I am an alumni of Kenyatta University where I studied Biochemistry (BSc) and Biotechnology (MSc). For my MSc thesis, I investigated whether malaria transmission reduction following introduction of bednets affected the genetic diversity of the 19 kDa C terminal portion of the merozoite surface protein 1 present in the malaria parasite, Plasmodium falciparum, at the KEMRI-CDC programme in Kisumu, Kenya. I subsequently completed a PhD in Biochemistry in 2013 from Rhodes University in South Africa where I characterized several heat shock proteins (molecular chaperones) in P. falciparum.
At the KEMRI-Wellcome Trust Programme, we have an UltiMate™ 3000 Rapid Separation HPLC system coupled to a Q Exactive Mass Spectrometer. I have adopted this system for Proteomics- the largescale identification and relative quantification of proteins in a biological specimen. My current work focuses on Biomarker discovery, which for proteomics means identifying a small set of proteins whose expression pattern can separate two or more groups of specimens and can be used for efficient classification of unknown specimens. Ultimately, a good biomarker can be developed into a point-of-care test for diagnosis or prognosis. I am interested in identifying such biomarkers that will translate into better clinical management of sick children.