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Researcher
Prof. Kathryn Maitland
Principal Investigator
KEMRI | Wellcome Trust
Publications (215)
A complete list of publications by Prof. Kathryn Maitland. Use the filters to refine by year, journal or keyword.
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2026
Sevuparin in children with severe malaria: a phase I safety and dose-finding trial
Chaponda, M. Gwasupika, J. Connon, R. Tshilab Kabwit, et al.
Nat Commun. 2026; 17
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2026
Severe anaemia and invasive bacterial infections in Kenyan children: a 26-year hospital surveillance observational study
Abuga, K. M. Muriuki, J. M. Mutua, A. M. Wambui, et al.
Lancet Glob Health. 2026; 14:103976
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2026
Severe anaemia and invasive bacterial infections in Kenyan children: a 26-year hospital surveillance observational study
Abuga, K. M. Muriuki, J. M. Mutua, A. M. Wambui, et al.
Lancet Glob Health. 2026; 14:103976
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2026
Intravenous Artesunate in Artemisinin-Resistant Severe Malaria in Uganda
Maitland, K. Okao, M. Conrad, M. D. Etwop, et al.
N Engl J Med. 2026; 394:2380-2382
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2026
Intravenous rehydration in children with severe malnutrition and severe dehydration: a systematic review and meta-analysis
Dewez, J. E. Ouattara, S. M. Sunyoto, T. Mogaka, et al.
Arch Dis Child. 2026
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2026
Synthesis and Standardization of Outcomes in Severe Malaria Treatment Trials: Protocol for the Development of a Core Outcome Set (the COSSMaT Study)
Asamoah, G. D. Love, S. B. Gibb, D. M. Maitland, et al.
JMIR Res Protoc. 2026; 15:e78616
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2026
Nasopharyngeal Microbiome Composition and its Clinical Correlates in Children Hospitalized with Severe Pneumonia in East Africa
Makori, T. O. Gicheru, E. T. Mburu, M. W. Sada, et al.
J Infect Dis. 2026
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2026
Oral rehydration for severe malnutrition in children with moderate and severe dehydration (GASTROSAM): a phase 2, open-label, superiority randomised controlled trial
Maitland, K. Sainna, H. Connon, R. Ouattara, et al.
Lancet Child Adolesc Health. 2026; 10:319-329
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2026
Intravenous Rehydration for Severe Acute Malnutrition with Gastroenteritis. Reply
Maitland, K. Petrucci, R. Thomson, J.
N Engl J Med. 2026; 394:202-203
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2026
A cost-consequence analysis of the children's administration oxygenation strategies trial (COAST) in severe pneumonia
Carroll, O. U. Grieve, R. Kiguli, S. Olupot-Olupot, et al.
PLOS Glob Public Health. 2026; 6:e0005654
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2026
Gut microbial diversity impacts carbohydrate fermentation by children with severe acute malnutrition
Bisht, A. Ahn-Jarvis, J. Corbin, K. Harris, et al.
iScience. 2026; 29:114640
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2025
Single low dose primaquine to block the transmission of Plasmodium falciparum-proposed stand-alone and ACT-adapted regimens
Taylor, W. R. J. Olupot-Olupot, P. Onyamboko, M. A. Chimjinda, et al.
BMC Med. 2025; 23:397
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2025
The aetiologies, mortality, and disability of non-traumatic coma in African children: a systematic review and meta-analysis
Ray, S. T. J. Fuller, C. E. Boubour, A. Tshimangani, et al.
Lancet Glob Health. 2025; 13:e1043-e1056
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2024
Novel gastrointestinal tools (GI Tools) for evaluating gut functional capacity in adults with environmental enteropathy in Zambia and Zimbabwe: A cross-sectional study protocol
Phiri, T. N. Weatherill, J. W. Monford-Sanchez, E. Serrano-Contreras, et al.
F1000Res. 2024; 13:956
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2025
Epidemiological dynamics of influenza B virus across multiple seasons in Kenya and Uganda inferred from sequence data, 2010-2021
Nyarango, B. K. Owuor, D. C. Isoe, E. Mutunga, et al.
BMC Infect Dis. 2025; 25:1080
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2025
Effect of nutritional supplementation with lipid-based therapeutic food on body composition of non-severely malnourished African children aged 6-59 months hospitalized with severe pneumonia
Nalwanga, D. Musiime, V. Kiguli, S. Olupot-Olupot, et al.
J Trop Pediatr. 2025; 71
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2025
Mortality among children aged 28 days-17 years with pneumonia who are not severely undernourished and the effect of macronutrient supplementation: a systematic review and meta-analysis
Nalwanga, D. Kinengyere, A. A. Kiggwe, A. Negash, et al.
BMJ Open. 2025; 15:e091766
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2025
Supplementation with ready-to-use therapeutic food has no effect on adverse outcomes among undernourished children aged 6-59 months with severe pneumonia
Nalwanga, D. Giallongo, E. Musiime, V. Kiguli, et al.
Front Nutr. 2025; 12:1507360
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2025
Intravenous Rehydration for Severe Acute Malnutrition with Gastroenteritis
Maitland, K. Ouattara, S. M. Sainna, H. Chara, et al.
N Engl J Med. 2025; 393:1257-1268
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2025
Early weaning from oxygen therapy in African children with severe pneumonia
Maitland, K. Giallongo, E. Hamaluba, M. Alaroker, et al.
BMC Med. 2025; 23:366
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2025
Fluid Resuscitation in Pediatric Cerebral Malaria: Insights from the FEAST Trial and Further Evidence from Malawi
George, E. C. Maitland, K.
Am J Trop Med Hyg. 2025; 113:1-2
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2026
Cardiac output measurement in Malawian children ages 2 months-12 years hospitalised with severe anaemia (COM-TRACT)
Chintolo, E. Connon, R. George, E. C. Chagaluka, et al.
Int Health. 2026; 18:600-609
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2025
Comparing HemoCue(R) and Quantitative Buffy Coat(R) and Coulter Counter-measured haemoglobin concentrations in African children with acute uncomplicated malaria: a Bland-Altman analysis
Ayuen, D. S. Olupot-Olupot, P. Muhindo, R. Onyamboko, et al.
