Biography

Charles was born in Kenya, qualified in Cape Town, South Africa, with postgraduate training in Paediatrics in Manchester and London, United Kingdom. As a lecturer at University of Oxford, he returned to Kilifi Kenya in 1989, to help set up an unit to study severe malaria in African children. Thereafter he spent 2 years as a Post-doctoral fellow at Johns Hopkins, USA; studying mechanisms of brain damage in central nervous system infections. He completed his training in Paediatric Neurology at Great Ormond Street Hospital, UK. In 1998 he was awarded a Wellcome Trust Senior Clinical Fellowship at University College London, to return to Kilifi, to study CNS infections in children. He has published on a wide variety of subjects concerning sick children in tropical countries. In 2011 he took up a professorship in Psychiatry at the University of Oxford to concentrate of neurological and mental illness disorders in children living in Africa.

Current Work

He conducts research on CNS infections in children; epidemiological studies of epilepsy and neurological impairment; tetanus, jaundice and sepsis in neonates. At present he is conducting studies of Autism and Epilepsy in Africa and working on sickle cell disease in Tanzania.

Collaborations

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Publications

Association between psychosis and substance use in Kenya. Findings from the NeuroGAP-Psychosis study.
Nguata, M., Orwa, J., Kigen, G., Kamaru, E., Emonyi, W., Kariuki, S., Newton, C., Ongeri, L., Mwende, R., Gichuru, S., Atwoli, L.
Front Psychiatry, (2024). 15:1301976

Utility of the 3Di short version in the identification and diagnosis of autism in children at the Kenyan coast.
Kipkemoi, P., Kariuki, S. M., Gona, J., Mwangi, F. W., Kombe, M., Kipkoech, C., Murimi, P., Mandy, W., Warrington, R., Skuse, D., Newton, C. R. J. C., Abubakar, A.
Front Psychiatry, (2024). 15:1234929

Prevalence and Factors Associated With Frailty Among Older Adults Living With HIV Compared to Their Uninfected Peers From the Kenyan Coast.
Mwangala, P. N., Nasambu, C., Wagner, R. G., Newton, C. R., Abubakar, A.
Int J Public Health, (2024). 69:1606284

Psychometric Properties of the Mini International Neuropsychiatric Interview (MINI) Psychosis Module: A Sub-Saharan Africa Cross Country Comparison - CORRIGENDUM.
Korte, K. J., Jaguga, F., Kim, H. H., Stroud, R. E., Stevenson, A., Akena, D., Atwoli, L., Gichuru, S., James, R., Kwobah, E., Kariuki, S. M., Kyebuzibwa, J., Mwema, R. M., Newton, Crjc, Zingela, Z., Stein, D. J., Alemayehu, M., Teferra, S., Koenen, K. C., Gelaye, B.
Psychol Med, (2024). 54:436

Magnetic Resonance Imaging Findings in Kenyans and South Africans with Active Convulsive Epilepsy: An Observational Study.
Kariuki, S. M., Wagner, R. G., Gunny, R., D'Arco, F., Kombe, M., Ngugi, A. K., White, S., Odhiambo, R., Cross, J. H., Sander, J. W., Newton, Crjc
Epilepsia, (2023). 65:165-176

Effectiveness of participatory video in lowering stigma against people with mental, neurological and substance use disorders in Kenya.
Bitta, M. A., Baariu, J., Grassi, S., Kariuki, S. M., Lennox, B., Newton, Crjc
BJPsych Open, (2023). 9:e215

Neurocognitive outcomes of children exposed to and living with HIV aged 3-5 years in Kilifi, Kenya.
Chongwo, E. J., Wedderburn, C. J., Nyongesa, M. K., Sigilai, A., Mwangi, P., Thoya, J., Odhiambo, R., Ngombo, K., Kabunda, B., Newton, C. R., Abubakar, A.
Front Reprod Health, (2023). 5:1193183

Prostration and the prognosis of death in African children with severe malaria.
Agnandji, S. T., Recker, M., Mordm�ller, B., Gl�ckner, S., Adegnika, A. A., Lell, B., Otieno, L., Otieno, W., Owusu-Agyei, S., Asante, K. P., Agbenyega, T., Ansong, D., Macete, E., Aide, P., Sorgho, H., Tinto, H., Mturi, N., Lusingu, J. P. A., Gesase, S., Hoffman, I., Masoud, N. S., Newton, C. R., Bojang, K., Krause, G., Kremsner, P. G.
Int J Infect Dis, (2023). 134:240-247

Phenotype and genetic analysis of data collected within the first year of NeuroDev.
Kipkemoi, P., Kim, H. A., Christ, B., O'Heir, E., Allen, J., Austin-Tse, C., Baxter, S., Brand, H., Bryant, S., Buser, N., de Menil, V., Eastman, E., Murugasen, S., Galvin, A., Kombe, M., Ngombo, A., Mkubwa, B., Mwangi, P., Kipkoech, C., Lovgren, A., MacArthur, D. G., Melly, B., Mwangasha, K., Martin, A., Nkambule, L. L., Sanchis-Juan, A., Singer-Berk, M., Talkowski, M. E., VanNoy, G., van der Merwe, C., Newton, C., O'Donnell-Luria, A., Abubakar, A., Donald, K. A., Robinson, E. B.
Neuron, (2023). S0896-6273:00470-1

Prostration and the prognosis of death in African children with severe malaria.
Agnandji, S. T., Recker, M., Mordmüller, B., Glöckner, S., Adegnika, A. A., Lell, B., Otieno, L., Otieno, W., Owusu-Agyei, S., Asante, K. P., Agbenyega, T., Ansong, D., Macete, E., Aide, P., Sorgho, H., Tinto, H., Mturi, N., Lusingu, J. P. A., Gesase, S., Hoffman, I., Masoud, N. S., Newton, C. R., Bojang, K., Krause, G., Kremsner, P. G.
Int J Infect Dis, (2023). 134:240-247