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Bio


Charles was born in Kenya, qualified in Cape Town, South Africa, with postgraduate training in Paediatrics in Manchester and London, United Kingdom. As a lecturer at University of Oxford, he returned to Kilifi Kenya in 1989, to help set up an unit to study severe malaria in African children. Thereafter he spent 2 years as a Post-doctoral fellow at Johns Hopkins, USA; studying mechanisms of brain damage in central nervous system infections. He completed his training in Paediatric Neurology at Great Ormond Street Hospital, UK. In 1998 he was awarded a Wellcome Trust Senior Clinical Fellowship at University College London, to return to Kilifi, to study CNS infections in children. He has published on a wide variety of subjects concerning sick children in tropical countries. In 2011 he took up a professorship in Psychiatry at the University of Oxford to concentrate of neurological and mental illness disorders in children living in Africa.

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Current Work


He conducts research on CNS infections in children; epidemiological studies of epilepsy and neurological impairment; tetanus, jaundice and sepsis in neonates. At present he is conducting studies of Autism and Epilepsy in Africa and working on sickle cell disease in Tanzania.

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Recent publications


Severe anaemia and invasive bacterial infections in Kenyan children: a 26-year hospital surveillance observational study.
Abuga, K. M. Muriuki, J. M. Mutua, A. M. Wambui, K. M. Mturi, N. Mohammed, S. Fondo, J. K. Mwarumba, S. Ngetsa, C. J. Newton, C. R. Maitland, K. Bejon, P. MacLennan, C. A. Nairz, M. Scott, J. A. G. Williams, T. N. Atkinson, S. H.
Lancet Glob Health, (2026). 14:103976

Severe anaemia and invasive bacterial infections in Kenyan children: a 26-year hospital surveillance observational study.
Abuga, K. M. Muriuki, J. M. Mutua, A. M. Wambui, K. M. Mturi, N. Mohammed, S. Fondo, J. K. Mwarumba, S. Ngetsa, C. J. Newton, C. R. Maitland, K. Bejon, P. MacLennan, C. A. Nairz, M. Scott, J. A. G. Williams, T. N. Atkinson, S. H.
Lancet Glob Health, (2026). 14:103976

Carrying the weight in silence: lived realities of epilepsy caregivers in Shai Osudoku and Ningo Prampram.
Asiamah, S. Akpalu, A. Darkwa, E. K. Mahone, S. Newton, C. R. Sen, A. Sander, J. W. Tabong, P. T. Nwameme, A. U. Cross, H. Atuguba, F. Williams, J. E. Sottie, C. Adjei, P. On the behalf of the, EPInA investigatorsElsevier
Epilepsy Behav, (2026). 183:111159

The prevalence and determinants of epilepsy in Ghana: A population-based study in two districts using a three-stage approach.
Darkwa, E. K. Asiamah, S. Awini, E. Sottie, C. Godi, A. Williams, J. E. Atuguba, F. Adjei, A. Akpalu, A. Cross, J. H. Sander, J. W. Sen, A. Newton, C. R. Danso-Appiah, A. Adjei, P. E. PInA Investigators
Epilepsia, (2026). :

Accuracy of epilepsy screening tools in community and primary care settings across countries in Sub-Saharan Africa: systematic review and meta-analysis protocol.
Darkwa, E. K. Cross, J. H. Adjei, P. Newton, C. R. Sen, A. Akpalu, A. Sander, J. W. Danso-Appiah, A.
BMJ Open, (2026). 16:e116684

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