Title :

The essential role of DSMBs in ensuring the ethics of global vaccine trials to address COVID-19

Abstract :

COVID-19 vaccines are being developed and implemented with unprecedented speed. Accordingly, trials considered ethical at their inception may quickly become concerning. We provide recommendations for Data and Safety Monitoring Boards (DSMBs) on monitoring the ethical acceptability of COVID-19 vaccine trials, focusing on placebo-controlled trials in low- and middle-income countries.

Authors :

Eckstein L, Rid A, Kamuya D, Shah SK.

PubMed link :

Journals :

Clin Infect Dis. 2021