Akech S

A Pragmatic Trial of Glucocorticoids for Community-Acquired Pneumonia.Lucinde RK Gathuri H Mwaniki P Orindi B Otieno EO Mwakio S Mulemi L Isaaka L Shangala J Saisi M Isinde E Oginga IN Wachira AW Manuthu E Kariuki H Asaava P Nyikuli J Wekesa C Otedo A Bosire H Okoth SB Ongalo W Mukabi DM Lusamba W Muthui B Adembesa I Mithi C Sood M Aliyan NA Gituma B Matiko MG Omondi CA Ombajo LA Kirui N Ochola L Abdi AI Kagucia EW English M Hamaluba M Ochola-Oyier I Kamuya D Bejon P Barasa E Agweyu A Akech S Etyang AO
N Engl J Med, (2025). 393:2187-2197

A pragmatic randomized controlled trial of standard care versus corticosteroids plus standard care for treatment of pneumonia in adults admitted to Kenyan hospitals (SONIA).Lucinde R Abdi A Orindi B Mwakio S Gathuri H Onyango E Chira S Ogero M Isaaka L Shangala J Oginga IN Wachira A Manuthu E Kariuki H Nyikuli J Wekesa C Otedo A Bosire H Okoth SB Ongalo W Mukabi D Lusamba W Muthui B Kirui N Adembesa I Mithi C Sood M Ahmed N Gituma B Ongaki VB Giabe M Omondi C Ombajo LA Kagucia W English M Hamaluba M Ochola-Oyier LI Kamuya D Bejon P Agweyu A Akech S Etyang AO
Wellcome Open Res, (2025). 7:269

Paediatric anaemia in rural Kenya and the role of travel time to emergency care services.Musau MM Khazenzi C Akech S Omondi E Okiro EA Snow RW Macharia PM Kamau A
Front Epidemiol, (2025). 5:1578522

Implementation of Smart Triage combined with a quality improvement program for children presenting to facilities in Kenya and Uganda: An interrupted time series analysis.Ansermino JM Pillay Y Tagoola A Zhang C Dunsmuir D Kamau S Kigo J Agaba C Aye IA Hwang B Novakowski SK Huxford C Wiens MO Kimutai D Ouma M Ahmed I Mwaniki P Oyella F Tenywa E Nambuya H Toliva BO Kenya-Mugisha N Kissoon N Akech S Pediatric Sepsis CoLab
PLOS Digit Health, (2025). 4:e0000466

Examining the impact of implementing routine rotavirus vaccination on the number of paediatric admissions due to diarrhoea and dehydration in Kenyan hospitals: A study using interrupted time series analysis.Chelangat D Malla L Langat RC Akech S Clinical Information Network Author Group
Wellcome Open Res, (2025). 7:2

Repeatability of RRate measurements in children during triage in two Ugandan hospitals.Asdo A Mawji A Omara I Aye Ishebukara IA Komugisha C Novakowski SK Pillay Y Wiens MO Akech S Oyella F Tagoola A Kissoon N Ansermino JM Dunsmuir D
PLOS Glob Public Health, (2025). 5:e0003097

Effects of health system limitations on the use of blood culture and sensitivity testing in Kenyan county hospitals: an interview-based qualitative study using causal loop diagrams.Bahati F Mutua E Akech S English M Nyamwaya B Gachoki J McKnight J
Lancet Microbe, (2025). 6:100945

Prospective clinical surveillance for severe acute respiratory illness and COVID-19 vaccine effectiveness in Kenyan hospitals during the COVID-19 pandemic.Lucinde RK Gathuri H Isaaka L Ogero M Mumelo L Kimego D Mbevi G Wanyama C Otieno EO Mwakio S Saisi M Isinde E Oginga IN Wachira A Manuthu E Kariuki H Nyikuli J Wekesa C Otedo A Bosire H Okoth SB Ongalo W Mukabi D Lusamba W Muthui B Adembesa I Mithi C Sood M Ahmed N Gituma B Giabe M Omondi C Aman R Amoth P Kasera K Were F Nganga W Berkley JA Tsofa B Mwangangi J Bejon P Barasa E English M Scott JAG Akech S Kagucia EW Agweyu A Etyang AO
BMC Infect Dis, (2024). 24:1246

Evaluation of hydroxychloroquine or chloroquine for the prevention of COVID-19 (COPCOV): A double-blind, randomised, placebo-controlled trial.Schilling WHK Mukaka M Callery JJ Llewelyn MJ Cruz CV Dhorda M Ngernseng T Waithira N Ekkapongpisit M Watson JA Chandna A Nelwan EJ Hamers RL Etyang A Beg MA Sow S Yavo W Allabi AC Basnyat B Sharma SK Amofa-Sekyi M Yonga P Adler A Yuentrakul P Cope T Thaipadungpanit J Rienpradub P Imwong M Abdad MY Blacksell SD Tarning J Goudjo FF Dossou AD Konate-Toure A Assi SB Ouffoue K Nasronudin N Rachman BE Romadhon PZ Dewanto DD Heryana MO Novi T Pasaribu AP Mutiara M Nasution MPR Khairunnisa K Dalimunthe FA Airlangga E Fahrezzy A Subronto Y Ananda NR Rahardjani M Rimainar A Lucinde RK Timbwa M Onyango OE Agutu C Akech S Hamaluba M Kipyego J Ngachi O Haidara FC Traore OY Diarra F Khanal B Dahal P Shrestha S Rijal S Kabore Y Adehossi E Guindo O Qamar FN Kazi AM Woodrow CJ Laird S Cheeba M Ayles H Cheah PY Taylor WRJ Batty EM Chotivanich K Pukrittayakamee S Phumratanaprapin W von Seidlein L Dondorp A Day NPJ White NJ Copcov Collaborative Group
PLoS Med, (2024). 21:e1004428

