Publications

Epidemiology and Demography

"We should be at the table together from the beginning": perspectives on partnership from stakeholders at four research institutions in sub-Saharan Africa.Voller S Chitalu CM Nyondo-Mipando AL Opobo T Bangirana CA Thorogood N Schellenberg J Chi P
Int J Equity Health, (2022). 21:111

Differences in epidemiology of enteropathogens in children pre- and post-rotavirus vaccine introduction in Kilifi, coastal Kenya.Agoti CN Curran MD Murunga N Ngari M Muthumbi E Lambisia AW Frost SDW Blacklaws BA Nokes DJ Drumright LN
Gut Pathog, (2022). 14:32

Epidemiological impact and cost-effectiveness analysis of COVID-19 vaccination in Kenya.Orangi S Ojal J Brand SP Orlendo C Kairu A Aziza R Ogero M Agweyu A Warimwe GM Uyoga S Otieno E Ochola-Oyier LI Agoti CN Kasera K Amoth P Mwangangi M Aman R Ng'ang'a W Adetifa IM Scott JAG Bejon P Keeling MJ Flasche S Nokes DJ Barasa E
BMJ Glob Health, (2022). 7:

BIRC6 modifies risk of invasive bacterial infection in Kenyan children.Gilchrist JJ Kariuki SN Watson JA Band G Uyoga S Ndila CM Mturi N Mwarumba S Mohammed S Mosobo M Alasoo K Rockett KA Mentzer AJ Kwiatkowski DP Hill AVS Maitland K Scott JAG Williams TN
Elife, (2022). 11:

Improving the diagnosis of severe malaria in African children using platelet counts and plasma PfHRP2 concentrations.Watson JA Uyoga S Wanjiku P Makale J Nyutu GM Mturi N George EC Woodrow CJ Day NPJ Bejon P Opoka RO Dondorp AM John CC Maitland K Williams TN White NJ
Sci Transl Med, (2022). 14:eabn5040

Phagocytosis of Plasmodium falciparum ring-stage parasites predicts protection against malaria.Musasia FK Nkumama IN Frank R Kipkemboi V Schneider M Mwai K Odera DO Rosenkranz M F├╝rle K Kimani D Tuju J Njuguna P Hamaluba M Kapulu MC Wardemann H Abdi AI Abebe Y Bejon P Billingsley PF Bull PC de Laurent Z Hoffman SL James ER Kariuki S Kimathi R Kinyanjui S Kivisi C Makale J Marsh K Mohammed KS Mosobo M Musembi J Musyoki J Muthui M Mwacharo J Ndungu F Ngoi JM Ngoto O Ogutu B Olewe F Omuoyo D OngÔÇÖecha J Otieno E Shangala J Sim BKL Richie TL Wambua J Williams TN Osier Faith HA
Nature Communications, (2022). 13:4098

Sickle cell anaemia and severe Plasmodium falciparum malaria: a secondary analysis of the Transfusion and Treatment of African Children Trial (TRACT).Uyoga S Olupot-Olupot P Connon R Kiguli S Opoka RO Alaroker F Muhindo R Macharia AW Dondorp AM Gibb DM Walker AS George EC Maitland K Williams TN
Lancet Child Adolesc Health, (2022). 6:606-613

Genomic Epidemiology of SARS-CoV-2 in Seychelles, 2020-2021.Morobe JM Pool B Marie L Didon D Lambisia AW Makori T Mohammed KS de Laurent ZR Ndwiga L Mburu MW Moraa E Murunga N Musyoki J Mwacharo J Nyamako L Riako D Ephnatus P Gambo F Naimani J Namulondo J Tembo SZ Ogendi E Balde T Dratibi FA Yahaya AA Gumede N Achilla RA Borus PK Wanjohi DW Tessema SK Mwangangi J Bejon P Nokes DJ Ochola-Oyier LI Githinji G Biscornet L Agoti CN
Viruses, (2022). 14:

Transmission networks of SARS-CoV-2 in Coastal Kenya during the first two waves: A retrospective genomic study.Agoti CN Ochola-Oyier LI Dellicour S Mohammed KS Lambisia AW de Laurent ZR Morobe JM Mburu MW Omuoyo DO Ongera EM Ndwiga L Maitha E Kitole B Suleiman T Mwakinangu M Nyambu JK Otieno J Salim B Musyoki J Murunga N Otieno E Kiiru JN Kasera K Amoth P Mwangangi M Aman R Kinyanjui S Warimwe G Phan M Agweyu A Cotten M Barasa E Tsofa B Nokes DJ Bejon P Githinji G
Elife, (2022). 11:

The impact of malaria-protective red blood cell polymorphisms on parasite biomass in children with severe Plasmodium falciparum malaria.Uyoga S Watson JA Wanjiku P Rop JC Makale J Macharia AW Kariuki SN Nyutu GM Shebe M Mosobo M Mturi N Rockett KA Woodrow CJ Dondorp AM Maitland K White NJ Williams TN
Nat Commun, (2022). 13:3307

