Publications

Epidemiology and Demography

Effect of ready-to-use supplementary food on mortality in severely immunocompromised HIV-infected individuals in Africa initiating antiretroviral therapy (REALITY): an open-label, parallel-group, randomised controlled trial.Mallewa, J. Szubert, A. J. Mugyenyi, P. Chidziva, E. Thomason, M. J. Chepkorir, P. Abongomera, G. Baleeta, K. Etyang, A. Warambwa, C. Melly, B. Mudzingwa, S. Kelly, C. Agutu, C. Wilkes, H. Nkomani, S. Musiime, V. Lugemwa, A. Pett, S. L. Bwakura-Dangarembizi, M. Prendergast, A. J. Gibb, D. M. Walker, A. S. Berkley, J. A. Reality trial team
Lancet HIV, (2018). 5:e231-e240

Sickle Cell Anemia and Its Phenotypes.Williams, T. N. Thein, S. L.
Annu Rev Genomics Hum Genet, (2018). 19:113-147

Genetic variation in VAC14 is associated with bacteremia secondary to diverse pathogens in African children.Gilchrist, J. J. Mentzer, A. J. Rautanen, A. Pirinen, M. Mwarumba, S. Njuguna, P. Mturi, N. Wellcome Trust Case-Control, Consortium Kenyan Bacteraemia Study, Group Williams, T. N. Scott, J. A. G. Hill, A. V. S.
Proc Natl Acad Sci U S A, (2018). 115:E3601-E3603

Risk of nontyphoidal Salmonella bacteraemia in African children is modified by STAT4.Gilchrist, J. J. Rautanen, A. Fairfax, B. P. Mills, T. C. Naranbhai, V. Trochet, H. Pirinen, M. Muthumbi, E. Mwarumba, S. Njuguna, P. Mturi, N. Msefula, C. L. Gondwe, E. N. MacLennan, J. M. Chapman, S. J. Molyneux, M. E. Knight, J. C. Spencer, C. C. A. Williams, T. N. MacLennan, C. A. Scott, J. A. G. Hill, A. V. S.
Nat Commun, (2018). 9:1014

Lactate clearance as a prognostic marker of mortality in severely ill febrile children in East Africa.Aramburo, A. Todd, J. George, E. C. Kiguli, S. Olupot-Olupot, P. Opoka, R. O. Engoru, C. Akech, S. O. Nyeko, R. Mtove, G. Gibb, D. M. Babiker, A. G. Maitland, K.
BMC Med, (2018). 16:37

Approaching quality improvement at scale: a learning health system approach in Kenya.Irimu, G. Ogero, M. Mbevi, G. Agweyu, A. Akech, S. Julius, T. Nyamai, R. Githang'a, D. Ayieko, P. English, M. Clinical Information Network Authors, Group
Arch Dis Child, (2018). 103:1013-1019

Prospective Observational Study of Incidence and Preventable Burden of Childhood Tuberculosis, Kenya.Brent, A. J. Nyundo, C. Langat, J. Mulunda, C. Wambua, J. Bauni, E. Sande, J. Park, K. Williams, T. N. Newton, C. R. J. Levin, M. Scott, J. A. G. Kids Tb Study Group
Emerg Infect Dis, (2018). 24:514-523

Single low-dose primaquine for blocking transmission of Plasmodium falciparum malaria - a proposed model-derived age-based regimen for sub-Saharan Africa.Taylor, W. R. Naw, H. K. Maitland, K. Williams, T. N. Kapulu, M. D'Alessandro, U. Berkley, J. A. Bejon, P. Okebe, J. Achan, J. Amambua, A. N. Affara, M. Nwakanma, D. van Geertruyden, J. P. Mavoko, M. Lutumba, P. Matangila, J. Brasseur, P. Piola, P. Randremanana, R. Lasry, E. Fanello, C. Onyamboko, M. Schramm, B. Yah, Z. Jones, J. Fairhurst, R. M. Diakite, M. Malenga, G. Molyneux, M. Rwagacondo, C. Obonyo, C. Gadisa, E. Aseffa, A. Loolpapit, M. Henry, M. C. Dorsey, G. John, C. Sirima, S. B. Barnes, K. I. Kremsner, P. Day, N. P. White, N. J. Mukaka, M.
BMC Med, (2018). 16:11