Comparison between the Smart Triage model and the Emergency Triage Assessment and Treatment guidelines in triaging children presenting to the emergency departments of two public hospitals in Kenya.Kamau S Kigo J Mwaniki P Dunsmuir D Pillay Y Zhang C Nyamwaya B Kimutai D Ouma M Mohammed I Gachuhi K Chege M Thuranira L Ansermino JM Akech S
PLOS Digit Health, (2024). 3:e0000408

Geographical validation of the Smart Triage Model by age group.Zhang C Wiens MO Dunsmuir D Pillay Y Huxford C Kimutai D Tenywa E Ouma M Kigo J Kamau S Chege M Kenya-Mugisha N Mwaka S Dumont GA Kissoon N Akech S Ansermino JM Pediatric Sepsis CoLab
PLOS Digit Health, (2024). 3:e0000311

External validation of a paediatric Smart triage model for use in resource limited facilities.Kigo J Kamau S Mawji A Mwaniki P Dunsmuir D Pillay Y Zhang C Pallot K Ogero M Kimutai D Ouma M Mohamed I Chege M Thuranira L Kissoon N Ansermino JM Akech S
PLOS Digit Health, (2024). 3:e0000293

Severe outcomes of malaria in children under time-varying exposure.De Salazar PM Kamau A Cavelan A Akech S Mpimbaza A Snow RW Penny MA
Nat Commun, (2024). 15:4069

Feasibility, safety, and impact of the RTS,S/AS01(E) malaria vaccine when implemented through national immunisation programmes: evaluation of cluster-randomised introduction of the vaccine in Ghana, Kenya, and Malawi.Asante KP Mathanga DP Milligan P Akech S Oduro A Mwapasa V Moore KA Kwambai TK Hamel MJ Gyan T Westercamp N Kapito-Tembo A Njuguna P Ansong D Kariuki S Mvalo T Snell P Schellenberg D Welega P Otieno L Chimala A Afari EA Bejon P Maleta K Agbenyega T Snow RW Zulu M Chinkhumba J Samuels AM Malaria Vaccine Programme Evaluation Partners
Lancet, (2024). 403:1660-1670

Development and Validation of the Phoenix Criteria for Pediatric Sepsis and Septic Shock.Sanchez-Pinto LN Bennett TD DeWitt PE Russell S Rebull MN Martin B Akech S Albers DJ Alpern ER Balamuth F Bembea M Chisti MJ Evans I Horvat CM Jaramillo-Bustamante JC Kissoon N Menon K Scott HF Weiss SL Wiens MO Zimmerman JJ Argent AC Sorce LR Schlapbach LJ Watson RS Society of Critical Care Medicine Pediatric Sepsis Definition Task Force Biban P Carrol E Chiotos K Flauzino De Oliveira C Hall MW Inwald D Ishimine P Levin M Lodha R Nadel S Nakagawa S Peters MJ Randolph AG Ranjit S Souza DC Tissieres P Wynn JL
JAMA, (2024). 331:675-686

International Consensus Criteria for Pediatric Sepsis and Septic Shock.Schlapbach LJ Watson RS Sorce LR Argent AC Menon K Hall MW Akech S Albers DJ Alpern ER Balamuth F Bembea M Biban P Carrol ED Chiotos K Chisti MJ DeWitt PE Evans I Flauzino de Oliveira C Horvat CM Inwald D Ishimine P Jaramillo-Bustamante JC Levin M Lodha R Martin B Nadel S Nakagawa S Peters MJ Randolph AG Ranjit S Rebull MN Russell S Scott HF de Souza DC Tissieres P Weiss SL Wiens MO Wynn JL Kissoon N Zimmerman JJ Sanchez-Pinto LN Bennett TD Society of Critical Care Medicine Pediatric Sepsis Definition Task Force
JAMA, (2024). 331:665-674

Verbal Autopsy to Assess Postdischarge Mortality in Children With Suspected Sepsis in Uganda.Knappett M Hooft A Maqsood MB Lavoie PM Kortz T Mehta S Duby J Akech S Maina M Carter R Popescu CR Daftary R Mugisha NK Mwesigwa D Kabakyenga J Kumbakumba E Ansermino JM Kissoon N Mutekanga A Hau D Moschovis P Kangwa M Chen C Firnberg M Glomb N Argent A Reid SJ Bhutta A Wiens MO
Pediatrics, (2023). 152:

Pediatric prognostic models predicting inhospital child mortality in resource-limited settings: An external validation study.Ogero M Ndiritu J Sarguta R Tuti T Akech S
Health Sci Rep, (2023). 6:e1433

Recalibrating prognostic models to improve predictions of in-hospital child mortality in resource-limited settings.Ogero M Ndiritu J Sarguta R Tuti T Aluvaala J Akech S
Paediatr Perinat Epidemiol, (2023). 37:313-321

Tackling post-discharge mortality in children living in LMICs to reduce child deaths.Akech S Kwambai T Wiens MO Chandna A Berkley JA Snow RW
Lancet Child Adolesc Health, (2023). 7:149-151