Biosciences
Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study.Ndila CM, Uyoga S, Macharia AW, Nyutu G, Peshu N, Ojal J, Shebe M, Awuondo KO, Mturi N, Tsofa B, Sepulveda N, Clark TG, Band G, Clarke G, Rowlands K, Hubbart C, Jeffreys A, Kariuki S, Marsh K, Mackinnon M, Maitland K, Kwiatkowski DP, Rockett KA, Williams TN, Malaria GENConsortium
Lancet Haematol, (2018). 5:e333-e345
Pathway to Deployment of Gene Drive Mosquitoes as a Potential Biocontrol Tool for Elimination of Malaria in Sub-Saharan Africa: Recommendations of a Scientific Working Group(dagger).James S, Collins FH, Welkhoff PA, Emerson C, Godfray HCJ, Gottlieb M, Greenwood B, Lindsay SW, Mbogo CM, Okumu FO, Quemada H, Savadogo M, Singh JA, Tountas KH, Toure YT
Am J Trop Med Hyg, (2018). 98:1-49
Long read assemblies of geographically dispersed Plasmodium falciparum isolates reveal highly structured subtelomeres.Otto TD, Bohme U, Sanders M, Reid A, Bruske EI, Duffy CW, Bull PC, Pearson RD, Abdi A, Dimonte S, Stewart LB, Campino S, Kekre M, Hamilton WL, Claessens A, Volkman SK, Ndiaye D, Amambua-Ngwa A, Diakite M, Fairhurst RM, Conway DJ, Franck M, Newbold CI, Berriman M
Wellcome Open Res, (2018). 3:52
Ethical considerations in Controlled Human Malaria Infection studies in low resource settings: Experiences and perceptions of study participants in a malaria Challenge study in Kenya.Njue M, Njuguna P, Kapulu MC, Sanga G, Bejon P, Marsh V, Molyneux S, Kamuya D
Wellcome Open Res, (2018). 3:39
Gene copy number variation in natural populations of Plasmodium falciparum in Eastern Africa.Simam J, Rono M, Ngoi J, Nyonda M, Mok S, Marsh K, Bozdech Z, Mackinnon M
BMC Genomics, (2018). 19:372
Determinants of antibody persistence across doses and continents after single-dose rVSV-ZEBOV vaccination for Ebola virus disease: an observational cohort study.Huttner A, Agnandji ST, Combescure C, Fernandes JF, Bache EB, Kabwende L, Ndungu FM, Brosnahan J, Monath TP, Lemaitre B, Grillet S, Botto M, Engler O, Portmann J, Siegrist D, Bejon P, Silvera P, Kremsner P, Siegrist CA, VEBCON, VSV-EBOVAC, VSV-EBOPLUS Consortia
Lancet Infect Dis, (2018). 18:738-748
Human Immunization With a Polymorphic Malaria Vaccine Candidate Induced Antibodies to Conserved Epitopes That Promote Functional Antibodies to Multiple Parasite Strains.Feng G, Boyle MJ, Cross N, Chan JA, Reiling L, Osier F, Stanisic DI, Mueller I, Anders RF, McCarthy JS, Richards JS, Beeson JG
J Infect Dis, (2018). 218:35-43
Polymorphisms in the K13 Gene in Plasmodium falciparum from Different Malaria Transmission Areas of Kenya.de Laurent ZR, Chebon LJ, Ingasia LA, Akala HM, Andagalu B, Ochola-Oyier LI, Kamau E
Am J Trop Med Hyg, (2018). 98:1360-1366
Mosquito repellents for malaria prevention.Maia MF, Kliner M, Richardson M, Lengeler C, Moore SJ
Cochrane Database Syst Rev, (2018). 2:CD011595
Single low-dose primaquine for blocking transmission of Plasmodium falciparum malaria - a proposed model-derived age-based regimen for sub-Saharan Africa.Taylor WR, Naw HK, Maitland K, Williams TN, Kapulu M, D'Alessandro U, Berkley JA, Bejon P, Okebe J, Achan J, Amambua AN, Affara M, Nwakanma D, van Geertruyden JP, Mavoko M, Lutumba P, Matangila J, Brasseur P, Piola P, Randremanana R, Lasry E, Fanello C, Onyamboko M, Schramm B, Yah Z, Jones J, Fairhurst RM, Diakite M, Malenga G, Molyneux M, Rwagacondo C, Obonyo C, Gadisa E, Aseffa A, Loolpapit M, Henry MC, Dorsey G, John C, Sirima SB, Barnes KI, Kremsner P, Day NP, White NJ, Mukaka M
