Wellcome Open Res

An optimization of four SARS-CoV-2 qRT-PCR assays in a Kenyan laboratory to support the national COVID-19 rapid response teams.Mohammed, K. S. de Laurent, Z. R. Omuoyo, D. O. Lewa, C. Gicheru, E. Cheruiyot, R. Bartilol, B. Mutua, S. Musyoki, J. Gumba, H. Mwacharo, J. Riako, D. Mwangi, S. J. Gichuki, B. M. Nyamako, L. Karani, A. Karanja, H. Mugo, D. Gitonga, J. N. Njuguna, S. Gumbi, W. Tawa, B. Tendwa, M. Cheruiyot, W. Sein, Y. Nyambu, J. K. Patta, S. O. Thani, T. S. Maitha, E. K. Kitole, B. Mwakinangu, M. S. Muslih, B. S. Otieno, J. O. Nyiro, J. U. Kiyuka, P. Ndwiga, L. Wamae, K. Kimani, D. Makale, J. Morobe, J. M. Osoti, V. Lambisia, A. W. Odundo, C. Mwarumba, S. Mutunga, M. Bejon, P. Tsofa, B. Agoti, C. N. Ochola-Oyier, L. I.
Wellcome Open Res, (2020). 5:162

Haplotype heterogeneity and low linkage disequilibrium reduce reliable prediction of genotypes for the ‑alpha (3.7I) form of alpha-thalassaemia using genome-wide microarray data.Ndila, C. M. Nyirongo, V. Macharia, A. W. Jeffreys, A. E. Rowlands, K. Hubbart, C. Busby, G. B. J. Band, G. Harding, R. M. Rockett, K. A. Williams, T. N. Malaria, G. E. N. Consortium
Wellcome Open Res, (2020). 5:287

Addressing diversity and complexity in the community engagement literature: The rationale for a realist review.Richardson, E. Z. L. Bandewar, S. V. S. Boulanger, R. F. Mehta, R. Lin, T. Vincent, R. Molyneux, S. Goldstone, A. Lavery, J. V.
Wellcome Open Res, (2020). 5:1

Systemic inflammation is negatively associated with early post discharge growth following acute illness among severely malnourished children - a pilot study.Njunge, J. M. Gonzales, G. B. Ngari, M. M. Thitiri, J. Bandsma, R. H. J. Berkley, J. A.
Wellcome Open Res, (2020). 5:248

A reproducible picture of open access health facility data in Africa and R tools to support improvement.South, A. Dicko, A. Herringer, M. Macharia, P. M. Maina, J. Okiro, E. A. Snow, R. W. van der Walt, A.
Wellcome Open Res, (2020). 5:157

Plasma calprotectin as a biomarker of mortality at antiretroviral treatment initiation in advanced HIV - pilot study.Kamau, F. W. Gwela, A. Nyerere, A. K. Riitho, V. Njunge, J. M. Ngari, M. M. Prendergast, A. J. Berkley, J. A.
Wellcome Open Res, (2020). 5:46

Programme theory and linked intervention strategy for large-scale change to improve hospital care in a low and middle-income country - A Study Pre-Protocol.English, M. Nzinga, J. Irimu, G. Gathara, D. Aluvaala, J. McKnight, J. Wong, G. Molyneux, S.
Wellcome Open Res, (2020). 5:265

Effectiveness of Rotarix ((R)) vaccine in Africa in the first decade of progressive introduction, 2009-2019: systematic review and meta-analysis.Murunga, N. Otieno, G. P. Maia, M. Agoti, C. N.
Wellcome Open Res, (2020). 5:187

Infection prevention and control during the COVID-19 pandemic: challenges and opportunities for Kenyan public hospitals.Maina, M. Tosas-Auguet, O. English, M. Schultsz, C. McKnight, J.
Wellcome Open Res, (2020). 5:211

Mortality during and following hospital admission among school-aged children: a cohort study.Ngari, M. M. Obiero, C. Mwangome, M. K. Nyaguara, A. Mturi, N. Murunga, S. Otiende, M. Iversen, P. O. Fegan, G. W. Walson, J. L. Berkley, J. A.
Wellcome Open Res, (2020). 5:234