The erythrocyte membrane properties of beta thalassaemia heterozygotes and their consequences for Plasmodium falciparum invasion.Introini V Marin-Menendez A Nettesheim G Lin YC Kariuki SN Smith AL Jean L Brewin JN Rees DC Cicuta P Rayner JC Penman BS
Sci Rep, (2022). 12:8934

Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in children younger than 5 years in 2019: a systematic analysis.Li Y Wang X Blau DM Caballero MT Feikin DR Gill CJ Madhi SA Omer SB Simoes EAF Campbell H Pariente AB Bardach D Bassat Q Casalegno JS Chakhunashvili G Crawford N Danilenko D Do LAH Echavarria M Gentile A Gordon A Heikkinen T Huang QS Jullien S Krishnan A Lopez EL Markic J Mira-Iglesias A Moore HC Moyes J Mwananyanda L Nokes DJ Noordeen F Obodai E Palani N Romero C Salimi V Satav A Seo E Shchomak Z Singleton R Stolyarov K Stoszek SK von Gottberg A Wurzel D Yoshida LM Yung CF Zar HJ Respiratory Virus Global Epidemiology Network Nair H Resceu investigators
Lancet, (2022). 399:2047-2064

Incidence of chikungunya virus infections among Kenyan children with neurological disease, 2014-2018: A cohort study.Nyamwaya DK Otiende M Mwango L Kariuki SM Otieno B Omuoyo DO Githinji G Kitsao BS Karanja HK Gitonga JN de Laurent ZR Davies A Mwarumba S Agoti CN Thumbi SM Hamaluba MM Newton CR Bejon P Warimwe GM
PLoS Med, (2022). 19:e1003994

Epidemiology of COVID-19 infections on routine polymerase chain reaction (PCR) and serology testing in Coastal Kenya.Nyagwange J Ndwiga L Muteru K Wamae K Tuju J Testing Team C Kutima B Gitonga J Karanja H Mugo D Kasera K Amoth P Murunga N Babu L Otieno E Githinji G Nokes DJ Tsofa B Orindi B Barasa E Warimwe G Agoti CN Bejon P Ochola-Oyier LI
Wellcome Open Res, (2022). 7:69

Automating Pitted Red Blood Cell Counts Using Deep Neural Network Analysis: A New Method for Measuring Splenic Function in Sickle Cell Anaemia.Nardo-Marino A Braunstein TH Petersen J Brewin JN Mottelson MN Williams TN Kurtzhals JAL Rees DC Glenthoj A
Front Physiol, (2022). 13:859906

A Clinical and Physiological Prospective Observational Study on the Management of Pediatric Shock in the Post-Fluid Expansion as Supportive Therapy Trial Era.Obonyo NG Olupot-Olupot P Mpoya A Nteziyaremye J Chebet M Uyoga S Muhindo R Fanning JP Shiino K Chan J Fraser JF Maitland K
Pediatr Crit Care Med, (2022). 23:502-513

Vitamin D Deficiency and Its Association with Iron Deficiency in African Children.Mogire RM Muriuki JM Morovat A Mentzer AJ Webb EL Kimita W Ndungu FM Macharia AW Cutland CL Sirima SB Diarra A Tiono AB Lule SA Madhi SA Prentice AM Bejon P Pettifor JM Elliott AM Adeyemo A Williams TN Atkinson SH
Nutrients, (2022). 14:

Efficiency of transplacental transfer of respiratory syncytial virus (RSV) specific antibodies among pregnant women in Kenya.Nyiro JU Bukusi E Mwaengo D Nyaguara A Nyawanda B Otieno N Bigogo G Murunga N Widdowson MA Verani JR Chaves SS Mwangudza H Odundo C Berkley JA Nokes DJ Munywoki PK
Wellcome Open Res, (2022). 7:43

TRUE-1: Trial of Repurposed Unithiol for snakebite Envenoming phase 1 (safety, tolerability, pharmacokinetics and pharmacodynamics in healthy Kenyan adults).Abouyannis M FitzGerald R Ngama M Mwangudzah H Nyambura YK Ngome S Riako D Babu L Lewa F Else L Dily Penchala S Orindi B Mumba N Kalama B Ndungu FM Adetifa I Khoo S Lalloo DG Casewell NR Hamaluba M
Wellcome Open Res, (2022). 7:90

Scaling up the primary health integrated care project for chronic conditions in Kenya: study protocol for an implementation research project.Nolte E Kamano JH Naanyu V Etyang A Gasparrini A Hanson K Koros H Mugo R Murphy A Oyando R Pliakas T Were V Willis R Barasa E Perel P
BMJ Open, (2022). 12:e056261