Malar J. 2025; 24:77
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2025
Plasma folate dynamics in Plasmodium falciparum-infected African children treated with artemisinin combination therapy and single low-dose primaquine or placebo
Ajayi, S. Onyamboko, M. A. Olupot-Olupot, P. Ayuen, et al.
Malar J. 2025; 24:342
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2024
Legume-supplemented feed for children hospitalised with severe malnutrition: a phase II trial
Walsh, K. Kiosa, A. Olupot-Olupot, P. Alaroker, et al.
Br J Nutr. 2024; 132:372-381
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2021
Gastroenteritis Rehydration Of children with Severe Acute Malnutrition (GASTROSAM): A Phase II Randomised Controlled trial: Trial Protocol
Olupot-Olupot, P. Aloroker, F. Mpoya, A. Mnjalla, et al.
Wellcome Open Res. 2021; 6:160
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2024
Inpatient and postdischarge mortality among children with anaemia and malaria parasitaemia in Kenya: a cohort study
Ngari, M. Mwangome, M. Ouma, N. Nyaguara, et al.
BMJ Glob Health. 2024; 9
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2024
Is fat mass a better predictor of 6-month survival than muscle mass among African children aged 6-59 months with severe pneumonia?
Nalwanga, D. Musiime, V. Kiguli, S. Olupot-Olupot, et al.
BMC Nutr. 2024; 10:130
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2023
Mortality among non-severely under nourished children with pneumonia globally: protocol for a systematic review and meta-analysis
Nalwanga, D. Bakker, C. Kiggwe, A. Negash, et al.
Wellcome Open Res. 2023; 8:551
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2024
A Phase I trial of Non-invasive Ventilation and seizure prophylaxis with levetiracetam In Children with Cerebral Malaria Trial (NOVICE-M Trial)
Maitland, K. Obonyo, N. Hamaluba, M. Ogoda, et al.
Wellcome Open Res. 2024; 9:281
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2023
SEVUparin as a potential Adjunctive Treatment in children with severe malaria: A phase I trial safety and dose finding trial (SEVUSMAART)
Maitland, K. Hamaluba, M. Obonyo, N. Oguda, et al.
Wellcome Open Res. 2023; 8:484
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2024
The double burden of malnutrition in individuals: Identifying key challenges and re-thinking research focus
Kiosia, A. Dagbasi, A. Berkley, J. A. Wilding, et al.
Nutr Bull. 2024; 49:132-145
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2024
Nutritional supplementation in children with severe pneumonia in Uganda and Kenya (COAST-Nutrition): a phase 2 randomised controlled trial
Kiguli, S. Olupot-Olupot, P. Hamaluba, M. Giallongo, et al.
EClinicalMedicine. 2024; 72:102640
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2024
Core sepsis-related competencies for medical students: an international consensus by Delphi technique
Gomersall, E. L. M. Ling, L. Reinhart, K. Bion, et al.
BMC Med Educ. 2024; 24:653
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2024
Azithromycin in severe malaria bacterial co-infection in African children (TABS-PKPD): a phase II randomised controlled trial
Connon, R. Olupot-Olupot, P. Pistorius, A. M. A. Okiror, et al.
BMC Med. 2024; 22:516
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2021
Development of a legume-enriched feed for treatment of severe acute malnutrition
Walsh, K. Delamare de la Villenaise de Chenevarin, G. McGurk, J. Maitland, et al.
Wellcome Open Res. 2021; 6:206
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2023
Blood transfusion for children in sub-Saharan Africa: 200 years on
Uyoga, S. Mbanya, D. George, E. C. Maitland, et al.
Lancet Child Adolesc Health. 2023; 7:525-526
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2023
Safety of age-dosed, single low-dose primaquine in children with glucose-6-phosphate dehydrogenase deficiency who are infected with Plasmodium falciparum in Uganda and the Democratic Republic of the Congo: a randomised, double-blind, placebo-controlled, non-inferiority trial
Taylor, W. R. Olupot-Olupot, P. Onyamboko, M. A. Peerawaranun, et al.
Lancet Infect Dis. 2023; 23:471-483
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2023
Non-O ABO blood group genotypes differ in their associations with Plasmodium falciparum rosetting and severe malaria
Opi, D. H. Ndila, C. M. Uyoga, S. Macharia, et al.
PLoS Genet. 2023; 19:e1010910
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2023
Factors affecting haemoglobin dynamics in African children with acute uncomplicated Plasmodium falciparum malaria treated with single low-dose primaquine or placebo
Onyamboko, M. A. Olupot-Olupot, P. Were, W. Namayanja, et al.
BMC Med. 2023; 21:397
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2021
Pharmacokinetics and pharmacodynamics of azithromycin in severe malaria bacterial co-infection in African children (TABS-PKPD): a protocol for a Phase II randomised controlled trial
Olupot-Olupot, P. Okiror, W. Mnjalla, H. Muhindo, et al.
Wellcome Open Res. 2021; 6:161
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2023
Resuscitation-associated endotheliopathy (RAsE): a conceptual framework based on a systematic review and meta-analysis
Obonyo, N. G. Sela, D. P. Raman, S. Rachakonda, et al.
Syst Rev. 2023; 12:221
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2023
Cardiovascular abnormalities in chest radiographs of children with pneumonia, Uganda
Nabawanuka, E. Ameda, F. Erem, G. Bugeza, et al.
Bull World Health Organ. 2023; 101:202-210
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2023
Pharmacokinetics of single low dose primaquine in Ugandan and Congolese children with falciparum malaria
Mukaka, M. Onyamboko, M. A. Olupot-Olupot, P. Peerawaranun, et al.
EBioMedicine. 2023; 96:104805
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2023
Avoid re-interpreting fluid bolus recommendations for low-income settings
Kiguli, S. Maitland, K. George, E.
Lancet Child Adolesc Health. 2023; 7:e18
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2023
Evaluation of Acceptability, Functionality, and Validity of a Passive Image-Based Dietary Intake Assessment Method in Adults and Children of Ghanaian and Kenyan Origin Living in London, UK
Jobarteh, M. L. McCrory, M. A. Lo, B. Triantafyllidis, et al.
