Wellcome Open Res


114 results

Examining the development and utilisation of Community-Based Health Information Systems (CBHIS) in Africa: A Scoping Review.Kuvuna B, Nyanchoka M, Guleid F, Ogutu M, Tsofa B, Nzinga J
Wellcome Open Res, (2024). 9:485

A mixed methods study examining the impact of primary health care financing transitions on facility functioning and service delivery in Kenya: a study protocol.Muthuri RNDK, Nzinga J, Tsofa B, Musiega A, Mugo P, Wong E, Mazzilli C, Ng'ang'a W, Hagedorn B, Turner G, Musuva A, Ravishankar N, Murira FM, Barasa E
Wellcome Open Res, (2024). 9:220

A Phase I trial of Non-invasive Ventilation and seizure prophylaxis with levetiracetam In Children with Cerebral Malaria Trial (NOVICE-M Trial).Maitland K, Obonyo N, Hamaluba M, Ogoda E, Mogaka C, Williams TN, Newton C, Kariuki SM, Gibb DM, Walker AS, Connon R, George EC
Wellcome Open Res, (2024). 9:281

SEVUparin as a potential Adjunctive Treatment in children with severe malaria: A phase I trial safety and dose finding trial (SEVUSMAART).Maitland K, Hamaluba M, Obonyo N, Oguda E, Mogoka C, Williams TN, Chaponda M, Miti S, Kamavu LK, Jonathan Gwasupika J, Connon R, Gibb DM, Dondorp A, Day N, White N, Walker AS, George EC
Wellcome Open Res, (2023). 8:484

Utility of MALDI-TOF MS for determination of species identity and blood meal sources of primary malaria vectors on the Kenyan coast.Karisa J, Ominde K, Tuwei M, Bartilol B, Ondieki Z, Musani H, Wanjiku C, Mwikali K, Babu L, Rono M, Eminov M, Mbogo C, Bejon P, Mwangangi J, Laroche M, Maia M
Wellcome Open Res, (2023). 8:151

Safety and immunogenicity of varied doses of R21/Matrix-Mâ„¢ vaccine at three years follow-up: A phase 1b age de-escalation, dose-escalation trial in adults, children, and infants in Kilifi-Kenya.Sang S, Datoo MS, Otieno E, Muiruri C, Bellamy D, Gathuri E, Ngoto O, Musembi J, Provstgaard-Morys S, Stockdale L, Aboagye J, Woods D, Lawrie A, Roberts R, Keter K, Kimani D, Ndungu F, Kapulu M, Njau I, Orindi B, Ewer KJ, Hill AVS, Bejon P, Hamaluba M
Wellcome Open Res, (2023). 8:450

Safety and immunogenicity of ChAdOx1 nCoV-19 (AZD1222) vaccine in adults in Kenya: a phase 1/2 single-blind, randomised controlled trial.Hamaluba M, Sang S, Orindi B, Njau I, Karanja H, Kamau N, Gitonga JN, Mugo D, Wright D, Nyagwange J, Kutima B, Omuoyo D, Mwatasa M, Ngetsa C, Agoti C, Cheruiyot S, Nyaguara A, Munene M, Mturi N, Oloo E, Ochola-Oyier L, Mumba N, Mauncho C, Namayi R, Davies A, Tsofa B, Nduati EW, Aliyan N, Kasera K, Etyang A, Boyd A, Hill A, Gilbert S, Douglas A, Pollard A, Bejon P, Lambe T, Warimwe G
Wellcome Open Res, (2023). 8:182

Mortality among non-severely under nourished children with pneumonia globally: protocol for a systematic review and meta-analysis.Nalwanga D, Bakker C, Kiggwe A, Negash AA, Ocan M, Briend A, Maitland K, Musiiime V, Karamagi C
Wellcome Open Res, (2023). 8:551

Ethical issues of involving people with intellectual disabilities in genomic research: a scoping review protocol.Chepkirui D, Kipkemoi P, Bitta M, Harris E, Musesengwa R, Kamuya D
Wellcome Open Res, (2023). 8:340

Universal iron supplementation: the best strategy to tackle childhood anaemia in malaria-endemic countries?.Karthikappallil R, Atkinson SH
Wellcome Open Res, (2023). 8:345

A rapid review of community engagement and informed consent processes for adaptive platform trials and alternative design trials for public health emergencies.Davies A, Ormel I, Bernier A, Harriss E, Mumba N, Gobat N, Schwartz L, Cheah PY
Wellcome Open Res, (2023). 8:194

Severe anaemia, iron deficiency, and susceptibility to invasive bacterial infections.Abuga KM, Nairz M, MacLennan CA, Atkinson SH
Wellcome Open Res, (2023). 8:48

Assessment of gestational age at antenatal care visits among Kenyan women to inform delivery of a maternal respiratory syncytial virus (RSV) vaccine in low- and middle-income countries.Nyiro JU, Nyawanda BO, Bukusi E, Mureithi MW, Murunga N, Nokes DJ, Bigogo G, Otieno NA, Opere VA, Ouma A, Pecenka C, Munywoki PK
Wellcome Open Res, (2023). 8:154

Using self-supervised feature learning to improve the use of pulse oximeter signals to predict paediatric hospitalization.Mwaniki P, Kamanu T, Akech S, Dunsmuir D, Ansermino JM, Eijkemans MJC
Wellcome Open Res, (2023). 6:248

