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Researcher
Dr. James Nyagwange
Post-Doc
KEMRI | Wellcome Trust
Publications (30)
A complete list of publications by Dr. James Nyagwange. Use the filters to refine by year, journal or keyword.
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2026
Comparison of capillary microsampling and venous blood for multi-pathogen serosurveillance
Ombati, R. Kimani, M. Akech, D. Kutima, et al.
Sci Rep. 2026
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2026
A natural experiment in Kenya reveals durable immunosuppressive effects of early childhood malaria: a longitudinal cohort study
Safari, M. S. Makori, T. O. Gicheru, E. T. Mburu, et al.
Elife. 2026; 14
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2026
Longitudinal evidence of differential pertussis antibody durability following natural infection among vaccinated children living in contrasting malaria transmission settings in coastal Kenya
Safari, M. S. Gicheru, E. T. Mburu, M. W. Makori, et al.
Vaccine. 2026; 88:128837
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2026
Heart-nosed bat alphacoronaviruses use human CEACAM6 to enter cells
Gallo, G. Di Nardo, A. Lugano, D. Roberts, et al.
Nature. 2026; 653:180-189
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2026
Longitudinal Epidemiology and Variant Dynamics of SARS-CoV-2 in Coastal Kenya (2020-2025): Clinical Features and Wave Patterns
Lambisia, A. W. Nyiro, J. Githinji, G. Katama, et al.
Open Forum Infect Dis. 2026; 13:ofag084
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2025
Assessing the Impact of SARS-CoV-2 Spike Mutations on Antibody Binding: A Comparative Assessment of the Wuhan and JN.1 Variants' Full-Length Spikes in a Multiplex Luminex Assay
Waweru, G. Nyakundi, R. Kutima, B. Owuor, et al.
Viruses. 2025; 17
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2025
Genomic and clinical epidemiology of SARS-CoV-2 in coastal Kenya: insights into variant circulation, reinfection, and multiple lineage importations during a post-pandemic wave
Lambisia, A. W. Katama, E. N. Moraa, E. Mwita, et al.
BMC Glob Public Health. 2025; 3:80
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2023
Kinetics of naturally induced binding and neutralising anti-SARS-CoV-2 antibody levels and potencies among SARS-CoV-2 infected Kenyans with diverse grades of COVID-19 severity: an observational study
Kimotho, J. Sein, Y. Sayed, S. Shah, et al.
Wellcome Open Res. 2023; 8:350
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2024
Profile: The Kenya Multi-Site Serosurveillance (KEMIS) collaboration
Kagucia, E. W. Voller, S. Ziraba, A. K. Bigogo, et al.
Gates Open Res. 2024; 8:60
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2024
Evaluation of population immunity against SARS-CoV-2 variants, EG.5.1, FY.4, BA.2.86, JN.1, JN.1.4, and KP.3.1.1 using samples from two health demographic surveillance systems in Kenya
Lugano, D. Kutima, B. Kimani, M. Sigilai, et al.
BMC Infect Dis. 2024; 24:1474
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2024
Comparative performance of the InBios SCoV-2 Detect (TM) IgG ELISA and the in-house KWTRP ELISA in detecting SARS-CoV-2 spike IgG antibodies in Kenyan populations
Kutima, B. Kagucia, E. W. Mwai, K. Kimani, et al.
Wellcome Open Res. 2024; 9:349
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2023
A Customizable Suite of Methods to Sequence and Annotate Cattle Antibodies
Ramirez Valdez, K. Nzau, B. Dorey-Robinson, D. Jarman, et al.
Vaccines (Basel). 2023; 11
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2023
Serum immunoglobulin G and mucosal immunoglobulin A antibodies from prepandemic samples collected in Kilifi, Kenya, neutralize SARS-CoV-2 in vitro
Nyagwange, J. Kutima, B. Mwai, K. Karanja, et al.
Int J Infect Dis. 2023; 127:11-16
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2023
SARS-CoV-2 seroprevalence and implications for population immunity: Evidence from two Health and Demographic Surveillance System sites in Kenya, February-December 2022
Kagucia, E. W. Ziraba, A. K. Nyagwange, J. Kutima, et al.
Influenza Other Respir Viruses. 2023; 17:e13173
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2023
Safety and immunogenicity of ChAdOx1 nCoV-19 (AZD1222) vaccine in adults in Kenya: a phase 1/2 single-blind, randomised controlled trial
Hamaluba, M. Sang, S. Orindi, B. Njau, et al.
