0709 203000 - Nairobi 0709 983000 - Kilifi
0709 203000 - NRB 0709 983000 - Kilifi
0709 203000 - NRB | 0709 983000 - Kilifi

Epidemiology & Demography

Bio


I am a clinical epidemiologist with a specific focus on infectious diseases and vaccines. I trained in clinical medicine at Oxford University, in infectious diseases in London and Newcastle and in epidemiology at the London School of Hygiene & Tropical Medicine (LSHTM). I joined the Programme in 1993 and I was based at the University of Oxford for 15 years before taking up my current position at LSHTM as Professor of Vaccine Epidemiology.

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Current Work


My work has explored the aetiology of pneumonia in children and adults, the incidence of bacterial invasive diseases in children and the impact of conjugate vaccines against H. influenzae type b and pneumococcus. I have run trials of different types of vaccines against pneumococcus, in different schedules (e.g. for neonates) and different doses and I have established various systems of public health surveillance against invasive bacterial disease and SARS-CoV-2. With Tom Williams I set up the Kilifi Health and Demographic Surveillance System (KHDSS) in 2000 and I have worked with many internal and external collaborators to estimate cause specific morbidity and mortality in the KDHSS. Research Group - Katherine Gallagher - Wangeci Kagucia - Esther Muthumbi - John Ojal Other Roles; Director of the Health Protection Research Unit in Immunisation, London School of Hygiene & Tropical Medicine Policy roles: Member – Joint Committee on Vaccination and Immunisation (JCVI) UK Member – World Health Organization Strategic Advisory Group of Experts on Immunisation (WHO SAGE)

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Recent publications


Assessing the Impact of SARS-CoV-2 Spike Mutations on Antibody Binding: A Comparative Assessment of the Wuhan and JN.1 Variants' Full-Length Spikes in a Multiplex Luminex Assay.
Waweru, G., Nyakundi, R., Kutima, B., Owuor, S., Konyino, G., Gitonga, J., Lugano, D., Maina, A., Musyoki, J., Ochola, L., Omondi, M., Kariuki, C. K., Ogongo, P., Mwachari, C., Shee, F., Agoti, C., Sande, C., Uyoga, S., Kagucia, E., Agweyu, A., Bejon, P., Scott, J. A. G., Warimwe, G. M., Ochola-Oyier, L. I., Nyagwange, J.
Viruses, (2025). 17:

Modelling the relative contribution of infection, routine vaccination and supplementary immunisation activities to measles seroconversion in Kenyan Children.
Mburu, C., Ojal, J., Selim, R., Ombati, R., Akech, D., Karia, B., Tuju, J., Sigilai, A., Smits, G., Gageldonk, P. V., Klis, F. V., Kagucia, E., Scott, A., Adetifa, I., Flasche, S.
PLoS Comput Biol, (2025). 21:e1013531

Major Causes of Perinatal and Paediatric Mortality in Sub-Saharan Africa and South Asia: Adjustment for Selection Bias in the CHAMPS Network.
Vyas, K. J., Muir, J. A., Madewell, Z. J., Gupta, P. M., Blau, D. M., Arifeen, S. E., Gurley, E. S., Chowdhury, A. I., Islam, K. M., Rahman, A., Scott, J. A. G., Assefa, N., Madrid, L., Asefa, Y. A., Abdullahi, Y. Y., Onyango, D., Akelo, V., Tippett-Barr, B. A., Aol, G., Sow, S. O., Kotloff, K. L., Tapia, M. D., Keita, A. M., Chawla, K., Bassat, Q., Mandomando, I., Nhacolo, A., Sacoor, C., Ogbuanu, I., Kowuor, D., Duduyemi, B., Moseray, A., Squire, J. S., Madhi, S., Mahtab, S., Adam, Y., Wise, A., Machemedza, T., Whitney, C. G.
Paediatr Perinat Epidemiol, (2025). :

Modelling the relative contribution of infection, routine vaccination and supplementary immunisation activities to measles seroconversion in Kenyan Children.
Mburu, C., Ojal, J., Selim, R., Ombati, R., Akech, D., Karia, B., Tuju, J., Sigilai, A., Smits, G., van Gageldonk, P., van der Klis, F., Kagucia, E., Scott, A., Adetifa, I., Flasche, S.
PLoS Comput Biol, (2025). 21:e1013531

Pneumococcal carriage prevalence, serotype distribution, and vaccine coverage in Ethiopia 12 years after pneumococcal vaccine introduction.
Bizuayehu, H. Y., Kebede, Y., Deressa, M., Solomon, E., Marami, D., Karani, A., Gardiner, E., Dessie, Y., Scott, J. A. G., Gallagher, K. E.
Vaccine, (2025). 64:127762