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Epidemiology & Demography
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Dr. Katherine Gallagher 9
Post - Doc
Biography
Kate completed an MRC(UK)-funded PhD at the London School of Hygiene & Tropical Medicine in 2016 that included studies to assess whether human papillomavirus (HPV) infection increased HIV acquisition in East African women, to evaluate HPV vaccine introduction in Tanzania and to collate 'lessons learnt' during HPV vaccine introduction in 46 low and middle-income countries. Whilst based at the Mwanza Intervention Trials Unit in Tanzania for 2014 and 2015, she also aided the initial set-up of the EBOVAC1 Ebola vaccine Phase 1 trial. As a post-doc, she worked as the London-based academic coordinator of the EBOVAC1 projects including two large phase 2b vaccine trials in Sierra Leone and 2 nested observational studies. Since July 2018 Kate has been based at the KEMRI-Wellcome Trust Research Programme in Kilifi, Kenya, leading an individually randomised trial to assess whether lower/ fractional doses of the two currently available pneumococcal conjugate vaccines (PCV) protect Kenyan infants as well as the full dose schedules. We are also collaborating with Epicentre to complete a cluster randomised controlled trial of fractional dose PCV in Niger. The results could be used to enable countries unable to afford the full cost of the vaccine, to continue delivering it in the childhood immunisation programme in the absence of Gavi support and/or to perform fractional dose mass campaigns in settings with low routine coverage.
Biography
Kate completed an MRC(UK)-funded PhD at the London School of Hygiene & Tropical Medicine in 2016 that included studies to assess whether human papillomavirus (HPV) infection increased HIV acquisition in East African women, to evaluate HPV vaccine introduction in Tanzania and to collate 'lessons learnt' during HPV vaccine introduction in 46 low and middle-income countries. Whilst based at the Mwanza Intervention Trials Unit in Tanzania for 2014 and 2015, she also aided the initial set-up of the EBOVAC1 Ebola vaccine Phase 1 trial. As a post-doc, she worked as the London-based academic coordinator of the EBOVAC1 projects including two large phase 2b vaccine trials in Sierra Leone and 2 nested observational studies. Since July 2018 Kate has been based at the KEMRI-Wellcome Trust Research Programme in Kilifi, Kenya, leading an individually randomised trial to assess whether lower/ fractional doses of the two currently available pneumococcal conjugate vaccines (PCV) protect Kenyan infants as well as the full dose schedules. We are also collaborating with Epicentre to complete a cluster randomised controlled trial of fractional dose PCV in Niger. The results could be used to enable countries unable to afford the full cost of the vaccine, to continue delivering it in the childhood immunisation programme in the absence of Gavi support and/or to perform fractional dose mass campaigns in settings with low routine coverage.
Current Work
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Videos
Publications
Factors predicting mortality in hospitalised HIV-negative children with lower-chest-wall indrawing pneumonia and implications for management.
Gallagher, K. E., Awori, J. O., Knoll, M. D., Rhodes, J., Higdon, M. M., Hammitt, L. L., Prosperi, C., Baggett, H. C., Brooks, W. A., Fancourt, N., Feikin, D. R., Howie, S. R. C., Kotloff, K. L., Tapia, M. D., Levine, O. S., Madhi, S. A., Murdoch, D. R., O'Brien, K. L., Thea, D. M., Baillie, V. L., Ebruke, B. E., Kamau, A., Moore, D. P., Mwananyanda, L., Olutunde, E. O., Seidenberg, P., Sow, S. O., Thamthitiwat, S., Scott, J. A. G.
PLoS One, (2024). 19:e0297159
SARS-CoV-2 seroprevalence and implications for population immunity: Evidence from two Health and Demographic Surveillance System sites in Kenya, February-December 2022.
Kagucia, E. W., Ziraba, A. K., Nyagwange, J., Kutima, B., Kimani, M., Akech, D., Ng'oda, M., Sigilai, A., Mugo, D., Karanja, H., Gitonga, J., Karani, A., Toroitich, M., Karia, B., Otiende, M., Njeri, A., Aman, R., Amoth, P., Mwangangi, M., Kasera, K., Ng'ang'a, W., Voller, S., Ochola-Oyier, L. I., Bottomley, C., Nyaguara, A., Munywoki, P. K., Bigogo, G., Maitha, E., Uyoga, S., Gallagher, K. E., Etyang, A. O., Barasa, E., Mwangangi, J., Bejon, P., Adetifa, I. M. O., Warimwe, G. M., Scott, J. A. G., Agweyu, A.
Influenza Other Respir Viruses, (2023). 17:e13173
Symptom prevalence and secondary attack rate of SARS-CoV-2 in rural Kenyan households: A prospective cohort study.
Gallagher, K. E., Nyiro, J., Agoti, C. N., Maitha, E., Nyagwange, J., Karani, A., Bottomley, C., Murunga, N., Githinji, G., Mutunga, M., Ochola-Oyier, L. I., Kombe, I., Nyaguara, A., Kagucia, E. W., Warimwe, G., Agweyu, A., Tsofa, B., Bejon, P., Scott, J. A. G., Nokes, D. J.
Influenza Other Respir Viruses, (2023). 17:e13185
Population immunity to pneumococcal serotypes in Kilifi, Kenya, before and 6 years after the introduction of PCV10 with a catch-up campaign: an observational study of cross-sectional serosurveys.
Gallagher, K. E., Adetifa, I. M. O., Mburu, C., Bottomley, C., Akech, D., Karani, A., Pearce, E., Wang, Y., Kagucia, E. W., Goldblatt, D., Hammitt, L. L., Scott, J. A. G.
Lancet Infect Dis, (2023). S1473-3099:00206-2
The impact of the COVID-19 pandemic on the provision & utilisation of primary health care services in Goma, Democratic Republic of the Congo, Kambia district, Sierra Leone & Masaka district, Uganda.
Kasonia, K., Tindanbil, D., Kitonsa, J., Baisley, K., Zalwango, F., Enria, L., Mansaray, A., James, M., Nije, Y., Tata, D. T., Lawal, B. J., Drammeh, A., Lowe, B., Mukadi-Bamuleka, D., Mounier-Jack, S., Nakiyimba, F., Obady, P., Muhavi, J., Bangura, J. S., Greenwood, B., Samai, M., Leigh, B., Watson-Jones, D., Kavunga-Membo, H., Ruzagira, E., Gallagher, K. E.
PLoS One, (2023). 18:e0286295