Abstract

Capsular Typing Method for Streptococcus agalactiae Using Whole-Genome Sequence Data

Sheppard AE, Vaughan A, Jones N, Turner P, Turner C, Efstratiou A, Patel D, Modernising Medical Microbiology Informatics Group, Walker AS, Berkley JA, Crook DW, Seale AC
J Clin Microbiol. 2016;54

Permenent descriptor
https://doi.org/10.1128/JCM.03142-15


Group B streptococcus (GBS) capsular serotypes are major determinants of virulence and affect potential vaccine coverage. Here we report a whole-genome-sequencing-based method for GBS serotype assignment. This method shows strong agreement (kappa of 0.92) with conventional methods and increased serotype assignment (100%) to all 10 capsular types.