Epidemiology & Demography

Bio

I am a clinical epidemiologist with a specific focus on infectious diseases and vaccines. I trained in clinical medicine at Oxford University, in infectious diseases in London and Newcastle and in epidemiology at the London School of Hygiene & Tropical Medicine (LSHTM). I joined the Programme in 1993 and I was based at the University of Oxford for 15 years before taking up my current position at LSHTM as Professor of Vaccine Epidemiology.

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Current Work

My work has explored the aetiology of pneumonia in children and adults, the incidence of bacterial invasive diseases in children and the impact of conjugate vaccines against H. influenzae type b and pneumococcus. I have run trials of different types of vaccines against pneumococcus, in different schedules (e.g. for neonates) and different doses and I have established various systems of public health surveillance against invasive bacterial disease and SARS-CoV-2. With Tom Williams I set up the Kilifi Health and Demographic Surveillance System (KHDSS) in 2000 and I have worked with many internal and external collaborators to estimate cause specific morbidity and mortality in the KDHSS. Research Group - Katherine Gallagher - Wangeci Kagucia - Esther Muthumbi - John Ojal Other Roles; Director of the Health Protection Research Unit in Immunisation, London School of Hygiene & Tropical Medicine Policy roles: Member – Joint Committee on Vaccination and Immunisation (JCVI) UK Member – World Health Organization Strategic Advisory Group of Experts on Immunisation (WHO SAGE)

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Recent publications

Re-evaluating the impact and cost-effectiveness of pneumococcal conjugate vaccine introduction in 112 low-income and middle-income countries in children younger than 5 years: a modelling study.
Chen, C., Ang, G., Akksilp, K., Koh, J., Scott, J. A. G., Clark, A., Jit, M.
Lancet Glob Health, (2024). 12:e1485-e1497

Identifying delays in healthcare seeking and provision: The Three Delays-in-Healthcare and mortality among infants and children aged 1-59 months.
Garcia Gomez, E., Igunza, K. A., Madewell, Z. J., Akelo, V., Onyango, D., El Arifeen, S., Gurley, E. S., Hossain, M. Z., Chowdhury, M. A. I., Islam, K. M., Assefa, N., Scott, J. A. G., Madrid, L., Tilahun, Y., Orlien, S., Kotloff, K. L., Tapia, M. D., Keita, A. M., Mehta, A., Magaço, A., Torres-Fernandez, D., Nhacolo, A., Bassat, Q., Mandomando, I., Ogbuanu, I., Cain, C. J., Luke, R., Kamara, S. I. B., Legesse, H., Madhi, S., Dangor, Z., Mahtab, S., Wise, A., Adam, Y., Whitney, C. G., Mutevedzi, P. C., Blau, D. M., Breiman, R. F., Tippett Barr, B. A., Rees, C. A.
PLOS Glob Public Health, (2024). 4:e0002494

Age-dependent acquisition of IgG antibodies to Shigella serotypes-a retrospective analysis of seroprevalence in Kenyan children with implications for infant vaccination.
Kapulu, M. C., Muthumbi, E., Otieno, E., Rossi, O., Ferruzzi, P., Necchi, F., Acquaviva, A., Martin, L. B., Orindi, B., Mwai, K., Kibet, H., Mwanzu, A., Bigogo, G. M., Verani, J. R., Mbae, C., Nyundo, C., Agoti, C. N., Nakakana, U. N., Conti, V., Bejon, P., Kariuki, S., Scott, J. A. G., Micoli, F., Podda, A.
Front Immunol, (2024). 15:1340425

Identifying delays in healthcare seeking and provision: The Three Delays-in-Healthcare and mortality among infants and children aged 1-59 months.
Garcia Gomez, E., Igunza, K. A., Madewell, Z. J., Akelo, V., Onyango, D., El Arifeen, S., Gurley, E. S., Hossain, M. Z., Chowdhury, M. A. I., Islam, K. M., Assefa, N., Scott, J. A. G., Madrid, L., Tilahun, Y., Orlien, S., Kotloff, K. L., Tapia, M. D., Keita, A. M., Mehta, A., Magaço, A., Torres-Fernandez, D., Nhacolo, A., Bassat, Q., Mandomando, I., Ogbuanu, I., Cain, C. J., Luke, R., Kamara, S. I. B., Legesse, H., Madhi, S., Dangor, Z., Mahtab, S., Wise, A., Adam, Y., Whitney, C. G., Mutevedzi, P. C., Blau, D. M., Breiman, R. F., Tippett Barr, B. A., Rees, C. A.
PLOS Glob Public Health, (2024). 4:e0002494

Factors predicting mortality in hospitalised HIV-negative children with lower-chest-wall indrawing pneumonia and implications for management.
Gallagher, K. E., Awori, J. O., Knoll, M. D., Rhodes, J., Higdon, M. M., Hammitt, L. L., Prosperi, C., Baggett, H. C., Brooks, W. A., Fancourt, N., Feikin, D. R., Howie, S. R. C., Kotloff, K. L., Tapia, M. D., Levine, O. S., Madhi, S. A., Murdoch, D. R., O'Brien, K. L., Thea, D. M., Baillie, V. L., Ebruke, B. E., Kamau, A., Moore, D. P., Mwananyanda, L., Olutunde, E. O., Seidenberg, P., Sow, S. O., Thamthitiwat, S., Scott, J. A. G.
PLoS One, (2024). 19:e0297159