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Principal Investigator
Dr Eunice Nduati
Principal Investigator
KEMRI | Wellcome Trust
Publications (23)
A complete list of publications by Dr Eunice Nduati. Use the filters to refine by year, journal or keyword.
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2025
Unique genetic signatures in HIV-1 subtype A1 and A1D recombinant envelope glycoprotein distinguish contemporary transmitted/founder viruses from historical strains in East Africa
Kato, F. Kapaata, A. Galiwango, R. Nakyanzi, et al.
Front Microbiol. 2025; 16:1632581
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2025
Safety and broad immunogenicity of HIVconsvX conserved mosaic candidate T-cell vaccines vectored by ChAdOx1 and MVA in HIV-CORE 006: a double-blind, randomised, placebo-controlled phase 1 trial in healthy adults living without HIV-1 in eastern and southern Africa
Chanda, C. Kibengo, F. Mutua, M. Ogada, et al.
Lancet Microbe. 2025; 6:101041
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2025
Validation of high-throughput oxford nanopore technology for HIV-1 transmitted/founder virus identification
Byamukama, D. Ndekezi, C. Omara, D. Nakyanzi, et al.
Int J Infect Dis. 2025; 161:108138
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2025
Advancing the course of HIV genomics research in Africa
Agamah, F. E. Arbuthnot, P. Tindana, P. Munung, et al.
BMJ Glob Health. 2025; 10
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2024
Profiling IgG and IgA antibody responses during vaccination and infection in a high-risk gonorrhoea population
Stejskal, L. Thistlethwaite, A. Ramirez-Bencomo, F. Rashmi, et al.
Nat Commun. 2024; 15:6712
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2024
Evaluation of population immunity against SARS-CoV-2 variants, EG.5.1, FY.4, BA.2.86, JN.1, JN.1.4, and KP.3.1.1 using samples from two health demographic surveillance systems in Kenya
Lugano, D. Kutima, B. Kimani, M. Sigilai, et al.
BMC Infect Dis. 2024; 24:1474
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2023
Exposure to common infections may shape basal immunity and potentially HIV-1 acquisition amongst a high-risk population in Coastal Kenya
Fwambah, L. Andisi, C. Streatfield, C. Bromell, et al.
Front Immunol. 2023; 14:1283559
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2023
Serum immunoglobulin G and mucosal immunoglobulin A antibodies from prepandemic samples collected in Kilifi, Kenya, neutralize SARS-CoV-2 in vitro
Nyagwange, J. Kutima, B. Mwai, K. Karanja, et al.
Int J Infect Dis. 2023; 127:11-16
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2022
Assessment of a diverse panel of transmitted/founder HIV-1 infectious molecular clones in a luciferase based CD8 T-cell mediated viral inhibition assay
Fernandez, N. Hayes, P. Makinde, J. Hare, et al.
Front Immunol. 2022; 13:1029029
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2021
Atypical B cells are part of an alternative lineage of B cells that participates in responses to vaccination and infection in humans
Sutton, H. J. Aye, R. Idris, A. H. Vistein, et al.
Cell Rep. 2021; 34:108684
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2019
Symptom-based Scoring for Acute Human Immunodeficiency Virus
Sanders, E. J. Kigoro, A. Thiong'o, A. Nduati, et al.
Clin Infect Dis. 2019; 69:736-737
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2017
Cytomegalovirus viraemia is associated with poor growth and T-cell activation with an increased burden in HIV-exposed uninfected infants
Garcia-Knight, M. A. Nduati, E. Hassan, A. S. Nkumama, et al.
AIDS. 2017; 31:1809-1818
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2015
Altered Memory T-Cell Responses to Bacillus Calmette-Guerin and Tetanus Toxoid Vaccination and Altered Cytokine Responses to Polyclonal Stimulation in HIV-Exposed Uninfected Kenyan Infants
Garcia-Knight, M. A. Nduati, E. Hassan, A. S. Gambo, et al.
PLoS One. 2015; 10:e0143043
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2014
HIV-exposed uninfected children: a growing population with a vulnerable immune system?
Afran, L. Garcia Knight, M. Nduati, E. Urban, et al.
Clin Exp Immunol. 2014; 176:11-22
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2011
The plasma concentration of the B cell activating factor is increased in children with acute malaria
Nduati, E. Gwela, A. Karanja, H. Mugyenyi, et al.
J Infect Dis. 2011; 204:962-70
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2008
Effect of folate derivatives on the activity of antifolate drugs used against malaria and cancer
Nduati, E. Diriye, A. Ommeh, S. Mwai, et al.
Parasitol Res. 2008; 102:1227-34
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2005
Why has the dihydrofolate reductase 164 mutation not consistently been found in Africa yet?
Nzila, A. Ochong, E. Nduati, E. Gilbert, et al.
Trans R Soc Trop Med Hyg. 2005; 99:341-6
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2005
2,4-diaminopteridine-based compounds as precursors for de novo synthesis of antifolates: a novel class of antimalarials
Nduati, E. Hunt, S. Kamau, E. M. Nzila, et al.
Antimicrob Agents Chemother. 2005; 49:3652-7
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2004
In vitro activities of 2,4-diaminoquinazoline and 2,4-diaminopteridine derivatives against Plasmodium falciparum
Ommeh, S. Nduati, E. Mberu, E. Kokwaro, et al.
Antimicrob Agents Chemother. 2004; 48:3711-4
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2002
Genetic diversity of Plasmodium falciparum parasites from Kenya is not affected by antifolate drug selection
Nzila, A. M. Mberu, E. K. Nduati, E. Ross, et al.
Int J Parasitol. 2002; 32:1469-76
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2002
Plasmodium falciparum: in vitro activity of sulfadoxine and dapsone in field isolates from Kenya: point mutations in dihydropteroate synthase may not be the only determinants in sulfa resistance
Mberu, E. K. Nzila, A. M. Nduati, E. Ross, et al.
Exp Parasitol. 2002; 101:90-6
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2001
Chlorproguanil-dapsone for treatment of drug-resistant falciparum malaria in Tanzania
Mutabingwa, T. Nzila, A. Mberu, E. Nduati, et al.
Lancet. 2001; 358:1218-23
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2000
Molecular evidence of greater selective pressure for drug resistance exerted by the long-acting antifolate Pyrimethamine/Sulfadoxine compared with the shorter-acting chlorproguanil/dapsone on Kenyan Plasmodium falciparum
Nzila, A. M. Nduati, E. Mberu, E. K. Hopkins Sibley, et al.
J Infect Dis. 2000; 181:2023-8