A complete list of publications by Prof. Melissa Kapulu. Use the filters to refine by year, journal or keyword.

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1. 2026
   Baseline Treg frequency, Treg-associated immune checkpoint responses, and plasma IL-10 responses during controlled human malaria infection in semi-immune Kenyan adults: a secondary analysis of the CHMI-SIKA Study

   Kimenyi, K. M. Morter, R. Nyabundi, D. Orindi, et al.

   Lancet Microbe. 2026; 101375

   View abstract DOI PubMed
2. 2026
   Widespread variants of the highly polymorphic Plasmodium falciparum vaccine candidate antigen MSP2 across Sub-Saharan Africa

   Zerebinski, J. Broumou, I. Kimenyi, K. M. Aklillu, et al.

   J Infect Dis. 2026

   View abstract DOI PubMed
3. 2026
   Baseline Treg frequency, Treg-associated immune checkpoint responses, and plasma IL-10 responses during controlled human malaria infection in semi-immune Kenyan adults: a secondary analysis of the CHMI-SIKA Study

   Kimenyi, K. M. Morter, R. Nyabundi, D. Orindi, et al.

   Lancet Microbe. 2026; 101375

   View abstract DOI PubMed
4. 2026
   Widespread variants of the highly polymorphic Plasmodium falciparum vaccine candidate antigen MSP2 across Sub-Saharan Africa

   Zerebinski, J. Broumou, I. Kimenyi, K. M. Aklillu, et al.

   J Infect Dis. 2026

   View abstract DOI PubMed
5. 2025
   Protein-specific immune response elicited by the Shigella sonnei 1790GAHB GMMA-based candidate vaccine in adults with varying exposure to Shigella

   Randall, A. Z. Conti, V. Nakakana, U. Liang, et al.

   mSphere. 2025; 10:e0105724

   View abstract DOI PubMed
6. 2025
   Reversible host cell surface remodelling limits immune recognition and maximizes survival of Plasmodium falciparum gametocytes

   Ngotho, P. Dantzler Press, K. Peedell, M. Muasya, et al.

   PLoS Pathog. 2025; 21:e1013110

   View abstract DOI PubMed
7. 2025
   R21/Matrix-M malaria vaccine drives diverse immune responses in pre-exposed adults: insights from a phase IIb controlled human malaria infection trial

   Kibwana, E. Bundi, C. Kimani, D. Nyamako, et al.

   Front Immunol. 2025; 16:1620365

   View abstract DOI PubMed
8. 2024
   Reversible host cell surface remodelling limits immune recognition and maximizes transmission of Plasmodium falciparum gametocytes

   Ngotho, P. Press, K. D. Peedell, M. Muasya, et al.

   bioRxiv. 2024

   View abstract DOI PubMed
9. 2024
   Controlled Human Malaria Infection Studies in Africa-Past, Present, and Future

   Kibwana, E. Kapulu, M. Bejon, P.

   Curr Top Microbiol Immunol. 2024; 445:337-365

   View abstract DOI PubMed
10. 2024
    Fourth Controlled Human Infection Model (CHIM) meeting - CHIMs in endemic countries, May 22-23, 2023

    Kapulu, M. Manda-Taylor, L. Balasingam, S. Means, et al.

    Biologicals. 2024; 85:101747

    View abstract DOI PubMed
11. 2024
    Fourth Controlled Human Infection Model (CHIM) meeting, CHIM regulatory issues, May 24, 2023

    Cavaleri, M. Kaslow, D. Boateng, E. Chen, et al.

    Biologicals. 2024; 85:101745

    View abstract DOI PubMed
12. 2023
    Safety and immunogenicity of varied doses of R21/Matrix-M vaccine at three years follow-up: A phase 1b age de-escalation, dose-escalation trial in adults, children, and infants in Kilifi-Kenya

    Sang, S. Datoo, M. S. Otieno, E. Muiruri, et al.

    Wellcome Open Res. 2023; 8:450

    View abstract DOI PubMed
13. 2023
    Sporozoite immunization: innovative translational science to support the fight against malaria

    Richie, T. L. Church, L. W. P. Murshedkar, T. Billingsley, et al.

    Expert Rev Vaccines. 2023; 22:964-1007

    View abstract DOI PubMed
14. 2023
    Where do those data go? Reuse of screening results from clinical trials to estimate population prevalence of HBV infection in adults in Kilifi, Kenya

    Downs, L. O. Campbell, C. Abouyannis, M. Otiende, et al.