Nutrients. 2023; 15
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2022
Improving the diagnosis of severe malaria in African children using platelet counts and plasma PfHRP2 concentrations
Watson, J. A. Uyoga, S. Wanjiku, P. Makale, et al.
Sci Transl Med. 2022; 14:eabn5040
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2022
The impact of malaria-protective red blood cell polymorphisms on parasite biomass in children with severe Plasmodium falciparum malaria
Uyoga, S. Watson, J. A. Wanjiku, P. Rop, et al.
Nat Commun. 2022; 13:3307
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2022
Sickle cell anaemia and severe Plasmodium falciparum malaria: a secondary analysis of the Transfusion and Treatment of African Children Trial (TRACT)
Uyoga, S. Olupot-Olupot, P. Connon, R. Kiguli, et al.
Lancet Child Adolesc Health. 2022; 6:606-613
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2022
A predictive algorithm for identifying children with sickle cell anemia among children admitted to hospital with severe anemia in Africa
Olupot-Olupot, P. Connon, R. Kiguli, S. Opoka, et al.
Am J Hematol. 2022; 97:527-536
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2022
A Clinical and Physiological Prospective Observational Study on the Management of Pediatric Shock in the Post-Fluid Expansion as Supportive Therapy Trial Era
Obonyo, N. G. Olupot-Olupot, P. Mpoya, A. Nteziyaremye, et al.
Pediatr Crit Care Med. 2022; 23:502-513
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2022
High false discovery rate of the Architect anti-HCV screening test in blood donors in Uganda and evaluation of an algorithm for confirmatory testing
Lucey, O. Acana, S. Olupot-Olupot, P. Muhindo, et al.
Vox Sang. 2022; 117:1360-1367
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2022
BIRC6 modifies risk of invasive bacterial infection in Kenyan children
Gilchrist, J. J. Kariuki, S. N. Watson, J. A. Band, et al.
Elife. 2022; 11
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2022
Whole blood versus red cell concentrates for children with severe anaemia: a secondary analysis of the Transfusion and Treatment of African Children (TRACT) trial
George, E. C. Uyoga, S. M'Baya, B. Kyeyune Byabazair, et al.
Lancet Glob Health. 2022; 10:e360-e368
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2021
Improving statistical power in severe malaria genetic association studies by augmenting phenotypic precision
Watson, J. A. Ndila, C. M. Uyoga, S. Macharia, et al.
Elife. 2021; 10
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2021
Plasma Plasmodium falciparum Histidine-rich Protein 2 Concentrations in Children With Malaria Infections of Differing Severity in Kilifi, Kenya
Uyoga, S. Wanjiku, P. Rop, J. C. Makale, et al.
Clin Infect Dis. 2021; 73:e2415-e2423
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2021
Point-of-care haemoglobin testing in African hospitals: a neglected essential diagnostic test
Uyoga, S. George, E. C. Bates, I. Olupot-Olupot, et al.
Br J Haematol. 2021; 193:894-901
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2021
Transfusion management of severe anaemia in African children: a consensus algorithm
Maitland, K. Kiguli, S. Olupot-Olupot, P. Opoka, et al.
Br J Haematol. 2021; 193:1247-1259
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2021
Randomised controlled trial of oxygen therapy and high-flow nasal therapy in African children with pneumonia
Maitland, K. Kiguli, S. Olupot-Olupot, P. Hamaluba, et al.
Intensive Care Med. 2021; 47:566-576
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2021
Children's Oxygen Administration Strategies And Nutrition Trial (COAST-Nutrition): a protocol for a phase II randomised controlled trial
Kiguli, S. Olopot-Olupot, P. Alaroker, F. Engoru, et al.
Wellcome Open Res. 2021; 6:221
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2021
Incidence and predictors of hospital readmission in children presenting with severe anaemia in Uganda and Malawi: a secondary analysis of TRACT trial data
Connon, R. George, E. C. Olupot-Olupot, P. Kiguli, et al.
BMC Public Health. 2021; 21:1480
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2021
Modifying gut integrity and microbiome in children with severe acute malnutrition using legume-based feeds (MIMBLE): A pilot trial
Calder, N. Walsh, K. Olupot-Olupot, P. Ssenyondo, et al.
Cell Rep Med. 2021; 2:100280
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2020
The cost-effectiveness of prophylaxis strategies for individuals with advanced HIV starting treatment in Africa
Walker, S. M. Cox, E. Revill, P. Musiime, et al.
J Int AIDS Soc. 2020; 23:e25469
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2020
Glucose-6-phosphate dehydrogenase deficiency and susceptibility to childhood diseases in Kilifi, Kenya
Uyoga, S. Macharia, A. W. Ndila, C. M. Nyutu, et al.
Blood Adv. 2020; 4:5942-5950
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2020
Sepsis hysteria? Not for children - Authors' reply
Singer, M. Inada-Kim, M. Peters, M. Maitland, et al.
Lancet. 2020; 396:1333-1334
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2020
Characterising demographics, knowledge, practices and clinical care among patients attending sickle cell disease clinics in Eastern Uganda
Olupot-Olupot, P. Wabwire, H. Ndila, C. Adong, et al.
Wellcome Open Res. 2020; 5:87
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2020
The clinical spectrum of severe childhood malaria in Eastern Uganda
Olupot-Olupot, P. Engoru, C. Nteziyaremye, J. Chebet, et al.
Malar J. 2020; 19:322
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2020
Development and Validation of an Objective, Passive Dietary Assessment Method for Estimating Food and Nutrient Intake in Households in Low- and Middle-Income Countries: A Study Protocol
Jobarteh, M. L. McCrory, M. A. Lo, B. Sun, et al.
Curr Dev Nutr. 2020; 4:nzaa020
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2019
Haematological quality and age of donor blood issued for paediatric transfusion to four hospitals in sub-Saharan Africa
Uyoga, S. Mpoya, A. Olupot-Olupot, P. Kiguli, et al.
Vox Sang. 2019; 114:340-348
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2019
The indirect health effects of malaria estimated from health advantages of the sickle cell trait
Uyoga, S. Macharia, A. W. Ndila, C. M. Nyutu, et al.
Nat Commun. 2019; 10:856
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2019
The epidemiology of sickle cell disease in children recruited in infancy in Kilifi, Kenya: a prospective cohort study
Uyoga, S. Macharia, A. W. Mochamah, G. Ndila, et al.