Pooled testing conserves SARS-CoV-2 laboratory resources and improves test turn-around time: experience on the Kenyan Coast.Agoti, C. N. Mutunga, M. Lambisia, A. W. Kimani, D. Cheruiyot, R. Kiyuka, P. Lewa, C. Gicheru, E. Tendwa, M. Said Mohammed, K. Osoti, V. Makale, J. Tawa, B. Odundo, C. Cheruiyot, W. Nyamu, W. Gumbi, W. Mwacharo, J. Nyamako, L. Otieno, E. Amadi, D. Thoya, J. Karani, A. Mugo, D. Musyoki, J. Gumba, H. Mwarumba, S. M. Gichuki B Njuguna, S. Riako, D. Mutua, S. Gitonga, J. N. Sein, Y. Bartilol, B. Mwangi, S. J. O. Omuoyo D M. Morobe J de Laurent, Z. R. Bejon, P. Ochola-Oyier, L. I. Tsofa, B.
Wellcome Open Res, (2020). 5:186

Surveillance of respiratory viruses among children attending a primary school in rural coastal Kenya.Adema, I. W. Kamau, E. Uchi Nyiro, J. Otieno, G. P. Lewa, C. Munywoki, P. K. Nokes, D. J.
Wellcome Open Res, (2020). 5:63

Cost and cost-effectiveness analysis of treatment for child undernutrition in low- and middle-income countries: A systematic review.Njuguna, R. G. Berkley, J. A. Jemutai, J.
Wellcome Open Res, (2020). 5:62

Surveillance of endemic human coronaviruses (HCoV-NL63, OC43 and 229E) associated with childhood pneumonia in Kilifi, Kenya.Otieno, G. P. Murunga, N. Agoti, C. N. Gallagher, K. E. Awori, J. O. Nokes, D. J.
Wellcome Open Res, (2020). 5:150

Accuracy of diagnostic tests for respiratory syncytial virus infection within a paediatric hospital population in Kilifi County, Kenya.Mweu, M. M. Murunga, N. Otieno, J. W. Nokes, D. J.
Wellcome Open Res, (2020). 5:155

Characterising demographics, knowledge, practices and clinical care among patients attending sickle cell disease clinics in Eastern Uganda.Olupot-Olupot, P. Wabwire, H. Ndila, C. Adong, R. Ochen, L. Amorut, D. Abongo, G. Okalebo, C. B. Akello, S. R. Oketcho, J. B. Okiror, W. Asio, S. Odiit, A. Alaroker, F. Nyutu, G. Maitland, K. Williams, T. N.
Wellcome Open Res, (2020). 5:87

Methodological rigor of prognostic models for predicting in-hospital paediatric mortality in low- and middle-income countries: a systematic review protocol.Ogero, M. Sarguta, R. Malla, L. Aluvaala, J. Agweyu, A. Akech, S.
Wellcome Open Res, (2020). 5:106

Interferon-gamma polymorphisms and risk of iron deficiency and anaemia in Gambian children.Abuga, K. M. Rockett, K. A. Muriuki, J. M. Koch, O. Nairz, M. Sirugo, G. Bejon, P. Kwiatkowski, D. P. Prentice, A. M. Atkinson, S. H.
Wellcome Open Res, (2020). 5:40

Effects of vitamin D deficiency on neurobehavioural outcomes in children: a systematic review.Mutua, A. M. Mogire, R. M. Elliott, A. M. Williams, T. N. Webb, E. L. Abubakar, A. Atkinson, S. H.
Wellcome Open Res, (2020). 5:28

Derivation and internal validation of a data-driven prediction model to guide frontline health workers in triaging children under-five in Nairobi, Kenya.Mawji, A. Akech, S. Mwaniki, P. Dunsmuir, D. Bone, J. Wiens, M. O. Gorges, M. Kimutai, D. Kissoon, N. English, M. Ansermino, M. J.
Wellcome Open Res, (2019). 4:121