Tom Williams

Immediate Transfusion in African Children with Uncomplicated Severe Anemia.Maitland K Kiguli S Olupot-Olupot P Engoru C Mallewa M Saramago Goncalves P Opoka RO Mpoya A Alaroker F Nteziyaremye J Chagaluka G Kennedy N Nabawanuka E Nakuya M Namayanja C Uyoga S Kyeyune Byabazaire D M'Baya B Wabwire B Frost G Bates I Evans JA Williams TN George EC Gibb DM Walker AS Tract Group
N Engl J Med, (2019). 381:407-419

Observational study: 27 years of severe malaria surveillance in Kilifi, Kenya.Njuguna P Maitland K Nyaguara A Mwanga D Mogeni P Mturi N Mohammed S Mwambingu G Ngetsa C Awuondo K Lowe B Adetifa I Scott JAG Williams TN Atkinson S Osier F Snow RW Marsh K Tsofa B Peshu N Hamaluba M Berkley JA Newton CRJ Fondo J Omar A Bejon P
BMC Med, (2019). 17:124

Gametocyte carriage in an era of changing malaria epidemiology: A 19-year analysis of a malaria longitudinal cohort.Muthui MK Mogeni P Mwai K Nyundo C Macharia A Williams TN Nyangweso G Wambua J Mwanga D Marsh K Bejon P Kapulu MC
Wellcome Open Res, (2019). 4:66

Effect of strikes by health workers on mortality between 2010 and 2016 in Kilifi, Kenya: a population-based cohort analysis.Ong'ayo G Ooko M Wang'ondu R Bottomley C Nyaguara A Tsofa BK Williams TN Bejon P Scott JAG Etyang AO
Lancet Glob Health, (2019). 7:e961-e967

Effect of ten-valent pneumococcal conjugate vaccine on invasive pneumococcal disease and nasopharyngeal carriage in Kenya: a longitudinal surveillance study.Hammitt LL Etyang AO Morpeth SC Ojal J Mutuku A Mturi N Moisi JC Adetifa IM Karani A Akech DO Otiende M Bwanaali T Wafula J Mataza C Mumbo E Tabu C Knoll MD Bauni E Marsh K Williams TN Kamau T Sharif SK Levine OS Scott JAG
Lancet, (2019). 393:2146-2154

Effect of Previous Exposure to Malaria on Blood Pressure in Kilifi, Kenya: A Mendelian Randomization Study.Etyang AO Kapesa S Odipo E Bauni E Kyobutungi C Abdalla M Muntner P Musani SK Macharia A Williams TN Cruickshank JK Smeeth L Scott JAG
J Am Heart Assoc, (2019). 8:e011771

Haematological quality and age of donor blood issued for paediatric transfusion to four hospitals in sub-Saharan Africa.Uyoga S Mpoya A Olupot-Olupot P Kiguli S Opoka RO Engoru C Mallewa M Kennedy N M'Baya B Kyeyune D Wabwire B Bates I Gibb DM Walker AS George EC Williams TN Maitland K
Vox Sang, (2019). 114:340-348

The indirect health effects of malaria estimated from health advantages of the sickle cell trait.Uyoga S Macharia AW Ndila CM Nyutu G Shebe M Awuondo KO Mturi N Peshu N Tsofa B Scott JAG Maitland K Williams TN
Nat Commun, (2019). 10:856

Effect of 10-valent pneumococcal conjugate vaccine on the incidence of radiologically-confirmed pneumonia and clinically-defined pneumonia in Kenyan children: an interrupted time-series analysis.Silaba M Ooko M Bottomley C Sande J Benamore R Park K Ignas J Maitland K Mturi N Makumi A Otiende M Kagwanja S Safari S Ochola V Bwanaali T Bauni E Gleeson F Deloria Knoll M Adetifa I Marsh K Williams TN Kamau T Sharif S Levine OS Hammitt LL Scott JAG
Lancet Glob Health, (2019). 7:e337-e346

