Abstract

Genotypes of multidrug-resistant Salmonella enterica serotype typhimurium from two regions of Kenya

Kariuki, S. Oundo, J. O. Muyodi, J. Lowe, B. Threlfall, E. J. Hart, C. A.
FEMS Immunol Med Microbiol. 2000; 299-13

Permanent descriptor

https://doi.org/10.1111/j.1574-695X.2000.tb01498.x

A combination of phage typing and pulsed-field gel electrophoresis of Xbal-digested chromosomal DNA has been used to study the epidemiological relationships of multidrug-resistant Salmonella enterica serotype typhimurium from Nairobi (64 isolates) and Kilifi (40 isolates) collected over the period 1994-1997. Isolates from Nairobi belonged to 11 definitive phage types (DTs) encompassing eight different PFGE patterns. In contrast, isolates from Kilifi were mainly DT 56 (60%) and all fell into a single PFGE pattern. The remaining isolates did not conform to a recognisable phage type. We conclude that multidrug-resistant S. typhimurium infections from Nairobi were caused by multiple strains while those from Kilifi were likely to be from a microepidemic caused by a single clone.