Ifedayo is a paediatrician and infectious diseases epidemiologist and the overarching aim of his research is to provide evidence for vaccine policy in low and middle-income countries especially those in Africa. He works full-time at the KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya where he holds a position of Clinical Epidemiologist in the Epidemiology and Demography Department. He is also an Associate Professor of Infectious Disease Epidemiology at the London School of Hygiene and Tropical Medicine. Prior to his arrival at the programme, he worked for a decade at the United Kingdom's Medical Research Council Unit, The Gambia where he led clinical and field activities for the Tuberculosis (TB) epidemiology research including the TB case contact platform. His research interests there were delivery of TB diagnostics and care, assessment of novel diagnostics for TB infection and disease including biomarkers for disease and protection, and systematic reviews. In his last MRC role, he was the principal investigator on a Â£2.6million TB Epidemiology projects portfolio that included a nationwide TB prevalence survey and a community randomised trial to assess the impact of an enhanced TB case finding strategy on TB notification.
His research interest includes evaluations of vaccine effectiveness and is currently work on pneumococcal conjugate vaccine impact studies in Kenya and Nigeria, and rotavirus vaccine impact studies in Kenya. He is specifically interested in the scientific basis for managing pneumococcal conjugate vaccine programmes in Africa with only pneumococcal carriage data, and in vaccine seroepidemiology including the scientific basis for methods of estimating vaccination coverage and population immunity.