Hydroxyurea for Children with Sickle Cell Anemia in Sub-Saharan Africa.Tshilolo L Tomlinson G Williams TN Santos B Olupot-Olupot P Lane A Aygun B Stuber SE Latham TS McGann PT Ware RE Reach Investigators
N Engl J Med, (2019). 380:121-131

The population dynamics of hemoglobins A, A(2), F and S in the context of the hemoglobinopathies HbS and alpha-thalassemia in Kenyan infants.Macharia AW Uyoga S Ndila C Nyutu G Makale J Tendwa M Nyatichi E Ojal J Atkinson S Williams TN
Haematologica, (2019). 104:e184-e186

Iron Status and Associated Malaria Risk Among African Children.Muriuki JM Mentzer AJ Kimita W Ndungu FM Macharia AW Webb EL Lule SA Morovat A Hill AVS Bejon P Elliott AM Williams TN Atkinson SH
Clin Infect Dis, (2019). 68:1807-1814

Evaluation of the diagnostic accuracy and cost of different methods for the assessment of severe anaemia in hospitalised children in Eastern Uganda.Olupot-Olupot P Prevatt N Engoru C Nteziyaremye J Amorut D Chebet M Senyondo T Ongodia P Ndila CM Williams TN Maitland K
Wellcome Open Res, (2018). 3:130

Sickle Cell and alpha+-Thalassemia Traits Influence the Association between Ferritin and Hepcidin in Rural Kenyan Children Aged 14-26 Months.Byrd KA Williams TN Lin A Pickering AJ Arnold BF Arnold CD Kiprotich M Dentz HN Njenga SM Rao G Colford JM, Jr Null C Stewart CP
J Nutr, (2018). 148:1903-1910

Coverage and timeliness of vaccination and the validity of routine estimates: Insights from a vaccine registry in Kenya.Adetifa IMO Karia B Mutuku A Bwanaali T Makumi A Wafula J Chome M Mwatsuma P Bauni E Hammitt LL Mataza C Tabu C Kamau T Williams TN Scott JAG
Vaccine, (2018). 36:7965-7974

Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study.Ndila CM Uyoga S Macharia AW Nyutu G Peshu N Ojal J Shebe M Awuondo KO Mturi N Tsofa B Sepulveda N Clark TG Band G Clarke G Rowlands K Hubbart C Jeffreys A Kariuki S Marsh K Mackinnon M Maitland K Kwiatkowski DP Rockett KA Williams TN Malaria GENConsortium
Lancet Haematol, (2018). 5:e333-e345

Two complement receptor one alleles have opposing associations with cerebral malaria and interact with alpha(+)thalassaemia.Opi DH Swann O Macharia A Uyoga S Band G Ndila CM Harrison EM Thera MA Kone AK Diallo DA Doumbo OK Lyke KE Plowe CV Moulds JM Shebbe M Mturi N Peshu N Maitland K Raza A Kwiatkowski DP Rockett KA Williams TN Rowe JA
Elife, (2018). 7:

Sickle Cell Anemia and Its Phenotypes.Williams TN Thein SL
Annu Rev Genomics Hum Genet, (2018). 19:113-147

Genetic variation in VAC14 is associated with bacteremia secondary to diverse pathogens in African children.Gilchrist JJ Mentzer AJ Rautanen A Pirinen M Mwarumba S Njuguna P Mturi N Wellcome Trust Case-Control Consortium Kenyan Bacteraemia Study Group Williams TN Scott JAG Hill AVS
Proc Natl Acad Sci U S A, (2018). 115:E3601-E3603

Risk of nontyphoidal Salmonella bacteraemia in African children is modified by STAT4.Gilchrist JJ Rautanen A Fairfax BP Mills TC Naranbhai V Trochet H Pirinen M Muthumbi E Mwarumba S Njuguna P Mturi N Msefula CL Gondwe EN MacLennan JM Chapman SJ Molyneux ME Knight JC Spencer CCA Williams TN MacLennan CA Scott JAG Hill AVS
Nat Commun, (2018). 9:1014