My responsibilities include providing leadership and coordination for clinical research and trials as well as monitoring, project management, database support and sponsorship for KWTRP investigator-led trials. I trained as a Paediatrician in Oxford and first started working in clinical trials over 15 years ago. My research career started in Oxford followed by a 6-month Wellcome Trust visiting fellowship to the KEMRI-Wellcome Trust programme in 2006 and a return to Kenya in 2016. My work in Kathmandu, Nepal and Oxfordshire focused on the population biology and vaccinology of Streptococcus pneumoniae in pre-school children. With a team of Nepali scientists, we conducted a vaccine trial in infants which informed and led to the introduction of the 10-valent pneumococcal conjugate vaccination schedule in Nepalese infants.