Publications

Biosciences

Estimation of the sequestered parasite load in severe malaria patients using both host and parasite markers.Ochola, L. B. Marsh, K. Lowe, B. Gal, S. Pluschke, G. Smith, T.
Parasitology, (2005). 131:449-58

2,4-diaminopteridine-based compounds as precursors for de novo synthesis of antifolates: a novel class of antimalarials.Nduati, E. Hunt, S. Kamau, E. M. Nzila, A.
Antimicrob Agents Chemother, (2005). 49:3652-7

Plasmodium falciparum antigenic variation: relationships between in vivo selection, acquired antibody response, and disease severity.Bull, P. C. Pain, A. Ndungu, F. M. Kinyanjui, S. M. Roberts, D. J. Newbold, C. I. Marsh, K.
J Infect Dis, (2005). 192:1119-26

Trust and informed consent: insights from community members on the Kenyan coast.Molyneux, C. S. Peshu, N. Marsh, K.
Soc Sci Med, (2005). 61:1463-73

Progressive increase in antimicrobial resistance among invasive isolates of Haemophilus influenzae obtained from children admitted to a hospital in Kilifi, Kenya, from 1994 to 2002.Scott, J. A. Mwarumba, S. Ngetsa, C. Njenga, S. Lowe, B. S. Slack, M. P. Berkley, J. A. Mwangi, I. Maitland, K. English, M. Marsh, K.
Antimicrob Agents Chemother, (2005). 49:3021-4

Sickle cell trait and the risk of Plasmodium falciparum malaria and other childhood diseases.Williams, T. N. Mwangi, T. W. Wambua, S. Alexander, N. D. Kortok, M. Snow, R. W. Marsh, K.
J Infect Dis, (2005). 192:178-86

Clinical algorithms for malaria diagnosis lack utility among people of different age groups.Mwangi, T. W. Mohammed, M. Dayo, H. Snow, R. W. Marsh, K.
Trop Med Int Health, (2005). 10:530-6

Comparative folate metabolism in humans and malaria parasites (part II): activities as yet untargeted or specific to Plasmodium.Nzila, A. Ward, S. A. Marsh, K. Sims, P. F. Hyde, J. E.
Trends Parasitol, (2005). 21:334-9

Comparative folate metabolism in humans and malaria parasites (part I): pointers for malaria treatment from cancer chemotherapy.Nzila, A. Ward, S. A. Marsh, K. Sims, P. F. Hyde, J. E.
Trends Parasitol, (2005). 21:292-8

An immune basis for malaria protection by the sickle cell trait.Williams, T. N. Mwangi, T. W. Roberts, D. J. Alexander, N. D. Weatherall, D. J. Wambua, S. Kortok, M. Snow, R. W. Marsh, K.
PLoS Med, (2005). 2:e128

Invasive Gram-negative bacilli are frequently resistant to standard antibiotics for children admitted to hospital in Kilifi, Kenya.Bejon, P. Mwangi, I. Ngetsa, C. Mwarumba, S. Berkley, J. A. Lowe, B. S. Maitland, K. Marsh, K. English, M. Scott, J. A.
J Antimicrob Chemother, (2005). 56:232-5

'Even if they ask you to stand by a tree all day, you will have to do it (laughter)...!': community voices on the notion and practice of informed consent for biomedical research in developing countries.Molyneux, C. S. Wassenaar, D. R. Peshu, N. Marsh, K.
Soc Sci Med, (2005). 61:443-54

Case definitions of clinical malaria under different transmission conditions in Kilifi District, Kenya.Mwangi, T. W. Ross, A. Snow, R. W. Marsh, K.
J Infect Dis, (2005). 191:1932-9

Neonatal measles immunity in rural Kenya: the influence of HIV and placental malaria infections on placental transfer of antibodies and levels of antibody in maternal and cord serum samples.Scott, S. Cumberland, P. Shulman, C. E. Cousens, S. Cohen, B. J. Brown, D. W. Bulmer, J. N. Dorman, E. K. Kawuondo, K. Marsh, K. Cutts, F.
J Infect Dis, (2005). 191:1854-60

The role of sequential administration of sulphadoxine/pyrimethamine following quinine in the treatment of severe falciparum malaria in children.Ogutu, B. R. Nzila, A. M. Ochong, E. Mithwani, S. Wamola, B. Olola, C. H. Lowe, B. Kokwaro, G. O. Marsh, K. Newton, C. R.
Trop Med Int Health, (2005). 10:484-8

Cytokine mRNA expression and iron status in children living in a malaria endemic area.Nyakeriga, A. M. Williams, T. N. Marsh, K. Wambua, S. Perlmann, H. Perlmann, P. Grandien, A. Troye-Blomberg, M.
Scand J Immunol, (2005). 61:370-5

B cell memory to 3 Plasmodium falciparum blood-stage antigens in a malaria-endemic area.Dorfman, J. R. Bejon, P. Ndungu, F. M. Langhorne, J. Kortok, M. M. Lowe, B. S. Mwangi, T. W. Williams, T. N. Marsh, K.
J Infect Dis, (2005). 191:1623-30

Genomewide analysis of the host response to malaria in Kenyan children.Griffiths, M. J. Shafi, M. J. Popper, S. J. Hemingway, C. A. Kortok, M. M. Wathen, A. Rockett, K. A. Mott, R. Levin, M. Newton, C. R. Marsh, K. Relman, D. A. Kwiatkowski, D. P.
J Infect Dis, (2005). 191:1599-611

Use of clinical syndromes to target antibiotic prescribing in seriously ill children in malaria endemic area: observational study.Berkley, J. A. Maitland, K. Mwangi, I. Ngetsa, C. Mwarumba, S. Lowe, B. S. Newton, C. R. Marsh, K. Scott, J. A. English, M.
BMJ, (2005). 330:995

Why has the dihydrofolate reductase 164 mutation not consistently been found in Africa yet?.Nzila, A. Ochong, E. Nduati, E. Gilbert, K. Winstanley, P. Ward, S. Marsh, K.
Trans R Soc Trop Med Hyg, (2005). 99:341-6