J Provstgaard-Morys S Stockdale L Aboagye J Woods D Lawrie A Roberts R Keter K Kimani D Ndungu F Kapulu M Njau I Orindi B Ewer KJ Hill AVS Bejon P Hamaluba M
Wellcome Open Res, (2023). 8:450

Safety and immunogenicity of ChAdOx1 nCoV-19 (AZD1222) vaccine in adults in Kenya: a phase 1/2 single-blind, randomised controlled trial.Hamaluba M Sang S Orindi B Njau I Karanja H Kamau N Gitonga JN Mugo D Wright D Nyagwange J Kutima B Omuoyo D Mwatasa M Ngetsa C Agoti C Cheruiyot S Nyaguara A Munene M Mturi N Oloo E Ochola-Oyier L Mumba N Mauncho C Namayi R Davies A Tsofa B Nduati EW Aliyan N Kasera K Etyang A Boyd A Hill A Gilbert S Douglas A Pollard A Bejon P Lambe T Warimwe G COVVaccine Trial Group
Wellcome Open Res, (2023). 8:182

TRUE-1: Trial of Repurposed Unithiol for snakebite Envenoming phase 1 (safety, tolerability, pharmacokinetics and pharmacodynamics in healthy Kenyan adults).Abouyannis M FitzGerald R Ngama M Mwangudzah H Nyambura YK Ngome S Riako D Babu L Lewa F Else L Dily Penchala S Orindi B Mumba N Kalama B Ndungu FM Adetifa I Khoo S Lalloo DG Casewell NR Hamaluba M
Wellcome Open Res, (2022). 7:90

Children's Oxygen Administration Strategies And Nutrition Trial (COAST-Nutrition): a protocol for a phase II randomised controlled trial.Kiguli S Olopot-Olupot P Alaroker F Engoru C Opoka RO Tagoola A Hamaluba M Mnjalla H Mpoya A Mogaka C Nalwanga D Nabawanuka E Nokes J Nyaigoti C Briend A van Woensel JBM Grieve R Sadique Z Williams TN Thomas K Harrison DA Rowan K Maitland K
Wellcome Open Res, (2021). 6:221