Lancet Glob Health. 2019; 7:e1458-e1466
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2019
Mortality after inpatient treatment for diarrhea in children: a cohort study
Talbert, A. Ngari, M. Bauni, E. Mwangome, et al.
BMC Med. 2019; 17:20
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2019
Effect of 10-valent pneumococcal conjugate vaccine on the incidence of radiologically-confirmed pneumonia and clinically-defined pneumonia in Kenyan children: an interrupted time-series analysis
Silaba, M. Ooko, M. Bottomley, C. Sande, et al.
Lancet Glob Health. 2019; 7:e337-e346
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2019
Fluid resuscitation with 0.9% saline alters haemostasis in an ovine model of endotoxemic shock
Passmore, M. R. Obonyo, N. G. Byrne, L. Boon, et al.
Thromb Res. 2019; 176:39-45
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2019
Pre-clinical study protocol: Blood transfusion in endotoxaemic shock
Obonyo, N. G. Byrne, L. Tung, J. P. Simonova, et al.
MethodsX. 2019; 6:1124-1132
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2019
Observational study: 27 years of severe malaria surveillance in Kilifi, Kenya
Njuguna, P. Maitland, K. Nyaguara, A. Mwanga, et al.
BMC Med. 2019; 17:124
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2019
Transfusion Timing and Volume in African Children with Severe Anemia. Reply
Maitland, K. Olupot-Olupot, P. Walker, A. S.
N Engl J Med. 2019; 381:1687-1688
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2019
Co-trimoxazole or multivitamin multimineral supplement for post-discharge outcomes after severe anaemia in African children: a randomised controlled trial
Maitland, K. Olupot-Olupot, P. Kiguli, S. Chagaluka, et al.
Lancet Glob Health. 2019; 7:e1435-e1447
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2019
Transfusion Volume for Children with Severe Anemia in Africa
Maitland, K. Olupot-Olupot, P. Kiguli, S. Chagaluka, et al.
N Engl J Med. 2019; 381:420-431
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2019
Informing thresholds for paediatric transfusion in Africa: the need for a trial
Maitland, K. Ohuma, E. O. Mpoya, A. Uyoga, et al.
Wellcome Open Res. 2019; 4:27
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2019
Immediate Transfusion in African Children with Uncomplicated Severe Anemia
Maitland, K. Kiguli, S. Olupot-Olupot, P. Engoru, et al.
N Engl J Med. 2019; 381:407-419
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2019
Emergency fluid bolus therapy studies: first do no harm
Maitland, K.
Arch Dis Child. 2019; 104:409-410
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2019
Gastroenteritis aggressive versus slow treatment for rehydration (GASTRO): a phase II rehydration trial for severe dehydration: WHO plan C versus slow rehydration
Houston, K. A. Gibb, J. Olupot-Olupot, P. Obonyo, et al.
BMC Med. 2019; 17:122
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2019
Mortality risk over time after early fluid resuscitation in African children
George, E. C. Kiguli, S. Olupot, P. O. Opoka, et al.
Crit Care. 2019; 23:377
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2019
Healthcare-provider perceptions of barriers to oxygen therapy for paediatric patients in three government-funded eastern Ugandan hospitals; a qualitative study
Dauncey, J. W. Olupot-Olupot, P. Maitland, K.
BMC Health Serv Res. 2019; 19:335
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2019
Assessment of Myocardial Function in Kenyan Children With Severe, Acute Malnutrition: The Cardiac Physiology in Malnutrition (CAPMAL) Study
Brent, B. Obonyo, N. Akech, S. Shebbe, et al.
JAMA Netw Open. 2019; 2:e191054
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2018
Modifying Intestinal Integrity and Micro Biome in Severe Malnutrition with Legume-Based Feeds (MIMBLE 2.0): protocol for a phase II refined feed and intervention trial
Walsh, K. Calder, N. Olupot-Olupot, P. Ssenyondo, et al.
Wellcome Open Res. 2018; 3:95
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2018
Single low-dose primaquine for blocking transmission of Plasmodium falciparum malaria - a proposed model-derived age-based regimen for sub-Saharan Africa
Taylor, W. R. Naw, H. K. Maitland, K. Williams, et al.
BMC Med. 2018; 16:11
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2018
Late Presentation With HIV in Africa: Phenotypes, Risk, and Risk Stratification in the REALITY Trial
Siika, A. McCabe, L. Bwakura-Dangarembizi, M. Kityo, et al.
Clin Infect Dis. 2018; 66:S140-S146
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2018
Inflammation and lung injury in an ovine model of fluid resuscitated endotoxemic shock
Passmore, M. R. Byrne, L. Obonyo, N. G. See Hoe, et al.
Respir Res. 2018; 19:231
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2018
Two complement receptor one alleles have opposing associations with cerebral malaria and interact with alpha(+)thalassaemia
Opi, D. H. Swann, O. Macharia, A. Uyoga, et al.
Elife. 2018; 7
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2018
Reliability and validity of the World Health Organization reading standards for paediatric chest radiographs used in the field in an impact study of Pneumococcal Conjugate Vaccine in Kilifi, Kenya
Ominde, M. Sande, J. Ooko, M. Bottomley, et al.
PLoS One. 2018; 13:e0200715
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2018
Evaluation of the diagnostic accuracy and cost of different methods for the assessment of severe anaemia in hospitalised children in Eastern Uganda
Olupot-Olupot, P. Prevatt, N. Engoru, C. Nteziyaremye, et al.
Wellcome Open Res. 2018; 3:130
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2018
Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study
Ndila, C. M. Uyoga, S. Macharia, A. W. Nyutu, et al.
Lancet Haematol. 2018; 5:e333-e345
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2018
The clinical epidemiology of sickle cell anemia In Africa
Macharia, A. W. Mochamah, G. Uyoga, S. Ndila, et al.
Am J Hematol. 2018; 93:363-370
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2018
Assessment of Myocardial Function and Injury by Echocardiography and Cardiac Biomarkers in African Children With Severe Plasmodium falciparum Malaria
Kotlyar, S. Olupot-Olupot, P. Nteziyaremye, J. Akech, et al.
