Isabella Ochola-Oyier/Antimicrob Agents Chemother

A retrospective analysis of P. falciparum drug resistance markers detects an early (2016/17) high prevalence of the k13 C469Y mutation in asymptomatic infections in Northern Uganda.Ogwang R Osoti V Wamae K Ndwiga L Muteru K Ningwa A Tuju J Kinyanjui S Osier F Marsh K Bejon P Idro R Ochola-Oyier LI
Antimicrob Agents Chemother, (2024). 68:e0157623

Targeted Amplicon Deep Sequencing for Monitoring Antimalarial Resistance Markers in Western Kenya.Osoti V Akinyi M Wamae K Kimenyi KM de Laurent Z Ndwiga L Gichuki P Okoyo C Kepha S Mwandawiro C Kandie R Bejon P Snow RW Ochola-Oyier LI
Antimicrob Agents Chemother, (2022). 66:e0194521

No evidence of P. falciparum K13 artemisinin conferring mutations over a 24-year analysis in Coastal Kenya, but a near complete reversion to chloroquine wild type parasites.Wamae K Okanda D Ndwiga L Osoti V Kimenyi KM Abdi AI Bejon P Sutherland C Ochola-Oyier LI
Antimicrob Agents Chemother, (2019). 63:

The MSPDBL2 codon 591 polymorphism is associated with lumefantrine in vitro drug responses in Plasmodium falciparum isolates from Kilifi, Kenya.Ochola-Oyier LI Okombo J Mwai L Kiara SM Pole L Tetteh KK Nzila A Marsh K
Antimicrob Agents Chemother, (2015). 59:1770-5

Repeat polymorphisms in the low-complexity regions of Plasmodium falciparum ABC transporters and associations with in vitro antimalarial responses.Okombo J Abdi AI Kiara SM Mwai L Pole L Sutherland CJ Nzila A Ochola-Oyier LI
Antimicrob Agents Chemother, (2013). 57:6196-204

The polymorphic linker domain of pfmdr1 is associated with resistance-conferring mutations in Plasmodium falciparum populations from East and West Africa.Okombo J Zongo I Gadalla N Bousema T Beshir KB Roper C Hallett R Ochola-Oyier LI Sutherland CJ
Antimicrob Agents Chemother, (2013). 57:4595-8