    J Virus Erad. 2023; 9:100355

    View abstract DOI PubMed
15. 2022
    Ethics review of COVID-19 human challenge studies: A joint HRA/WHO workshop

    Williams, E. Craig, K. Chiu, C. Davies, et al.

    Vaccine. 2022; 40:3484-3489

    View abstract DOI PubMed
16. 2022
    Ethical considerations around volunteer payments in a malaria human infection study in Kenya: an embedded empirical ethics study

    Chi, P. C. Owino, E. A. Jao, I. Bejon, et al.

    BMC Med Ethics. 2022; 23:46

    View abstract DOI PubMed
17. 2021
    Equity for excellence in academic institutions: a manifesto for change

    Wedekind, L. Noe, A. Mokaya, J. Tamandjou, et al.

    Wellcome Open Res. 2021; 6:142

    View abstract DOI PubMed
18. 2021
    Engagement of ethics and regulatory authorities on human infection studies: Proceedings of an engagement workshop in Zambia

    Kunda-Ng'andu, E. M. Simuyandi, M. Kapulu, M. Chirwa-Chobe, et al.

    Wellcome Open Res. 2021; 6:31

    View abstract DOI PubMed
19. 2021
    Key criteria for the ethical acceptability of COVID-19 human challenge studies: Report of a WHO Working Group

    Jamrozik, E. Littler, K. Bull, S. Emerson, et al.

    Vaccine. 2021; 39:633-640

    View abstract DOI PubMed
20. 2021
    Understanding the benefits and burdens associated with a malaria human infection study in Kenya: experiences of study volunteers and other stakeholders

    Chi, P. C. Owino, E. A. Jao, I. Olewe, et al.

    Trials. 2021; 22:494

    View abstract DOI PubMed
21. 2020
    Deliberately infecting healthy volunteers with malaria parasites: Perceptions and experiences of participants and other stakeholders in a Kenyan-based malaria infection study

    Jao, I. Marsh, V. Che Chi, P. Kapulu, et al.

    Bioethics. 2020; 34:819-832

    View abstract DOI PubMed
22. 2019
    Author Correction: The temporal dynamics and infectiousness of subpatent Plasmodium falciparum infections in relation to parasite density

    Slater, H. C. Ross, A. Felger, I. Hofmann, et al.

    Nat Commun. 2019; 10:2644

    View abstract DOI PubMed
23. 2019
    The temporal dynamics and infectiousness of subpatent Plasmodium falciparum infections in relation to parasite density

    Slater, H. C. Ross, A. Felger, I. Hofmann, et al.

    Nat Commun. 2019; 10:1433

    View abstract DOI PubMed
24. 2019
    Correction to: Detection of Plasmodium falciparum infected Anopheles gambiae using near-infrared spectroscopy

    Maia, M. F. Kapulu, M. Muthui, M. Wagah, et al.

    Malar J. 2019; 18:137

    View abstract DOI PubMed
25. 2019
    Detection of Plasmodium falciparum infected Anopheles gambiae using near-infrared spectroscopy

    Maia, M. F. Kapulu, M. Muthui, M. Wagah, et al.

    Malar J. 2019; 18:85

    View abstract DOI PubMed
26. 2018
    Single low-dose primaquine for blocking transmission of Plasmodium falciparum malaria - a proposed model-derived age-based regimen for sub-Saharan Africa

    Taylor, W. R. Naw, H. K. Maitland, K. Williams, et al.

    BMC Med. 2018; 16:11

    View abstract DOI PubMed
27. 2018
    Ethical and scientific considerations on the establishment of a controlled human infection model for schistosomiasis in Uganda: report of a stakeholders' meeting held in Entebbe, Uganda

    Elliott, A. M. Roestenberg, M. Wajja, A. Opio, et al.

    AAS Open Res. 2018; 1:2

    View abstract DOI PubMed
28. 2017
    Detecting Malaria Hotspots: A Comparison of Rapid Diagnostic Test, Microscopy, and Polymerase Chain Reaction

    Mogeni, P. Williams, T. N. Omedo, I. Kimani, et al.

    J Infect Dis. 2017; 216:1091-1098

    View abstract DOI PubMed