Pediatr Crit Care Med. 2018; 19:179-185
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2018
Rapid intravenous rehydration of children with acute gastroenteritis and dehydration: a systematic review and meta-analysis
Iro, M. A. Sell, T. Brown, N. Maitland, et al.
BMC Pediatr. 2018; 18:44
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2018
Implications for paediatric shock management in resource-limited settings: a perspective from the FEAST trial
Houston, K. A. George, E. C. Maitland, K.
Crit Care. 2018; 22:119
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2018
Unintended Consequences: Fluid Resuscitation Worsens Shock in an Ovine Model of Endotoxemia
Byrne, L. Obonyo, N. G. Diab, S. D. Dunster, et al.
Am J Respir Crit Care Med. 2018; 198:1043-1054
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2018
An Ovine Model of Hyperdynamic Endotoxemia and Vital Organ Metabolism
Byrne, L. Obonyo, N. G. Diab, S. Dunster, et al.
Shock. 2018; 49:99-107
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2018
Lactate clearance as a prognostic marker of mortality in severely ill febrile children in East Africa
Aramburo, A. Todd, J. George, E. C. Kiguli, et al.
BMC Med. 2018; 16:37
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2017
High Frequency of Blackwater Fever Among Children Presenting to Hospital With Severe Febrile Illnesses in Eastern Uganda
Olupot-Olupot, P. Engoru, C. Uyoga, S. Muhindo, et al.
Clin Infect Dis. 2017; 64:939-946
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2017
Myocardial and haemodynamic responses to two fluid regimens in African children with severe malnutrition and hypovolaemic shock (AFRIM study)
Obonyo, N. Brent, B. Olupot-Olupot, P. Boele van Hensbroek, et al.
Crit Care. 2017; 21:103
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2017
Gender Parity in Critical Care Medicine
Mehta, S. Burns, K. E. A. Machado, F. R. Fox-Robichaud, et al.
Am J Respir Crit Care Med. 2017; 196:425-429
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2017
Children's Oxygen Administration Strategies Trial (COAST): A randomised controlled trial of high flow versus oxygen versus control in African children with severe pneumonia
Maitland, K. Kiguli, S. Opoka, R. O. Olupot-Olupot, et al.
Wellcome Open Res. 2017; 2:100
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2017
Gastroenteritis Aggressive Versus Slow Treatment For Rehydration (GASTRO). A pilot rehydration study for severe dehydration: WHO plan C versus slower rehydration
Houston, K. A. Gibb, J. G. Mpoya, A. Obonyo, et al.
Wellcome Open Res. 2017; 2:62
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2017
Oral rehydration of malnourished children with diarrhoea and dehydration: A systematic review
Houston, K. A. Gibb, J. G. Maitland, K.
Wellcome Open Res. 2017; 2:66
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2017
Intravenous rehydration of malnourished children with acute gastroenteritis and severe dehydration: A systematic review
Houston, K. A. Gibb, J. G. Maitland, K.
Wellcome Open Res. 2017; 2:65
-
2017
Enhanced Prophylaxis plus Antiretroviral Therapy for Advanced HIV Infection in Africa
Hakim, J. Musiime, V. Szubert, A. J. Mallewa, et al.
N Engl J Med. 2017; 377:233-245
-
2016
Effects of volume resuscitation on the microcirculation in animal models of lipopolysaccharide sepsis: a systematic review
Obonyo, N. G. Fanning, J. P. Ng, A. S. Pimenta, et al.
Intensive Care Med Exp. 2016; 4:38
-
2016
Validation of triple pass 24-hour dietary recall in Ugandan children by simultaneous weighed food assessment
Nightingale, H. Walsh, K. J. Olupot-Olupot, P. Engoru, et al.
BMC Nutr. 2016; 2
-
2016
Pediatric blood transfusion practices at a regional referral hospital in Kenya
Nabwera, H. M. Fegan, G. Shavadia, J. Denje, et al.
Transfusion. 2016; 56:2732-2738
-
2016
Severe Malaria in African Children - The Need for Continuing Investment
Maitland, K.
N Engl J Med. 2016; 375:2416-2417
-
2016
Increased adhesion of Plasmodium falciparum infected erythrocytes to ICAM-1 in children with acute intestinal injury
Church, J. A. Nyamako, L. Olupot-Olupot, P. Maitland, et al.
Malar J. 2016; 15:54
-
2015
Transfusion and Treatment of severe anaemia in African children (TRACT): a study protocol for a randomised controlled trial
Mpoya, A. Kiguli, S. Olupot-Olupot, P. Opoka, et al.
Trials. 2015; 16:593
-
2015
Management of severe paediatric malaria in resource-limited settings
Maitland, K.
BMC Med. 2015; 13:42
-
2015
Anaemia and blood transfusion in African children presenting to hospital with severe febrile illness
Kiguli, S. Maitland, K. George, E. C. Olupot-Olupot, et al.
BMC Med. 2015; 13:21
-
2015
Safety and efficacy of allogeneic umbilical cord red blood cell transfusion for children with severe anaemia in a Kenyan hospital: an open-label single-arm trial
Hassall, O. W. Thitiri, J. Fegan, G. Hamid, et al.
Lancet Haematol. 2015; 2:e101-7
-
2015
Predicting mortality in sick African children: the FEAST Paediatric Emergency Triage (PET) Score
George, E. C. Walker, A. S. Kiguli, S. Olupot-Olupot, et al.
BMC Med. 2015; 13:174
-
2014
Phase II trial of standard versus increased transfusion volume in Ugandan children with acute severe anemia
Olupot-Olupot, P. Engoru, C. Thompson, J. Nteziyaremye, et al.
BMC Med. 2014; 12:67
-
2014
Fluid management of shock in severe malnutrition: what is the evidence for current guidelines and what lessons have been learned from clinical studies and trials in other pediatric populations?
Obonyo, N. Maitland, K.
Food Nutr Bull. 2014; 35:S71-8
- 2014
-
2014
Strategies for efficient computation of the expected value of partial perfect information
Madan, J. Ades, A. E. Price, M. Maitland, et al.