Pf7: an open dataset of Plasmodium falciparum genome variation in 20,000 worldwide samples.Abdel Hamid MM, Abdelraheem MH, Acheampong DO, Ahouidi A, Ali M, Almagro-Garcia J, Amambua-Ngwa A, Amaratunga C, Amenga-Etego L, Andagalu B, Anderson T, Andrianaranjaka V, Aniebo I, Aninagyei E, Ansah F, Ansah PO, Apinjoh T, Arnaldo P, Ashley E, Auburn S, Awandare GA, Ba H, Baraka V, Barry A, Bejon P, Bertin GI, Boni MF, Borrmann S, Bousema T, Bouyou-Akotet M, Branch O, Bull PC, Cheah H, Chindavongsa K, Chookajorn T, Chotivanich K, Claessens A, Conway DJ, Corredor V, Courtier E, Craig A, D'Alessandro U, Dama S, Day N, Denis B, Dhorda M, Diakite M, Djimde A, Dolecek C, Dondorp A, Doumbia S, Drakeley C, Drury E, Duffy P, Echeverry DF, Egwang TG, Enosse SMM, Erko B, Fairhurst RM, Faiz A, Fanello CA, Fleharty M, Forbes M, Fukuda M, Gamboa D, Ghansah A, Golassa L, Goncalves S, Harrison GLA, Healy SA, Hendry JA, Hernandez-Koutoucheva A, Hien TT, Hill CA, Hombhanje F, Hott A, Htut Y, Hussein M, Imwong M, Ishengoma D, Jackson SA, Jacob CG, Jeans J, Johnson KJ, Kamaliddin C, Kamau E, Keatley J, Kochakarn T, Konate DS, Konaté A, Kone A, Kwiatkowski DP, Kyaw MP, Kyle D, Lawniczak M, Lee SK, Lemnge M, Lim P, Lon C, Loua KM, Mandara CI, Marfurt J, Marsh K, Maude RJ, Mayxay M, Maïga-Ascofaré O, Miotto O, Mita T, Mobegi V, Mohamed AO, Mokuolu OA, Montgomery J, Morang'a CM, Mueller I, Murie K, Newton PN, Ngo Duc T, Nguyen T, Nguyen TN, Nguyen Thi Kim T, Nguyen Van H, Noedl H, Nosten F, Noviyanti R, Ntui VN, Nzila A, Ochola-Oyier LI, Ocholla H, Oduro A, Omedo I, Onyamboko MA, Ouedraogo JB, Oyebola K, Oyibo WA, Pearson R, Peshu N, Phyo AP, Plowe CV, Price RN, Pukrittayakamee S, Quang HH, Randrianarivelojosia M, Rayner JC, Ringwald P, Rosanas-Urgell A, Rovira-Vallbona E, Ruano-Rubio V, Ruiz L, Saunders D, Shayo A, Siba P, Simpson VJ, Sissoko MS, Smith C, Su XZ, Sutherland C, Takala-Harrison S, Talman A, Tavul L, Thanh NV, Thathy V, Thu AM, Toure M, Tshefu A, Verra F, Vinetz J, Wellems TE, Wendler J, White NJ, Whitton G, Yavo W, van der Pluijm RW
Wellcome Open Res, (2023). 8:22

The CINAMR (Clinical Information Network-Antimicrobial Resistance) Project: A pilot microbial surveillance using hospitals linked to regional laboratories in Kenya: Study Protocol.Akech S, Nyamwaya B, Gachoki J, Ogero M, Kigo J, Maina M, Mutua E, Ooko E, Bejon P, Mwarumba S, Bahati F, Mvera B, Musyimi R, Onsare R, Hutter J, Tanui E, Wesangula E, Turner P, Dunachie S, Lucey O, McKnight J
Wellcome Open Res, (2022). 7:256

A network of empirical ethics teams embedded in research programmes across multiple sites: opportunities and challenges in contributing to COVID-19 research and responses.Ngwenya N, Ilo Van Nuil J, Nyirenda D, Chambers M, Cheah PY, Seeley J, Chi P, Mafuleka L, Nkosi B, Kamuya D, Davies A, Schneiders ML, Mumba N, Dlamini S, Desmond N, Marsh V, Rippon D, Parker M, Molyneux S
Wellcome Open Res, (2022). 7:48

Targeted amplicon deep sequencing of ama1 and mdr1 to track within-host P. falciparum diversity throughout treatment in a clinical drug trial.Wamae K, Ndwiga L, Kharabora O, Kimenyi K, Osoti V, de Laurent Z, Wambua J, Musyoki J, Ngetsa C, Kalume P, Mwambingu G, Hamaluba M, van der Pluijm R, Dondorp AM, Bailey J, Juliano J, Bejon P, Ochola-Oyier L
Wellcome Open Res, (2022). 7:95

Strategies for improving mental health and wellbeing used by adults ageing with HIV from the Kenyan coast: a qualitative exploration.Mwangala PN, Wagner RG, Newton CR, Abubakar A
Wellcome Open Res, (2022). 7:221

Addressing the need for an appropriate skilled delivery care workforce in Burundi to support Maternal and Newborn Health Service Delivery Redesign (MNH-Redesign): a sequential study protocol.Habonimana D, Leckcivilize A, Nicodemo C, English M
Wellcome Open Res, (2022). 7:196