Realizing effectiveness across continents with hydroxyurea: Enrollment and baseline characteristics of the multicenter REACH study in Sub-Saharan Africa.McGann, P. T. Williams, T. N. Olupot-Olupot, P. Tomlinson, G. A. Lane, A. Luis Reis da Fonseca, J. Kitenge, R. Mochamah, G. Wabwire, H. Stuber, S. Howard, T. A. McElhinney, K. Aygun, B. Latham, T. Santos, B. Tshilolo, L. Ware, R. E. Reach Investigators
Am J Hematol, (2018). 93:537-545

Appropriateness of clinical severity classification of new WHO childhood pneumonia guidance: a multi-hospital, retrospective, cohort study.Agweyu, A. Lilford, R. J. English, M. Clinical Information Network Author, Group
Lancet Glob Health, (2018). 6:e74-e83

Assessment of Myocardial Function and Injury by Echocardiography and Cardiac Biomarkers in African Children With Severe Plasmodium falciparum Malaria.Kotlyar, S. Olupot-Olupot, P. Nteziyaremye, J. Akech, S. O. Uyoga, S. Muhindo, R. Moore, C. L. Maitland, K.
Pediatr Crit Care Med, (2018). 19:179-185

The clinical epidemiology of sickle cell anemia In Africa.Macharia, A. W. Mochamah, G. Uyoga, S. Ndila, C. M. Nyutu, G. Makale, J. Tendwa, M. Nyatichi, E. Ojal, J. Shebe, M. Awuondo, K. O. Mturi, N. Peshu, N. Tsofa, B. Scott, J. A. G. Maitland, K. Williams, T. N.
Am J Hematol, (2018). 93:363-370

Comparable outcomes among trial and nontrial participants in a clinical trial of antibiotics for childhood pneumonia: a retrospective cohort study.Agweyu, A. Oliwa, J. Gathara, D. Muinga, N. Allen, E. Lilford, R. J. English, M.
J Clin Epidemiol, (2018). 94:1-7

Blood Pressure and Arterial Stiffness in Kenyan Adolescents With the Sickle Cell Trait.Etyang, A. O. Wandabwa, C. K. Kapesa, S. Muthumbi, E. Odipo, E. Wamukoya, M. Ngomi, N. Haregu, T. Kyobutungi, C. Williams, T. N. Makale, J. Macharia, A. Cruickshank, J. K. Smeeth, L. Scott, J. A. G.
Am J Epidemiol, (2018). 187:199-205

Community Protection.Fine, P. E. M. Mulholland, K. Scott, J. A. Edmunds, W. J.
Plotkin's Vaccines, (2018). :1512-1531.e5

Children's Oxygen Administration Strategies Trial (COAST): A randomised controlled trial of high flow versus oxygen versus control in African children with severe pneumonia.Maitland, K. Kiguli, S. Opoka, R. O. Olupot-Olupot, P. Engoru, C. Njuguna, P. Bandika, V. Mpoya, A. Bush, A. Williams, T. N. Grieve, R. Sadique, Z. Fraser, J. Harrison, D. Rowan, K.
Wellcome Open Res, (2017). 2:100

No Evidence that Knops Blood Group Polymorphisms Affect Complement Receptor 1 Clustering on Erythrocytes.Swann, O. V. Harrison, E. M. Opi, D. H. Nyatichi, E. Macharia, A. Uyoga, S. Williams, T. N. Rowe, J. A.
Sci Rep, (2017). 7:17825

Correction to: An exploration of mortality risk factors in non-severe pneumonia in children using clinical data from Kenya.Tuti, T. Agweyu, A. Mwaniki, P. Peek, N. English, M. Clinical Information Network Author, Group
BMC Med, (2017). 15:212

Subphenotypes of sickle cell disease in Africa.Piel, F. B. Williams, T. N.
Blood, (2017). 130:2157-2158

An exploration of mortality risk factors in non-severe pneumonia in children using clinical data from Kenya.Tuti, T. Agweyu, A. Mwaniki, P. Peek, N. English, M. Clinical Information Network Author, Group
BMC Med, (2017). 15:201