BMC Med, (2018). 16:11
Attractive toxic sugar baits for controlling mosquitoes: a qualitative study in Bagamoyo, Tanzania.Maia MF, Tenywa FC, Nelson H, Kambagha A, Ashura A, Bakari I, Mruah D, Simba A, Bedford A
Malar J, (2018). 17:22
Adaptation of Plasmodium falciparum to its transmission environment.Rono MK, Nyonda MA, Simam JJ, Ngoi JM, Mok S, Kortok MM, Abdullah AS, Elfaki MM, Waitumbi JN, El-Hassan IM, Marsh K, Bozdech Z, Mackinnon MJ
Nat Ecol Evol, (2018). 2:377-387
Variation in the effectiveness of insecticide treated nets against malaria and outdoor biting by vectors in Kilifi, Kenya.Kamau A, Mwangangi JM, Rono MK, Mogeni P, Omedo I, Midega J, Scott JAG, Bejon P
Wellcome Open Res, (2017). 2:22
Amodiaquine resistance in Plasmodium berghei is associated with PbCRT His95Pro mutation, loss of chloroquine, artemisinin and primaquine sensitivity, and high transcript levels of key transporters.Ndung'u L, Langat B, Magiri E, Ng'ang'a J, Irungu B, Nzila A, Kiboi D
Wellcome Open Res, (2017). 2:44
Prevalence, causes, and behavioral and emotional comorbidities of acute symptomatic seizures in Africa: A critical review.Kariuki SM, Abubakar A, Stein A, Marsh K, Newton CRJC
Epilepsia Open, (2017). 2:8-19
A Phase 2a Randomized Study to Evaluate the Safety and Immunogenicity of the 1790GAHB Generalized Modules for Membrane Antigen Vaccine against Shigella sonnei Administered Intramuscularly to Adults from a Shigellosis-Endemic Country.Obiero CW, Ndiaye AGW, Scire AS, Kaunyangi BM, Marchetti E, Gone AM, Schutte LD, Riccucci D, Auerbach J, Saul A, Martin LB, Bejon P, Njuguna P, Podda A
Front Immunol, (2017). 8:1884
Trends in bednet ownership and usage, and the effect of bednets on malaria hospitalization in the Kilifi Health and Demographic Surveillance System (KHDSS): 2008-2015.Kamau A, Nyaga V, Bauni E, Tsofa B, Noor AM, Bejon P, Scott JAG, Hammitt LL
BMC Infect Dis, (2017). 17:720
Examining the human infectious reservoir for Plasmodium falciparum malaria in areas of differing transmission intensity.Goncalves BP, Kapulu MC, Sawa P, Guelbeogo WM, Tiono AB, Grignard L, Stone W, Hellewell J, Lanke K, Bastiaens GJH, Bradley J, Nebie I, Ngoi JM, Oriango R, Mkabili D, Nyaurah M, Midega J, Wirth DF, Marsh K, Churcher TS, Bejon P, Sirima SB, Drakeley C, Bousema T
Nat Commun, (2017). 8:1133
The prevalence of Plasmodium falciparum in sub-Saharan Africa since 1900.Snow RW, Sartorius B, Kyalo D, Maina J, Amratia P, Mundia CW, Bejon P, Noor AM
Nature, (2017). 550:515-518
A framework for Controlled Human Infection Model (CHIM) studies in Malawi: Report of a Wellcome Trust workshop on CHIM in Low Income Countries held in Blantyre, Malawi.Gordon SB, Rylance J, Luck A, Jambo K, Ferreira DM, Manda-Taylor L, Bejon P, Ngwira B, Littler K, Seager Z, Gibani M, Gmeiner M, Roestenberg M, Mlombe Y, Wellcome Trust CHIM workshop participants
Wellcome Open Res, (2017). 2:70