Wellcome Open Res. 2023; 8:182
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2023
Symptom prevalence and secondary attack rate of SARS-CoV-2 in rural Kenyan households: A prospective cohort study
Gallagher, K. E. Nyiro, J. Agoti, C. N. Maitha, et al.
Influenza Other Respir Viruses. 2023; 17:e13185
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2022
Epidemiology of COVID-19 infections on routine polymerase chain reaction (PCR) and serology testing in Coastal Kenya
Nyagwange, J. Ndwiga, L. Muteru, K. Wamae, et al.
Wellcome Open Res. 2022; 7:69
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2022
Comparative performance of WANTAI ELISA for total immunoglobulin to receptor binding protein and an ELISA for IgG to spike protein in detecting SARS-CoV-2 antibodies in Kenyan populations
Nyagwange, J. Kutima, B. Mwai, K. Karanja, et al.
J Clin Virol. 2022; 146:105061
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2022
Sero-surveillance for IgG to SARS-CoV-2 at antenatal care clinics in three Kenyan referral hospitals: Repeated cross-sectional surveys 2020-21
Lucinde, R. K. Mugo, D. Bottomley, C. Karani, et al.
PLoS One. 2022; 17:e0265478
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2022
Seroprevalence of Antibodies to Severe Acute Respiratory Syndrome Coronavirus 2 Among Healthcare Workers in Kenya
Etyang, A. O. Lucinde, R. Karanja, H. Kalu, et al.
Clin Infect Dis. 2022; 74:288-293
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2022
SARS-CoV-2 seroprevalence in three Kenyan health and demographic surveillance sites, December 2020-May 2021
Etyang, A. O. Adetifa, I. Omore, R. Misore, et al.
PLOS Glob Public Health. 2022; 2:e0000883
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2021
Prevalence of anti-SARS-CoV-2 IgG antibodies among Kenyan blood donors between June and August 2021.
Uyoga, S. Otiende, M. Adetifa, I. M. O. Karanja, et al.
1st International Conference on Public Health in Africa (CPHIA). 2021
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2021
Seroprevalence of anti-SARS-CoV-2 IgG antibodies in Kenyan blood donors
Uyoga, S. Adetifa, I. M. O. Karanja, H. K. Nyagwange, et al.
Science. 2021; 371:79-82
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2021
Comparative performance of WANTAI ELISA for total immunoglobulin to receptor binding protein and an ELISA for IgG to spike protein in detecting SARS-CoV-2 antibodies in Kenyan populations.
Nyagwange, J. Kutima, B. Mwai, K. Karanja, et al.
1st International Conference on Public Health in Africa (CPHIA). 2021
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2021
Anti-Severe Acute Respiratory Syndrome Coronavirus 2 Immunoglobulin G Antibody Seroprevalence Among Truck Drivers and Assistants in Kenya
Kagucia, E. W. Gitonga, J. N. Kalu, C. Ochomo, et al.
Open Forum Infect Dis. 2021; 8:ofab314
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2021
High anti-SARS-CoV-2 IgG antibody seroprevalence among long-distance trucking crews in Kenya within one year of the COVID-19 pandemic.
Kagucia, E. W. Gitonga, J. N. Kalu, C. Kuya, et al.
1st International Conference on Public Health in Africa (CPHIA). 2021
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2021
Serosurveillance for SARS-CoV-2 Antibodies in a cohort of Health Care Workers in Kenya.
Etyang, A. O. Lucinde, R. Gitonga, J. N. Kalu, et al.
1st International Conference on Public Health in Africa (CPHIA). 2021
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2021
COVID-19 transmission dynamics underlying epidemic waves in Kenya
Brand, S. P. C. Ojal, J. Aziza, R. Were, et al.
Science. 2021; 374:989-994
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2021
Quantifying previous SARS-CoV-2 infection through mixture modelling of antibody levels
Bottomley, C. Otiende, M. Uyoga, S. Gallagher, et al.
Nat Commun. 2021; 12:6196
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2021
Temporal trends of SARS-CoV-2 seroprevalence during the first wave of the COVID-19 epidemic in Kenya
Adetifa, I. M. O. Uyoga, S. Gitonga, J. N. Mugo, et al.
Nat Commun. 2021; 12:3966