Med Decis Making. 2014; 34:327-42
-
2014
Spleen volume and clinical disease manifestations of severe Plasmodium falciparum malaria in African children
Kotlyar, S. Nteziyaremye, J. Olupot-Olupot, P. Akech, et al.
Trans R Soc Trop Med Hyg. 2014; 108:283-9
- 2014
-
2014
WHO guidelines on fluid resuscitation in children: missing the FEAST data
Kiguli, S. Akech, S. O. Mtove, G. Opoka, et al.
BMJ. 2014; 348:f7003
-
2014
Four phases of intravenous fluid therapy: a conceptual model
Hoste, E. A. Maitland, K. Brudney, C. S. Mehta, et al.
Br J Anaesth. 2014; 113:740-7
-
2014
Invasive bacterial co-infection in African children with Plasmodium falciparum malaria: a systematic review
Church, J. Maitland, K.
BMC Med. 2014; 12:31
-
2013
Endotoxaemia is common in children with Plasmodium falciparum malaria
Olupot-Olupot, P. Urban, B. C. Jemutai, J. Nteziyaremye, et al.
BMC Infect Dis. 2013; 13:117
-
2013
Management of severe malaria: results from recent trials
Olupot-Olupot, P. Maitland, K.
Adv Exp Med Biol. 2013; 764:241-50
-
2013
'The words will pass with the blowing wind': staff and parent views of the deferred consent process, with prior assent, used in an emergency fluids trial in two African hospitals
Molyneux, S. Njue, M. Boga, M. Akello, et al.
PLoS One. 2013; 8:e54894
-
2013
Exploring mechanisms of excess mortality with early fluid resuscitation: insights from the FEAST trial
Maitland, K. George, E. C. Evans, J. A. Kiguli, et al.
BMC Med. 2013; 11:68
-
2012
Predicting the clinical outcome of severe falciparum malaria in african children: findings from a large randomized trial
von Seidlein, L. Olaosebikan, R. Hendriksen, I. C. Lee, et al.
Clin Infect Dis. 2012; 54:1080-90
-
2012
Diarrhoea complicating severe acute malnutrition in Kenyan children: a prospective descriptive study of risk factors and outcome
Talbert, A. Thuo, N. Karisa, J. Chesaro, et al.
PLoS One. 2012; 7:e38321
-
2012
Sequence variation does not confound the measurement of plasma PfHRP2 concentration in African children presenting with severe malaria
Ramutton, T. Hendriksen, I. C. Mwanga-Amumpaire, J. Mtove, et al.
Malar J. 2012; 11:276
-
2012
The FEAST trial of fluid bolus in African children with severe infection
Maitland, K. Babiker, A. Kiguli, S. Molyneux, et al.
Lancet. 2012; 379:613; author reply 613-4
-
2012
Diagnosing severe falciparum malaria in parasitaemic African children: a prospective evaluation of plasma PfHRP2 measurement
Hendriksen, I. C. Mwanga-Amumpaire, J. von Seidlein, L. Mtove, et al.
PLoS Med. 2012; 9:e1001297
-
2012
The microbiologic safety of umbilical cord blood transfusion for children with severe anemia in Mombasa, Kenya
Hassall, O. W. Thitiri, J. Fegan, G. Pole, et al.
Transfusion. 2012; 52:1542-51
-
2012
Tailoring management of severe and complicated malnutrition: more research is required first
Brent, B. Obonyo, N. Maitland, K.
Pathog Glob Health. 2012; 106:197-9
-
2012
External financial aid to blood transfusion services in sub-Saharan Africa: a need for reflection
Ala, F. Allain, J. P. Bates, I. Boukef, et al.
PLoS Med. 2012; 9:e1001309
-
2011
Dosing regimens of oral ciprofloxacin for children with severe malnutrition: a population pharmacokinetic study with Monte Carlo simulation
Thuo, N. Ungphakorn, W. Karisa, J. Muchohi, et al.
J Antimicrob Chemother. 2011; 66:2336-45
-
2011
Determination of ciprofloxacin in human plasma using high-performance liquid chromatography coupled with fluorescence detection: application to a population pharmacokinetics study in children with severe malnutrition
Muchohi, S. N. Thuo, N. Karisa, J. Muturi, et al.
J Chromatogr B Analyt Technol Biomed Life Sci. 2011; 879:146-52
-
2011
Excess child mortality after discharge from hospital in Kilifi, Kenya: a retrospective cohort analysis
Moisi, J. C. Gatakaa, H. Berkley, J. A. Maitland, et al.
Bull World Health Organ. 2011; 89:725-32, 732A
-
2011
Diagnostic performance of visible severe wasting for identifying severe acute malnutrition in children admitted to hospital in Kenya
Mogeni, P. Twahir, H. Bandika, V. Mwalekwa, et al.
Bull World Health Organ. 2011; 89:900-6
-
2011
Use of deferred consent for severely ill children in a multi-centre phase III trial
Maitland, K. Molyneux, S. Boga, M. Kiguli, et al.
Trials. 2011; 12:90
-
2011
Mortality after fluid bolus in African children with severe infection
Maitland, K. Kiguli, S. Opoka, R. O. Engoru, et al.
N Engl J Med. 2011; 364:2483-95
-
2011
Mortality after fluid bolus in African children with sepsis
Maitland, K Akech, S. Russell, B.
New England Journal of Medicine.. 2011; 365:1351-1353
- 2011
-
2011
Likely health outcomes for untreated acute febrile illness in the tropics in decision and economic models; a Delphi survey
Lubell, Y. Staedke, S. G. Greenwood, B. M. Kamya, et al.
PLoS One. 2011; 6:e17439
-
2011
Maternal perceptions of factors contributing to severe under-nutrition among children in a rural African setting
Abubakar, A. Holding, P. Mwangome, M. Maitland, et al.
Rural Remote Health. 2011; 11:1423
-
2010
Cardiac function and hemodynamics in Kenyan children with severe malaria
Yacoub, S. Lang, H. J. Shebbe, M. Timbwa, et al.
Crit Care Med. 2010; 38:940-5
-
2010
The prognostic value of dipstick urinalysis in children admitted to hospital with severe malnutrition
Thuo, N. Ohuma, E. Karisa, J. Talbert, et al.
Arch Dis Child. 2010; 95:422-6
-
2010
Changing trends in blood transfusion in children and neonates admitted in Kilifi District Hospital, Kenya
Pedro, R. Akech, S. Fegan, G. Maitland, et al.
Malar J. 2010; 9:307
-
2010
Hypoglycaemia in severe malaria, clinical associations and relationship to quinine dosage
Ogetii, G. N. Akech, S. Jemutai, J. Boga, et al.
BMC Infect Dis. 2010; 10:334
-
2010
Transfusions in resource poor settings
Maitland, K. Hassall, O. Bates, I.
Hunters Tropical Medicine. 2010
-
2010
Antimicrobials in children admitted to hospital in malaria endemic areas
Maitland, K.
BMJ. 2010; 340:c1818
-
2010
CISH and susceptibility to infectious diseases
Khor, C. C. Vannberg, F. O. Chapman, S. J. Guo, et al.
N Engl J Med. 2010; 362:2092-101
-
2010
Iron deficiency and acute seizures: results from children living in rural Kenya and a meta-analysis
Idro, R. Gwer, S. Williams, T. N. Otieno, et al.
PLoS One. 2010; 5:e14001
-
2010
The quality of stored umbilical cord and adult-donated whole blood in Mombasa, Kenya
Hassall, O. Maitland, K. Fegan, G. Thitiri, et al.
Transfusion. 2010; 50:611-6
-
2010
Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomised trial
Dondorp, A. M. Fanello, C. I. Hendriksen, I. C. Gomes, et al.
Lancet. 2010; 376:1647-57
-
2010
Phase II trial on the use of Dextran 70 or starch for supportive therapy in Kenyan children with severe malaria
Akech, S. O. Jemutai, J. Timbwa, M. Kivaya, et al.
Crit Care Med. 2010; 38:1630-6
-
2010
Choice of fluids for resuscitation in children with severe infection and shock: systematic review
Akech, S. Ledermann, H. Maitland, K.
BMJ. 2010; 341:c4416
-
2009
Hypothermia in children with severe malnutrition: low prevalence on the tropical coast of Kenya
Talbert, A. Atkinson, S. Karisa, J. Ignas, et al.
J Trop Pediatr. 2009; 55:413-6
-
2009
Characteristics and outcome of cardiopulmonary resuscitation in hospitalised African children
Olotu, A. Ndiritu, M. Ismael, M. Mohammed, et al.
Resuscitation. 2009; 80:69-72
-
2009
Emergency triage assessment for hypoxaemia in neonates and young children in a Kenyan hospital: an observational study
Mwaniki, M. K. Nokes, D. J. Ignas, J. Munywoki, et al.
Bull World Health Organ. 2009; 87:263-70
-
2009
Joint BAPEN and Nutrition Society Symposium on 'Feeding size 0: the science of starvation'. Severe malnutrition: therapeutic challenges and treatment of hypovolaemic shock
Maitland, K.
Proc Nutr Soc. 2009; 68:274-80
-
2009
Bacterial contamination of pediatric whole blood transfusions in a Kenyan hospital
Hassall, O. Maitland, K. Pole, L. Mwarumba, et al.
Transfusion. 2009; 49:2594-8
-
2009
HIV infection, malnutrition, and invasive bacterial infection among children with severe malaria
Berkley, J. A. Bejon, P. Mwangi, T. Gwer, et al.
Clin Infect Dis. 2009; 49:336-43
-
2008
Incidence and clinical characteristics of group A rotavirus infections among children admitted to hospital in Kilifi, Kenya
Nokes, D. J. Abwao, J. Pamba, A. Peenze, et al.
PLoS Med. 2008; 5:e153
-
2008
Haptoglobin HP2-2 genotype, alpha-thalassaemia and acute seizures in children living in a malaria-endemic area
Idro, R. Williams, T. N. Gwer, S. Uyoga, et al.
Epilepsy Res. 2008; 81:114-8
-
2008
The incidence, aetiology and outcome of acute seizures in children admitted to a rural Kenyan district hospital
Idro, R. Gwer, S. Kahindi, M. Gatakaa, et al.
BMC Pediatr. 2008; 8:5
-
2008
Case management of HIV-infected severely malnourished children: challenges in the area of highest prevalence
Heikens, G. T. Bunn, J. Amadi, B. Manary, et al.
Lancet. 2008; 371:1305-7
-
2008
The acceptability to women in Mombasa, Kenya, of the donation and transfusion of umbilical cord blood for severe anaemia in young children
Hassall, O. Ngina, L. Kongo, W. Othigo, et al.
Vox Sang. 2008; 94:125-31
-
2008
Fraction of all hospital admissions and deaths attributable to malnutrition among children in rural Kenya
Bejon, P. Mohammed, S. Mwangi, I. Atkinson, et al.
Am J Clin Nutr. 2008; 88:1626-31
-
2008
Survival and haematological recovery of children with severe malaria transfused in accordance to WHO guidelines in Kilifi, Kenya
Akech, S. O. Hassall, O. Pamba, A. Idro, et al.
Malar J. 2008; 7:256
-
2007
Population pharmacokinetics of a single daily intramuscular dose of gentamicin in children with severe malnutrition
Seaton, C. Ignas, J. Muchohi, S. Kokwaro, et al.
J Antimicrob Chemother. 2007; 59:681-9
-
2007
Phase III trials required to resolve clinical equipoise over optimal fluid management in children with severe malaria
Maitland, K. Akech, S. Gwer, S. Idro, et al.
PLoS Clin Trials. 2007; 2:e2
-
2007
Positive replication and linkage disequilibrium mapping of the chromosome 21q22.1 malaria susceptibility locus
Khor, C. C. Vannberg, F. O. Chapman, S. J. Walley, et al.
Genes Immun. 2007; 8:570-6
-
2007
A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis
Khor, C. C. Chapman, S. J. Vannberg, F. O. Dunne, et al.
Nat Genet. 2007; 39:523-8
-
2007
Burden, features, and outcome of neurological involvement in acute falciparum malaria in Kenyan children
Idro, R. Ndiritu, M. Ogutu, B. Mithwani, et al.
JAMA. 2007; 297:2232-40
-
2007
Defining childhood severe falciparum malaria for intervention studies
Bejon, P. Berkley, J. A. Mwangi, T. Ogada, et al.
PLoS Med. 2007; 4:e251
-
2006
Research priorities in the management of severe Plasmodium falciparum malaria in children
Idro, R. Aketch, S. Gwer, S. Newton, et al.
Ann Trop Med Parasitol. 2006; 100:95-108
-
2006
Are laboratory services coming of age in sub-Saharan Africa?
Bates, I. Maitland, K.
Clin Infect Dis. 2006; 42:383-4
-
2006
Volume expansion with albumin compared to gelofusine in children with severe malaria: results of a controlled trial
Akech, S. Gwer, S. Idro, R. Fegan, et al.
PLoS Clin Trials. 2006; 1:e21
-
2005
Both heterozygous and homozygous alpha+ thalassemias protect against severe and fatal Plasmodium falciparum malaria on the coast of Kenya
Williams, T. N. Wambua, S. Uyoga, S. Macharia, et al.
Blood. 2005; 106:368-71
-
2005
Progressive increase in antimicrobial resistance among invasive isolates of Haemophilus influenzae obtained from children admitted to a hospital in Kilifi, Kenya, from 1994 to 2002
Scott, J. A. Mwarumba, S. Ngetsa, C. Njenga, et al.
Antimicrob Agents Chemother. 2005; 49:3021-4
-
2005
Intravenous fluids--getting the balance right
Molyneux, E. M. Maitland, K.
N Engl J Med. 2005; 353:941-4
-
2005
Tropical infections: malaria and dengue.
Maitland, K. Wills, B.
Infectious Diseases in the Pediatric Intensive Care Unit.. 2005
-
2005
Perturbations in electrolyte levels in kenyan children with severe malaria complicated by acidosis
Maitland, K. Pamba, A. Fegan, G. Njuguna, et al.
Clin Infect Dis. 2005; 40:9-16
-
2005
Randomized trial of volume expansion with albumin or saline in children with severe malaria: preliminary evidence of albumin benefit
Maitland, K. Pamba, A. English, M. Peshu, et al.
Clin Infect Dis. 2005; 40:538-45
-
2005
Pre-transfusion management of children with severe malarial anaemia: a randomised controlled trial of intravascular volume expansion
Maitland, K. Pamba, A. English, M. Peshu, et al.
Br J Haematol. 2005; 128:393-400
-
2005
Acidosis of severe falciparum malaria: heading for a shock?
Maitland, K. Newton, C. R.
Trends Parasitol. 2005; 21:11-6
-
2005
Volume status in severe malaria: no evidence provided for the degree of filling of the intravascular compartment
Maitland, K. Newton, C. Marsh, K. Levin, et al.
PLoS Med. 2005; 2:e27; author reply e32
-
2005
Management of severe malaria in children: proposed guidelines for the United Kingdom
Maitland, K. Nadel, S. Pollard, A. J. Williams, et al.
BMJ. 2005; 331:337-43
- 2005
-
2005
Decorticate, decerebrate and opisthotonic posturing and seizures in Kenyan children with cerebral malaria
Idro, R. Otieno, G. White, S. Kahindi, et al.
Malar J. 2005; 4:57
-
2005
Use of clinical syndromes to target antibiotic prescribing in seriously ill children in malaria endemic area: observational study
Berkley, J. A. Maitland, K. Mwangi, I. Ngetsa, et al.
BMJ. 2005; 330:995
-
2005
Bacteremia among children admitted to a rural hospital in Kenya
Berkley, J. A. Lowe, B. S. Mwangi, I. Williams, et al.
N Engl J Med. 2005; 352:39-47
-
2005
Assessment of severe malnutrition among hospitalized children in rural Kenya: comparison of weight for height and mid upper arm circumference
Berkley, J. Mwangi, I. Griffiths, K. Ahmed, et al.
JAMA. 2005; 294:591-7
-
2005
Invasive Gram-negative bacilli are frequently resistant to standard antibiotics for children admitted to hospital in Kilifi, Kenya
Bejon, P. Mwangi, I. Ngetsa, C. Mwarumba, et al.
J Antimicrob Chemother. 2005; 56:232-5
-
2004
Capillary refill: prognostic value in Kenyan children
Pamba, A. Maitland, K.
Arch Dis Child. 2004; 89:950-5
-
2004
Fluid management of severe falciparum malaria in African children
Pamba, A. Maitland, K.
Trop Doct. 2004; 34:67-70
-
2004
Are bedside features of shock reproducible between different observers?
Otieno, H. Were, E. Ahmed, I. Charo, et al.
Arch Dis Child. 2004; 89:977-9
-
2004
Salicylate poisoning in children: report of three cases
Musumba, C. O. Pamba, A. O. Sasi, P. A. English, et al.
East Afr Med J. 2004; 81:159-63
-
2004
Hypokalemia in children with severe falciparum malaria
Maitland, K. Pamba, A. Newton, C. R. Lowe, et al.
Pediatr Crit Care Med. 2004; 5:81-5
-
2004
Intravenous fluids for seriously ill children
Maitland, K. Newton, C. English, M.
Lancet. 2004; 363:242-3
- 2004
- 2004
-
2004
Falciparum malaria: current therapeutic challenges
Maitland, K. Makanga, M. Williams, T. N.
Curr Opin Infect Dis. 2004; 17:405-12
-
2004
HLA class-I and class-II allele frequencies and two-locus haplotypes in Melanesians of Vanuatu and New Caledonia
Maitland, K. Bunce, M. Harding, R. M. Barnardo, et al.
Tissue Antigens. 2004; 64:678-86
-
2004
Mortality among Kenyan children admitted to a rural district hospital on weekends as compared with weekdays
Berkley, J. A. Brent, A. Mwangi, I. English, et al.
Pediatrics. 2004; 114:1737-8; author reply 1738
-
2003
Response to volume resuscitation in children with severe malaria
Maitland, K. Pamba, A. Newton, C. R. Levin, et al.
Pediatr Crit Care Med. 2003; 4:426-31
- 2003
-
2003
Severe P. falciparum malaria in Kenyan children: evidence for hypovolaemia
Maitland, K. Levin, M. English, M. Mithwani, et al.
QJM. 2003; 96:427-34
- 2003